Search Results - Leanne de Koning

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  1. 1
    Heat Shock Protein 90α (Hsp90α) Is Phosphorylated in Response to DNA Damage and Accumulates in Repair Foci

    Heat Shock Protein 90α (Hsp90α) Is Phosphorylated in Response to DNA Damage and Accumulates in Repair Foci by Maria Quanz, Aurélie Herbette, Mano Sayarath, Leanne de Koning, Thierry Dubois, Jian‐Sheng Sun, Marie Dutreix

    Published 2012
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  2. 2
    Heterochromatin protein 1α: a hallmark of cell proliferation relevant to clinical oncology

    Heterochromatin protein 1α: a hallmark of cell proliferation relevant to clinical oncology by Leanne de Koning, Alexia Savignoni, Charlène Boumendil, Haniya Rehman, Bernard Asselain, Xavier Sastre‐Garau, Geneviève Almouzni

    Published 2009
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  3. 3
    NormaCurve: A SuperCurve-Based Method That Simultaneously Quantifies and Normalizes Reverse Phase Protein Array Data

    NormaCurve: A SuperCurve-Based Method That Simultaneously Quantifies and Normalizes Reverse Phase Protein Array Data by Sylvie Troncale, Aurélie Barbet, Lamine Coulibaly, Émilie Henry, Beilei He, Emmanuel Barillot, Thierry Dubois, Philippe Hupé, Leanne de Koning

    Published 2012
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  4. 4
    ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels

    ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels by Sophie Rondeau, Sophie Vacher, Leanne de Koning, Adrien Briaux, Anne Schnitzler, Walid Chemlali, Céline Callens, Rosette Lidereau, Ivan Bièche

    Published 2015
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  5. 5
    Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer

    Asf1b, the necessary Asf1 isoform for proliferation, is predictive of outcome in breast cancer by Armelle Corpet, Leanne de Koning, Joern Toedling, Alexia Savignoni, Frédérique Berger, Charlène Lemaître, Roderick J. O’Sullivan, Jan Karlseder, Emmanuel Barillot, Bernard Asselain, Xavier Sastre‐Garau, Geneviève Almouzni

    Published 2010
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  6. 6
    Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer

    Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer by Didier Meseure, Sophie Vacher, François Lallemand, Kinan Drak Alsibai, Rana Hatem, Walid Chemlali, Nicolás André, Leanne de Koning, Éric Pasmant, Céline Callens, Rosette Lidereau, Antonin Morillon, Ivan Bièche

    Published 2016
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  7. 7
    Co-occurring Mutations of Tumor Suppressor Genes, <i>LATS2</i> and <i>NF2</i>, in Malignant Pleural Mesothelioma

    Co-occurring Mutations of Tumor Suppressor Genes, <i>LATS2</i> and <i>NF2</i>, in Malignant Pleural Mesothelioma by Robin Tranchant, Lisa Quetel, Anne Tallet, Clément Meiller, Annie Renier, Leanne de Koning, Aurélien de Reyniès, Françoise Le Pimpec‐Barthes, Jessica Zucman‐Rossi, Marie‐Claude Jaurand, Didier Jean

    Published 2016
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  8. 8
    Realizing the Promise of Reverse Phase Protein Arrays for Clinical, Translational, and Basic Research: A Workshop Report

    Realizing the Promise of Reverse Phase Protein Arrays for Clinical, Translational, and Basic Research: A Workshop Report by Rehan Akbani, Karl‐Friedrich Becker, Neil O. Carragher, Ted Goldstein, Leanne de Koning, Ulrike Korf, Lance A. Liotta, Gordon B. Mills, Satoshi Nishizuka, Michael Pawlak, Emanuel F. Petricoin, Harvey B. Pollard, Bryan Serrels, Jingchun Zhu

    Published 2014
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  9. 9
    The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma

    The histone chaperone HJURP is a new independent prognostic marker for luminal A breast carcinoma by Rocío Montes de, Zachary A. Gurard‐Levin, Frédérique Berger, Haniya Rehman, Elise Martel, Armelle Corpet, Leanne de Koning, Isabelle Vassias, Laurence O.W. Wilson, Didier Meseure, Fabien Reyal, Alexia Savignoni, Bernard Asselain, Xavier Sastre‐Garau, Geneviève Almouzni

    Published 2014
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  10. 10
    AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin

    AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin by Christophe Couderc, Alizée Boin, Laetitia Fuhrmann, Anne Vincent‐Salomon, Vinay Mandati, Yann Kieffer, Fatima Mechta‐Grigoriou, Laurence Del Maestro, Philippe Chavrier, David Vallerand, Isabelle Brito, Thierry Dubois, Leanne de Koning, Daniel Bouvard, Daniel Louvard, Alexis Gautreau, Dominique Lallemand

    Published 2016
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  11. 11
    Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma

    Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma by Guillaume Carita, Estelle Frisch-Dit-Leitz, Ahmed Dahmani, Chloé Raymondie, Nathalie Cassoux, Sophie Piperno‐Neumann, Fariba Némati, Cécile Laurent, Leanne de Koning, Ensar Halilovic, Sébastien Jeay, Andrew A. Wylie, W. Marston Linehan, Sergio Román-Román, Marie Schoumacher, Didier Decaudin

    Published 2016
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  12. 12
    Proliferation Markers Are Associated with MET Expression in Hepatocellular Carcinoma and Predict Tivantinib Sensitivity <i>In Vitro</i>

    Proliferation Markers Are Associated with MET Expression in Hepatocellular Carcinoma and Predict Tivantinib Sensitivity <i>In Vitro</i> by Sandra Rebouissou, Tiziana La Bella, Samia Rekik, Sandrine Imbeaud, Anna-Line Calatayud, Nataliya Rohr‐Udilova, Yoann Martin, Gabrielle Couchy, Paulette Bioulac‐Sage, Bettina Grasl‐Kraupp, Leanne de Koning, Nathalie Ganne‐Carrié, Jean‐Charles Nault, Marianne Ziol, Jessica Zucman‐Rossi

    Published 2017
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  13. 13
    TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer

    TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer by Virginie Maire, Céline Baldeyron, Marion Richardson, Bruno Tesson, Anne Vincent‐Salomon, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne de Koning, Guillem Rigaill, Aurélie Dumont, David Gentien, Emmanuel Barillot, Sergio Román-Román, Stéphane Depil, Francisco Cruzalegui, Alain Pierré, Gordon C. Tucker, Thierry Dubois

    Published 2013
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  14. 14
    Consensus on precision medicine for metastatic cancers: a report from the MAP conference

    Consensus on precision medicine for metastatic cancers: a report from the MAP conference by Charles Swanton, J.C. Soria, Alberto Bardelli, Andrew V. Biankin, Carlos Caldas, Sarat Chandarlapaty, Leanne de Koning, Caroline Dive, Jean Feunteun, Suet Yi Leung, Richard Marais, Elaine R. Mardis, Nicholas McGranahan, Gary Middleton, Sergio A. Quezada, Jordi Rodón, Nitzan Rosenfeld, C. Sotiriou, Fabrice André

    Published 2016
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  15. 15
    So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020

    So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020 by Manuel Rodrigues, Leanne de Koning, Sarah E. Coupland, Aart G. Jochemsen, Richard Marais, Marc‐Henri Stern, André Lopes Valente, Raymond L. Barnhill, Nathalie Cassoux, Andrew Evans, Iain Galloway, Martine J. Jager, Ellen Kapiteijn, Bożena Romanowska‐Dixon, Bettina Ryll, Sergio Román-Román, Sophie Piperno‐Neumann

    Published 2019
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  16. 16
    Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers

    Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers by Florence Coussy, Rania El Botty, Marion Lavigne, Céline Gu, Laetitia Fuhrmann, Adrien Briaux, Leanne de Koning, A. Dahmani, Élodie Montaudon, Ludivine Morisset, Léa Huguet, Laura Sourd, Pierre Painsec, Sophie Château‐Joubert, Thibaut Larcher, Sophie Vacher, Samia Melaabi, Anne Vincent‐Salomon, Elisabetta Marangoni, Ivan Bièche

    Published 2020
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  17. 17
    Patient‐derived xenografts recapitulate molecular features of human uveal melanomas

    Patient‐derived xenografts recapitulate molecular features of human uveal melanomas by Cécile Laurent, David Gentien, Sophie Piperno‐Neumann, Fariba Némati, Nicolás André, Bruno Tesson, Laurence Desjardins, Pascale Mariani, Audrey Rapinat, Xavier Sastre‐Garau, Jérôme Couturier, Philippe Hupé, Leanne de Koning, Thierry Dubois, Sergio Román-Román, Marc‐Henri Stern, Emmanuel Barillot, J. William Harbour, Simon Saule, Didier Decaudin

    Published 2013
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  18. 18
    Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications

    Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications by Yuna Blum, Clément Meiller, Lisa Quetel, Nabila Elarouci, Mira Ayadi, Danisa Tashtanbaeva, Lucile Armenoult, François Montagne, Robin Tranchant, Annie Renier, Leanne de Koning, Marie‐Christine Copin, Paul Hofman, Véronique Hofman, Henri Porte, Françoise Le Pimpec‐Barthes, Jessica Zucman‐Rossi, Marie‐Claude Jaurand, Aurélien de Reyniès, Didier Jean

    Published 2019
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  19. 19
    Genomic Profiling of Metastatic Uveal Melanoma and Clinical Results of a Phase I Study of the Protein Kinase C Inhibitor AEB071

    Genomic Profiling of Metastatic Uveal Melanoma and Clinical Results of a Phase I Study of the Protein Kinase C Inhibitor AEB071 by Sophie Piperno‐Neumann, James Larkin, Richard D. Carvajal, Jason J. Luke, Gary K. Schwartz, F. Stephen Hodi, Marie‐Paule Sablin, Alexander N. Shoushtari, Sebastian Szpakowski, Niladri Roy Chowdhury, A. Rose Brannon, Thiruvamoor Ramkumar, Leanne de Koning, Adnan Derti, W. Marston Linehan, Padmaja Yerramilli-Rao, Ellen Kapiteijn

    Published 2020
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  20. 20
    Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer

    Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer by Virginie Maire, Fariba Némati, Marion Richardson, Anne Vincent‐Salomon, Bruno Tesson, Guillem Rigaill, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne de Koning, Guillaume Lang, David Gentien, Aurélie Dumont, Emmanuel Barillot, Elisabetta Marangoni, Didier Decaudin, Sergio Román-Román, Alain St. Pierre, Francisco Cruzalegui, Stéphane Depil, Gordon C. Tucker, Thierry Dubois

    Published 2012
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