Search Results - Lawson, Alastair D G

Small Molecule Targeting of Protein–Protein Interactions through Allosteric Modulation of Dynamics by Cossins, Benjamin P., Lawson, Alastair D. G.

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Natural Conformational Sampling of Human TNFα Visualized by Double Electron-Electron Resonance by Carrington, Bruce, Myers, William K., Horanyi, Peter, Calmiano, Mark, Lawson, Alastair D.G.

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Rings in Clinical Trials and Drugs: Present and Future by Shearer, Jonathan, Castro, Jose L., Lawson, Alastair D. G., MacCoss, Malcolm, Taylor, Richard D.

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Modulating Target Protein Biology Through the Re-mapping of Conformational Distributions Using Small Molecules by Lawson, Alastair D. G., MacCoss, Malcolm, Baeten, Dominique L., Macpherson, Alex, Shi, Jiye, Henry, Alistair J.

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Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping by Liu, Xiaofeng, Taylor, Richard D., Griffin, Laura, Coker, Shu-Fen, Adams, Ralph, Ceska, Tom, Shi, Jiye, Lawson, Alastair D. G., Baker, Terry

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The rational design of affinity-attenuated OmCI for the purification of complement C5 by Macpherson, Alex, Liu, Xiaofeng, Dedi, Neesha, Kennedy, Jeffery, Carrington, Bruce, Durrant, Oliver, Heywood, Sam, van den Elsen, Jean, Lawson, Alastair D. G.

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Conservation of Functional Sites on Interleukin-6 and Implications for Evolution of Signaling Complex Assembly and Therapeutic Intervention by Veverka, Vaclav, Baker, Terry, Redpath, Nicholas T., Carrington, Bruce, Muskett, Frederick W., Taylor, Richard J., Lawson, Alastair D. G., Henry, Alistair J., Carr, Mark D.

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Electrostatic interactions modulate the differential aggregation propensities of IgG1 and IgG4P antibodies and inform charged residue substitutions for improved developability by Heads, James T, Lamb, Richard, Kelm, Sebastian, Adams, Ralph, Elliott, Peter, Tyson, Kerry, Topia, Sarfaraj, West, Shauna, Nan, Ruodan, Turner, Alison, Lawson, Alastair D G

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Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F by Adams, Ralph, Maroof, Asher, Baker, Terry, Lawson, Alastair D. G., Oliver, Ruth, Paveley, Ross, Rapecki, Steve, Shaw, Stevan, Vajjah, Pavan, West, Shauna, Griffiths, Meryn

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The proximity of the N- and C- termini of bovine knob domains enable engineering of target specificity into polypeptide chains by Hawkins, Alice, Joyce, Callum, Brady, Kevin, Hold, Adam, Smith, Alan, Knight, Michael, Howard, Conor, van den Elsen, Jean, Lawson, Alastair D.G., Macpherson, Alex

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Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies by Macpherson, Alex, Scott-Tucker, Anthony, Spiliotopoulos, Anastasios, Simpson, Catherine, Staniforth, Justin, Hold, Adam, Snowden, James, Manning, Leah, van den Elsen, Jean, Lawson, Alastair D. G.

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Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F co... by Glatt, Sophie, Baeten, Dominique, Baker, Terry, Griffiths, Meryn, Ionescu, Lucian, Lawson, Alastair D G, Maroof, Ash, Oliver, Ruth, Popa, Serghei, Strimenopoulou, Foteini, Vajjah, Pavan, Watling, Mark I L, Yeremenko, Nataliya, Miossec, Pierre, Shaw, Stevan

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A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF by Lightwood, Daniel J., Munro, Rebecca J., Porter, John, McMillan, David, Carrington, Bruce, Turner, Alison, Scott-Tucker, Anthony, Hickford, Elizabeth S., Schmidt, Antje, Fox, David, Maloney, Alison, Ceska, Tom, Bourne, Tim, O’Connell, James, Lawson, Alastair D. G.

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Conformational Heterogeneity in Antibody-Protein Antigen Recognition: IMPLICATIONS FOR HIGH AFFINITY PROTEIN COMPLEX FORMATION by Addis, Philip W., Hall, Catherine J., Bruton, Shaun, Veverka, Vaclav, Wilkinson, Ian C., Muskett, Frederick W., Renshaw, Philip S., Prosser, Christine E., Carrington, Bruce, Lawson, Alastair D. G., Griffin, Robert, Taylor, Richard J., Waters, Lorna C., Henry, Alistair J., Carr, Mark D.

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Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling by Adams, Ralph, Burnley, Rebecca J., Valenzano, Chiara R., Qureshi, Omar, Doyle, Carl, Lumb, Simon, del Carmen Lopez, Maria, Griffin, Robert, McMillan, David, Taylor, Richard D., Meier, Chris, Mori, Prashant, Griffin, Laura M., Wernery, Ulrich, Kinne, Jörg, Rapecki, Stephen, Baker, Terry S., Lawson, Alastair D. G., Wright, Michael, Ettorre, Anna

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Insights Into the Structure-Function Relationships of Dimeric C3d Fragments by Wahid, Ayla A., Dunphy, Rhys W., Macpherson, Alex, Gibson, Beth G., Kulik, Liudmila, Whale, Kevin, Back, Catherine, Hallam, Thomas M., Alkhawaja, Bayan, Martin, Rebecca L., Meschede, Ingrid, Laabei, Maisem, Lawson, Alastair D. G., Holers, V. Michael, Watts, Andrew G., Crennell, Susan J., Harris, Claire L., Marchbank, Kevin J., van den Elsen, Jean M. H.

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