Suchergebnisse - Leboulch, Philippe

Current and future alternative therapies for beta-thalassemia major von de Dreuzy, Edouard, Bhukhai, Kanit, Leboulch, Philippe, Payen, Emmanuel

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Design of a trans protease lentiviral packaging system that produces high titer virus von Westerman, Karen A, Ao, Zhujun, Cohen, Éric A, Leboulch, Philippe

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Is normal hematopoiesis maintained solely by long-term multipotent stem cells? von Cavazzana-Calvo, Marina, Fischer, Alain, Bushman, Frederic D., Payen, Emmanuel, Hacein-Bey-Abina, Salima, Leboulch, Philippe

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High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing von Ling, Chen, Bhukhai, Kanit, Yin, Zifei, Tan, Mengqun, Yoder, Mervin C., Leboulch, Philippe, Payen, Emmanuel, Srivastava, Arun

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Phosphatidylinositol 3-Kinase/Akt Induced by Erythropoietin Renders the Erythroid Differentiation Factor GATA-1 Competent for TIMP-1 Gene Transactivation von Kadri, Zahra, Maouche-Chretien, Leila, Rooke, Heather M., Orkin, Stuart H., Romeo, Paul-Henri, Mayeux, Patrick, Leboulch, Philippe, Chretien, Stany

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Direct Binding of pRb/E2F-2 to GATA-1 Regulates Maturation and Terminal Cell Division during Erythropoiesis von Kadri, Zahra, Shimizu, Ritsuko, Ohneda, Osamu, Maouche-Chretien, Leila, Gisselbrecht, Sylvie, Yamamoto, Masayuki, Romeo, Paul-Henri, Leboulch, Philippe, Chretien, Stany

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Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion von Negre, Olivier, Fusil, Floriane, Colomb, Charlotte, Roth, Shoshannah, Gillet-Legrand, Beatrix, Henri, Annie, Beuzard, Yves, Bushman, Frederic, Leboulch, Philippe, Payen, Emmanuel

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Immortalization of a primate bipotent epithelial liver stem cell von Allain, Jean-Etienne, Dagher, Ibrahim, Mahieu-Caputo, Dominique, Loux, Nathalie, Andreoletti, Marion, Westerman, Karen, Briand, Pascale, Franco, Dominique, Leboulch, Philippe, Weber, Anne

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Heme-regulated eIF2α kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency von Han, An-Ping, Yu, Channing, Lu, Linrong, Fujiwara, Yuko, Browne, Carol, Chin, Gregory, Fleming, Mark, Leboulch, Philippe, Orkin, Stuart H., Chen, Jane-Jane

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Dynamics of gene-modified progenitor cells analyzed by tracking retroviral integration sites in a human SCID-X1 gene therapy trial von Wang, Gary P., Berry, Charles C., Malani, Nirav, Leboulch, Philippe, Fischer, Alain, Hacein-Bey-Abina, Salima, Cavazzana-Calvo, Marina, Bushman, Frederic D.

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Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies von Mouka, Aurélie, Izard, Vincent, Tachdjian, Gérard, Brisset, Sophie, Yates, Frank, Mayeur, Anne, Drévillon, Loïc, Jarray, Rafika, Leboulch, Philippe, Maouche-Chrétien, Leila, Tosca, Lucie

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Preselection of retrovirally transduced bone marrow avoids subsequent stem cell gene silencing and age-dependent extinction of expression of human β-globin in engrafted mice von Kalberer, Christian P., Pawliuk, Robert, Imren, Suzan, Bachelot, Thomas, Takekoshi, Ken J., Fabry, Mary, Eaves, Connie J., London, Irving M., Humphries, R. Keith, Leboulch, Philippe

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Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the β(A(T87Q))-Globin Gene von Negre, Olivier, Eggimann, Anne-Virginie, Beuzard, Yves, Ribeil, Jean-Antoine, Bourget, Philippe, Borwornpinyo, Suparerk, Hongeng, Suradej, Hacein-Bey, Salima, Cavazzana, Marina, Leboulch, Philippe, Payen, Emmanuel

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High-level β-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells von Imren, Suzan, Fabry, Mary E., Westerman, Karen A., Pawliuk, Robert, Tang, Patrick, Rosten, Patricia M., Nagel, Ronald L., Leboulch, Philippe, Eaves, Connie J., Humphries, R. Keith

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Stem Cell Factor-Displaying Simian Immunodeficiency Viral Vectors Together with a Low Conditioning Regimen Allow for Long-Term Engraftment of Gene-Marked Autologous Hematopoietic S... von Verhoeyen, Els, Relouzat, Francis, Cambot, Marie, Costa, Caroline, Nègre, Didier, Legrand, Faézeh, Joubert, Christophe, Grand, Roger Le, Cosset, François-Loïc, Leboulch, Philippe, Dubart-Kupperschmitt, Anne, Prost, Stephane

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UM171 Enhances Lentiviral Gene Transfer and Recovery of Primitive Human Hematopoietic Cells von Ngom, Mor, Imren, Suzan, Maetzig, Tobias, Adair, Jennifer E., Knapp, David J.H.F., Chagraoui, Jalila, Fares, Iman, Bordeleau, Marie-Eve, Sauvageau, Guy, Leboulch, Philippe, Eaves, Connie, Humphries, Richard Keith

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A method to sequence and quantify DNA integration for monitoring outcome in gene therapy von Brady, Troy, Roth, Shoshannah L., Malani, Nirav, Wang, Gary P., Berry, Charles C., Leboulch, Philippe, Hacein-Bey-Abina, Salima, Cavazzana-Calvo, Marina, Papapetrou, Eirini P., Sadelain, Michel, Savilahti, Harri, Bushman, Frederic D.

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Distribution of Lentiviral Vector Integration Sites in Mice Following Therapeutic Gene Transfer to Treat β-thalassemia von Ronen, Keshet, Negre, Olivier, Roth, Shannah, Colomb, Charlotte, Malani, Nirav, Denaro, Maria, Brady, Troy, Fusil, Floriane, Gillet-Legrand, Beatrix, Hehir, Kathleen, Beuzard, Yves, Leboulch, Philippe, Down, Julian D, Payen, Emmanuel, Bushman, Frederic D

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Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia von Nualkaew, Tiwaporn, Sii-Felice, Karine, Giorgi, Marie, McColl, Bradley, Gouzil, Julie, Glaser, Astrid, Voon, Hsiao P.J., Tee, Hsin Y., Grigoriadis, George, Svasti, Saovaros, Fucharoen, Suthat, Hongeng, Suradej, Leboulch, Philippe, Payen, Emmanuel, Vadolas, Jim

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Atypical BSE (BASE) Transmitted from Asymptomatic Aging Cattle to a Primate von Comoy, Emmanuel E., Casalone, Cristina, Lescoutra-Etchegaray, Nathalie, Zanusso, Gianluigi, Freire, Sophie, Marcé, Dominique, Auvré, Frédéric, Ruchoux, Marie-Magdeleine, Ferrari, Sergio, Monaco, Salvatore, Salès, Nicole, Caramelli, Maria, Leboulch, Philippe, Brown, Paul, Lasmézas, Corinne I., Deslys, Jean-Philippe

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