检索结果 - Lee Honigberg
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Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer’s disease 由 Kenta Yoshida, Anita Moein, Tobias Bittner, Susanne Ostrowitzki, Helen Lin, Lee Honigberg, Jin Y. Jin, Angelica Quartino
出版 2020Artigo -
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The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy 由 Lee Honigberg, Ashley M. Smith, Mint Sirisawad, Erik Verner, David Loury, Betty Chang, Shyr Li, Zhengying Pan, Douglas H. Thamm, Richard A. Miller, Joseph J. Buggy
出版 2010Artigo -
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Proteomics approach identifies aqueous humor biomarkers in retinal diseases 由 Kevin Huang, CJ Schofield, Trung Nguy, Randall C. Dere, Vincent Wolowski, Juliane Siebourg‐Polster, Andreas Dieckmann, Justus G. Garweg, Michael Chang, Lee Honigberg, Jason A. Hackney, Vahan B. Indjeian
出版 2025Artigo -
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Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q 由 Svetlana Pidasheva, Sara Trifari, Anne Phillips, Jason A. Hackney, Yan Ma, Ashley Smith, Sue J. Sohn, Hergen Spits, Randall D. Little, Timothy W. Behrens, Lee Honigberg, Nico Ghilardi, Hilary Clark
出版 2011Artigo -
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Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF 由 Daniel S. Spellman, Kristin R. Wildsmith, Lee Honigberg, Marianne Tuefferd, David Baker, Nandini Raghavan, Angus C. Nairn, Pascal Croteau, Michael Schirm, René Allard, Julie Lamontagne, Daniel Chelsky, Steven C. Hoffmann, William Z. Potter
出版 2015Artigo -
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Efficacy and Safety of Lampalizumab for Geographic Atrophy Due to Age-Related Macular Degeneration 由 Frank G. Holz, Srinivas R. Sadda, Brandon Busbee, Emily Y. Chew, Paul Mitchell, Adnan Tufail, Christopher Brittain, Daniela Ferrara, Sarah Gray, Lee Honigberg, Jillian Martin, Barbara Tong, Jason S. Ehrlich, Neil M. Bressler
出版 2018Artigo -
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Deep Learning to Predict Geographic Atrophy Area and Growth Rate from Multimodal Imaging 由 Neha Anegondi, Simon S. Gao, Verena Steffen, Richard F. Spaide, Srinivas R. Sadda, Frank G. Holz, Christina Rabe, Lee Honigberg, Elizabeth M. Newton, Julia Cluceru, Michael Kawczynski, Thomas Bengtsson, Daniela Ferrara, Qi Yang
出版 2022Artigo -
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Macular Sensitivity Endpoints in Geographic Atrophy: Exploratory Analysis of Chroma and Spectri Clinical Trials 由 Dolly S. Chang, Natalia F. Callaway, Verena Steffen, Karl G. Csaky, Robyn H. Guymer, David G. Birch, Praveen J. Patel, Michael S. Ip, Simon S. Gao, Jayla Briggs, Lee Honigberg, Phillip Lai, Daniela Ferrara, Yasir J. Sepah
出版 2023Artigo -
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Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration 由 Brian L. Yaspan, David F. Williams, Frank G. Holz, Carl D. Regillo, Zhengrong Li, Amy Dressen, Menno van Lookeren Campagne, Kha Le, Robert Graham, Tatiana Beres, Tushar Bhangale, Lee Honigberg, Ashley Smith, Erin C. Henry, Carole Ho, Erich C. Strauss
出版 2017Artigo -
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ABBY 由 Jeffrey L. Cummings, Sharon Cohen, Christopher H. van Dyck, Mark Brody, Craig Curtis, Yong‐Yeon Cho, Michael E. Ward, Michel Friesenhahn, Christina Rabe, Flávia Brunstein, Angelica Quartino, Lee Honigberg, Reina N. Fuji, David Clayton, Deborah L. Mortensen, Carole Ho, Robert Paul
出版 2018Artigo -
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Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mil... 由 Stephen Salloway, Lee Honigberg, Yong‐Yeon Cho, Michael E. Ward, Michel Friesenhahn, Flávia Brunstein, Angelica Quartino, David Clayton, Deborah L. Mortensen, Tobias Bittner, Carole Ho, Christina Rabe, Stephen Schauer, Kristin R. Wildsmith, Reina N. Fuji, Shehnaaz Suliman, Eric M. Reiman, Kewei Chen, Robert Paul
出版 2018Artigo -
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Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy 由 Irene Tom, Victoria C. Pham, Kenneth J. Katschke, Wěi Li, Wei‐Ching Liang, Johnny Gutierrez, Andrew Ah Young, Isabel Figueroa, Shadi Toghi Eshghi, Chingwei V. Lee, Jitendra Kanodia, Scott J. Snipas, Guy S. Salvesen, Phillip Lai, Lee Honigberg, Menno van Lookeren Campagne, Daniel Kirchhofer, Amos Baruch, Jennie R. Lill
出版 2020Artigo -
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The Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical <i>PSEN1</i> E280A mutation carriers to eval... 由 Pierre N. Tariot, Francisco Lopera, Jessica B. Langbaum, Ronald G. Thomas, Suzanne Hendrix, Lon S. Schneider, Silvia Ríos‐Romenets, Margarita Giraldo, Natalia Acosta‐Baena, Carlos Tobón, Cláudia Ramos, Alejandro Palacios Espinosa, Yong‐Yeon Cho, Michael E. Ward, David Clayton, Michael Friesenhahn, Howard Mackey, Lee Honigberg, Sandra Sanabria Bohórquez, Kewei Chen, Trisha Walsh, Carolyn Langlois, Eric M. Reiman
出版 2018Artigo -
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A Phase 1 study of <scp>GDC</scp>‐0134, a dual leucine zipper kinase inhibitor, in <scp>ALS</scp> 由 Jonathan Katz, Jeffrey D. Rothstein, Merit Cudkowicz, Angela Genge, Björn Oskarsson, Avis B. Hains, Chen Chen, Joshua Galanter, Braydon L. Burgess, Yong‐Yeon Cho, Geoffrey A. Kerchner, Felix L. Yeh, Arundhati Sengupta Ghosh, Sravanthi Cheeti, Logan Brooks, Lee Honigberg, Jessica A. Couch, Michael E. Rothenberg, Flávia Brunstein, Khema R. Sharma, Leonard van den Berg, James Berry, Jonathan D. Glass
出版 2022Artigo -
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Systems genomics in age-related macular degeneration 由 Anneke I. den Hollander, Robert F. Mullins, Luz D. Orozco, Andrew P. Voigt, Hsu-Hsin Chen, Tobias Strunz, Felix Graßmann, Jonathan L. Haines, Jonas J. W. Kuiper, Santa J. Tumminia, Rando Allikmets, Gregory S. Hageman, Dwight Stambolian, Caroline C. W. Klaver, Jef D. Boeke, Hao Chen, Lee Honigberg, Suresh Katti, Kelly A. Frazer, Bernhard H. F. Weber, Michael B. Gorin
出版 2022Artigo -
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Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease 由 Susanne Ostrowitzki, Tobias Bittner, Kaycee M. Sink, Howard Mackey, Christina Rabe, Lawrence S. Honig, Emanuele Cassetta, Mark Woodward, Merçé Boada, Christopher H. van Dyck, Timo Grimmer, Dennis J. Selkoe, Andres Schneider, Kathleen Blondeau, Nan Hu, Angelica Quartino, David Clayton, Michael Dolton, Yifan Dang, Beth L. Ostaszewski, Sandra Sanabria Bohórquez, Michael Rabbia, Balázs István Tóth, Udo Eichenlaub, Jillian Smith, Lee Honigberg, Rachelle S. Doody
出版 2022Artigo
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Medicine
Internal medicine
Biology
Disease
Biochemistry
Clinical trial
Immunology
Pathology
Gene
Ophthalmology
Alzheimer's disease
Antibody
Macular degeneration
Pharmacology
Alternative medicine
Genetics
Geographic atrophy
Placebo
Atrophy
Biomarker
Cerebrospinal fluid
Chemistry
Computational biology
Computer science
Dementia
Genotype
Oncology
Psychology
Single-nucleotide polymorphism
Adverse effect