Resultados da busca - Lee Honigberg

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  1. 1
    Alternative Complement Pathway Inhibition by Lampalizumab

    Alternative Complement Pathway Inhibition by Lampalizumab por Rose Edmonds, Verena Steffen, Lee Honigberg, Michael Chang

    Publicado em 2023
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  2. 2
    Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitor

    Inhibition of IgE-mediated secretion from human basophils with a highly selective Bruton's tyrosine kinase, Btk, inhibitor por Donald W. MacGlashan, Lee Honigberg, Ashley Smith, Joseph J. Buggy, John T. Schroeder

    Publicado em 2011
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  3. 3
    Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer’s disease

    Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer’s disease por Kenta Yoshida, Anita Moein, Tobias Bittner, Susanne Ostrowitzki, Helen Lin, Lee Honigberg, Jin Y. Jin, Angelica Quartino

    Publicado em 2020
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  4. 4
    Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics

    Identification of longitudinally dynamic biomarkers in Alzheimer’s disease cerebrospinal fluid by targeted proteomics por Kristin R. Wildsmith, Stephen Schauer, Ashley M. Smith, David Arnott, Yuda Zhu, Joshua Haznedar, Surinder Kaur, W. Rodney Mathews, Lee Honigberg

    Publicado em 2014
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  5. 5
    The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

    The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy por Lee Honigberg, Ashley M. Smith, Mint Sirisawad, Erik Verner, David Loury, Betty Chang, Shyr Li, Zhengying Pan, Douglas H. Thamm, Richard A. Miller, Joseph J. Buggy

    Publicado em 2010
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  6. 6
    Identification of Substrates of Human Protein-tyrosine Phosphatase PTPN22

    Identification of Substrates of Human Protein-tyrosine Phosphatase PTPN22 por Jian Wu, Anjali Katrekar, Lee Honigberg, Ashley M. Smith, Marion Conn, Jie Tang, D. Molkentin Jeffery, Kyle Mortara, Jun Sampang, Steven Williams, Joseph J. Buggy, James M. Clark

    Publicado em 2006
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  7. 7
    Proteomics approach identifies aqueous humor biomarkers in retinal diseases

    Proteomics approach identifies aqueous humor biomarkers in retinal diseases por Kevin Huang, CJ Schofield, Trung Nguy, Randall C. Dere, Vincent Wolowski, Juliane Siebourg‐Polster, Andreas Dieckmann, Justus G. Garweg, Michael Chang, Lee Honigberg, Jason A. Hackney, Vahan B. Indjeian

    Publicado em 2025
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  8. 8
    Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q

    Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q por Svetlana Pidasheva, Sara Trifari, Anne Phillips, Jason A. Hackney, Yan Ma, Ashley Smith, Sue J. Sohn, Hergen Spits, Randall D. Little, Timothy W. Behrens, Lee Honigberg, Nico Ghilardi, Hilary Clark

    Publicado em 2011
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  9. 9
    Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF

    Development and evaluation of a multiplexed mass spectrometry based assay for measuring candidate peptide biomarkers in Alzheimer's Disease Neuroimaging Initiative (ADNI) CSF por Daniel S. Spellman, Kristin R. Wildsmith, Lee Honigberg, Marianne Tuefferd, David Baker, Nandini Raghavan, Angus C. Nairn, Pascal Croteau, Michael Schirm, René Allard, Julie Lamontagne, Daniel Chelsky, Steven C. Hoffmann, William Z. Potter

    Publicado em 2015
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  10. 10
    Efficacy and Safety of Lampalizumab for Geographic Atrophy Due to Age-Related Macular Degeneration

    Efficacy and Safety of Lampalizumab for Geographic Atrophy Due to Age-Related Macular Degeneration por Frank G. Holz, Srinivas R. Sadda, Brandon Busbee, Emily Y. Chew, Paul Mitchell, Adnan Tufail, Christopher Brittain, Daniela Ferrara, Sarah Gray, Lee Honigberg, Jillian Martin, Barbara Tong, Jason S. Ehrlich, Neil M. Bressler

    Publicado em 2018
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  11. 11
    Deep Learning to Predict Geographic Atrophy Area and Growth Rate from Multimodal Imaging

    Deep Learning to Predict Geographic Atrophy Area and Growth Rate from Multimodal Imaging por Neha Anegondi, Simon S. Gao, Verena Steffen, Richard F. Spaide, Srinivas R. Sadda, Frank G. Holz, Christina Rabe, Lee Honigberg, Elizabeth M. Newton, Julia Cluceru, Michael Kawczynski, Thomas Bengtsson, Daniela Ferrara, Qi Yang

    Publicado em 2022
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  12. 12
    Macular Sensitivity Endpoints in Geographic Atrophy: Exploratory Analysis of Chroma and Spectri Clinical Trials

    Macular Sensitivity Endpoints in Geographic Atrophy: Exploratory Analysis of Chroma and Spectri Clinical Trials por Dolly S. Chang, Natalia F. Callaway, Verena Steffen, Karl G. Csaky, Robyn H. Guymer, David G. Birch, Praveen J. Patel, Michael S. Ip, Simon S. Gao, Jayla Briggs, Lee Honigberg, Phillip Lai, Daniela Ferrara, Yasir J. Sepah

    Publicado em 2023
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  13. 13
    Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration

    Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration por Brian L. Yaspan, David F. Williams, Frank G. Holz, Carl D. Regillo, Zhengrong Li, Amy Dressen, Menno van Lookeren Campagne, Kha Le, Robert Graham, Tatiana Beres, Tushar Bhangale, Lee Honigberg, Ashley Smith, Erin C. Henry, Carole Ho, Erich C. Strauss

    Publicado em 2017
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  14. 14
    ABBY

    ABBY por Jeffrey L. Cummings, Sharon Cohen, Christopher H. van Dyck, Mark Brody, Craig Curtis, Yong‐Yeon Cho, Michael E. Ward, Michel Friesenhahn, Christina Rabe, Flávia Brunstein, Angelica Quartino, Lee Honigberg, Reina N. Fuji, David Clayton, Deborah L. Mortensen, Carole Ho, Robert Paul

    Publicado em 2018
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  15. 15
    Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer’s disease (BLAZE)

    Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mil... por Stephen Salloway, Lee Honigberg, Yong‐Yeon Cho, Michael E. Ward, Michel Friesenhahn, Flávia Brunstein, Angelica Quartino, David Clayton, Deborah L. Mortensen, Tobias Bittner, Carole Ho, Christina Rabe, Stephen Schauer, Kristin R. Wildsmith, Reina N. Fuji, Shehnaaz Suliman, Eric M. Reiman, Kewei Chen, Robert Paul

    Publicado em 2018
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  16. 16
    Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy

    Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy por Irene Tom, Victoria C. Pham, Kenneth J. Katschke, Wěi Li, Wei‐Ching Liang, Johnny Gutierrez, Andrew Ah Young, Isabel Figueroa, Shadi Toghi Eshghi, Chingwei V. Lee, Jitendra Kanodia, Scott J. Snipas, Guy S. Salvesen, Phillip Lai, Lee Honigberg, Menno van Lookeren Campagne, Daniel Kirchhofer, Amos Baruch, Jennie R. Lill

    Publicado em 2020
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  17. 17
    The Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical <i>PSEN1</i> E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal‐dominant Alzheimer's disease, including a placebo‐treated noncarrier cohort

    The Alzheimer's Prevention Initiative Autosomal‐Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical <i>PSEN1</i> E280A mutation carriers to eval... por Pierre N. Tariot, Francisco Lopera, Jessica B. Langbaum, Ronald G. Thomas, Suzanne Hendrix, Lon S. Schneider, Silvia Ríos‐Romenets, Margarita Giraldo, Natalia Acosta‐Baena, Carlos Tobón, Cláudia Ramos, Alejandro Palacios Espinosa, Yong‐Yeon Cho, Michael E. Ward, David Clayton, Michael Friesenhahn, Howard Mackey, Lee Honigberg, Sandra Sanabria Bohórquez, Kewei Chen, Trisha Walsh, Carolyn Langlois, Eric M. Reiman

    Publicado em 2018
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  18. 18
    A Phase 1 study of <scp>GDC</scp>‐0134, a dual leucine zipper kinase inhibitor, in <scp>ALS</scp>

    A Phase 1 study of <scp>GDC</scp>‐0134, a dual leucine zipper kinase inhibitor, in <scp>ALS</scp> por Jonathan Katz, Jeffrey D. Rothstein, Merit Cudkowicz, Angela Genge, Björn Oskarsson, Avis B. Hains, Chen Chen, Joshua Galanter, Braydon L. Burgess, Yong‐Yeon Cho, Geoffrey A. Kerchner, Felix L. Yeh, Arundhati Sengupta Ghosh, Sravanthi Cheeti, Logan Brooks, Lee Honigberg, Jessica A. Couch, Michael E. Rothenberg, Flávia Brunstein, Khema R. Sharma, Leonard van den Berg, James Berry, Jonathan D. Glass

    Publicado em 2022
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  19. 19
    Systems genomics in age-related macular degeneration

    Systems genomics in age-related macular degeneration por Anneke I. den Hollander, Robert F. Mullins, Luz D. Orozco, Andrew P. Voigt, Hsu-Hsin Chen, Tobias Strunz, Felix Graßmann, Jonathan L. Haines, Jonas J. W. Kuiper, Santa J. Tumminia, Rando Allikmets, Gregory S. Hageman, Dwight Stambolian, Caroline C. W. Klaver, Jef D. Boeke, Hao Chen, Lee Honigberg, Suresh Katti, Kelly A. Frazer, Bernhard H. F. Weber, Michael B. Gorin

    Publicado em 2022
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  20. 20
    Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease

    Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease por Susanne Ostrowitzki, Tobias Bittner, Kaycee M. Sink, Howard Mackey, Christina Rabe, Lawrence S. Honig, Emanuele Cassetta, Mark Woodward, Merçé Boada, Christopher H. van Dyck, Timo Grimmer, Dennis J. Selkoe, Andres Schneider, Kathleen Blondeau, Nan Hu, Angelica Quartino, David Clayton, Michael Dolton, Yifan Dang, Beth L. Ostaszewski, Sandra Sanabria Bohórquez, Michael Rabbia, Balázs István Tóth, Udo Eichenlaub, Jillian Smith, Lee Honigberg, Rachelle S. Doody

    Publicado em 2022
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