Ngā hua rapu - Laura Sepp‐Lorenzino

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  1. 1
    A Farnesyl-Protein Transferase Inhibitor Induces p21 Expression and G1 Block in p53 Wild Type Tumor Cells

    A Farnesyl-Protein Transferase Inhibitor Induces p21 Expression and G1 Block in p53 Wild Type Tumor Cells mā Laura Sepp‐Lorenzino, Neal Rosen

    I whakaputaina 1998
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  2. 2
    Expression of Asialoglycoprotein Receptor 1 in Human Hepatocellular Carcinoma

    Expression of Asialoglycoprotein Receptor 1 in Human Hepatocellular Carcinoma mā Bin Shi, Marc Abrams, Laura Sepp‐Lorenzino

    I whakaputaina 2013
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  3. 3
    Inhibition of the proteolytic activity of the multicatalytic proteinase complex (proteasome) by substrate-related peptidyl aldehydes.

    Inhibition of the proteolytic activity of the multicatalytic proteinase complex (proteasome) by substrate-related peptidyl aldehydes. mā Alexander Vinitsky, Christopher Cardozo, Laura Sepp‐Lorenzino, Charlene Michaud, Marian Orłowski

    I whakaputaina 1994
    Whiwhi kuputuhi katoa
    Artigo
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  4. 4
    Herbimycin A Induces the 20 S Proteasome- and Ubiquitin-dependent Degradation of Receptor Tyrosine Kinases

    Herbimycin A Induces the 20 S Proteasome- and Ubiquitin-dependent Degradation of Receptor Tyrosine Kinases mā Laura Sepp‐Lorenzino, Zhengping Ma, David Lebwohl, Alexander Vinitsky, Neal Rosen

    I whakaputaina 1995
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  5. 5
    Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

    Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells. mā Hubert Serve, Nelson S. Yee, Giulia Maria Stella, Laura Sepp‐Lorenzino, James C. Tan, Peter Besmer

    I whakaputaina 1995
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  6. 6
    Micro RNA 145 Targets the Insulin Receptor Substrate-1 and Inhibits the Growth of Colon Cancer Cells

    Micro RNA 145 Targets the Insulin Receptor Substrate-1 and Inhibits the Growth of Colon Cancer Cells mā Bin Shi, Laura Sepp‐Lorenzino, Marco di Prisco, Peter S. Linsley, Tiziana DeAngelis, Renato Baserga

    I whakaputaina 2007
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  7. 7
    Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

    Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90 mā Christine Schneider, Laura Sepp‐Lorenzino, Elmar Nimmesgern, Ouathek Ouerfelli, Samuel J. Danishefsky, Neal Rosen, F. Ulrich Hartl

    I whakaputaina 1996
    Whiwhi kuputuhi katoa
    Artigo
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  8. 8
    A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

    A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells mā Gabriela Chiosis, Merna N. Timaul, Brian S. Lucas, Pamela N. Münster, Fuzhong F. Zheng, Laura Sepp‐Lorenzino, Neal Rosen

    I whakaputaina 2001
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  9. 9
    Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses

    Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses mā Weikang Tao, Xianzhi Mao, Joseph P. Davide, Bruce Ng, Mingmei Cai, Paul A. Burke, Alan B. Sachs, Laura Sepp‐Lorenzino

    I whakaputaina 2010
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  10. 10
    Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver

    Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver mā Weikang Tao, Joseph P. Davide, Mingmei Cai, Guojun Zhang, Victoria J. South, Andrea Matter, Bruce Ng, Ye Zhang, Laura Sepp‐Lorenzino

    I whakaputaina 2010
    Whiwhi kuputuhi katoa
    Artigo
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  11. 11
    Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

    Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage mā Weikang Tao, Victoria J. South, Yun Zhang, Joseph P. Davide, Linda Farrell, Nancy E. Kohl, Laura Sepp‐Lorenzino, Robert B. Lobell

    I whakaputaina 2005
    Whiwhi kuputuhi katoa
    Artigo
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  12. 12
    Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones

    Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones mā Mark M. Moasser, Laura Sepp‐Lorenzino, Nancy E. Kohl, Allen Oliff, Aaron Balog, Dai‐Shi Su, Samuel J. Danishefsky, Neal Rosen

    I whakaputaina 1998
    Whiwhi kuputuhi katoa
    Artigo
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  13. 13
    Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery

    Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery mā Bin Shi, Ed Keough, Andrea Matter, Karen Leander, Stephanie Young, Ed Carlini, Alan B. Sachs, Weikang Tao, Marc Abrams, Bonnie J. Howell, Laura Sepp‐Lorenzino

    I whakaputaina 2011
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  14. 14
    Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth

    Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth mā Tayeba Khan, Hans Weber, Jillian DiMuzio, Andrea Matter, Belma Dogdas, Tosha Shah, Anil Thankappan, Jyoti Disa, Vasant Jadhav, Laura S. Lubbers, Laura Sepp‐Lorenzino, Walter Strapps, Marija Tadin‐Strapps

    I whakaputaina 2016
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  15. 15
    Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment

    Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment mā Marc Abrams, Martin L. Koser, Jessica Seitzer, Stephanie Williams, Martha A. DiPietro, Weimin Wang, Andrew W. Shaw, Xianzhi Mao, Vasant Jadhav, Joseph P. Davide, Paul A. Burke, Alan B. Sachs, Steven M. Stirdivant, Laura Sepp‐Lorenzino

    I whakaputaina 2009
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  16. 16
    Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice

    Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice mā Thomas Michler, Anna D. Kosinska, Julia Festag, Till Bunse, Jinpeng Su, Marc Ringelhan, Hortenzia Imhof, Dirk Grimm, Katja Steiger, Carolin Mogler, Mathias Heikenwälder, Marie-Louise Michel, Carlos A. Guzmán, Stuart Milstein, Laura Sepp‐Lorenzino, Percy A. Knolle, Ulrike Protzer

    I whakaputaina 2020
    Whiwhi kuputuhi katoa
    Artigo
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  17. 17
    Quantitative evaluation of siRNA delivery in vivo

    Quantitative evaluation of siRNA delivery in vivo mā Yi Pei, Paula J. Hancock, Hangchun Zhang, René Bartz, Craig Cherrin, Nathalie Innocent, Colin J. Pomerantz, Jessica Seitzer, Martin L. Koser, Marc Abrams, Yan Xu, Nelly A. Kuklin, Paul A. Burke, Alan B. Sachs, Laura Sepp‐Lorenzino, Stanley F. Barnett

    I whakaputaina 2010
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  18. 18
    Centyrin ligands for extrahepatic delivery of siRNA

    Centyrin ligands for extrahepatic delivery of siRNA mā Donna Klein, Shalom D. Goldberg, Christopher S. Theile, Richard Dambra, Kathleen Haskell, Elise Kuhar, Tricia Lin, Rubina Parmar, Muthiah Manoharan, Mark C. Richter, Mei‐Zhen Wu, Jeannine Mendrola Zarazowski, Vasant Jadhav, Martin A. Maier, Laura Sepp‐Lorenzino, Karyn T. O’Neil, Vadim Dudkin

    I whakaputaina 2021
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  19. 19
    An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo

    An allosteric Akt inhibitor effectively blocks Akt signaling and tumor growth with only transient effects on glucose and insulin levels in vivo mā Craig Cherrin, Kathleen Haskell, Bonnie J. Howell, Raymond C. F. Jones, Karen Leander, R. Robinson, Aubrey Watkins, Mark T. Bilodeau, J. M. HOFFMAN, Philip E.J. Sanderson, George D. Hartman, E. Mahan, Thomayant Prueksaritanont, Guoqiang Jiang, Qing‐Bai She, Neal Rosen, Laura Sepp‐Lorenzino, Deborah Defeo-Jones, Hans E. Huber

    I whakaputaina 2010
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  20. 20
    Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from randomized clinical trials

    Evaluation of RNAi therapeutics VIR-2218 and ALN-HBV for chronic hepatitis B: Results from randomized clinical trials mā Ed Gane, Young‐Suk Lim, Jae Bum Kim, Vasant Jadhav, Ling Shen, Anna I. Bakardjiev, Stephen A. Huang, Andrea L. Cathcart, Florian A. Lempp, Maja M. Janas, Daniel Cloutier, Charalambos Kaittanis, Laura Sepp‐Lorenzino, Gregory Hinkle, Jörg Täubel, Patrick Haslett, Stuart Milstein, Yesseinia I. Angleró-Rodríguez, Christy M. Hebner, Phillip S. Pang, Man‐Fung Yuen

    I whakaputaina 2023
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    Artigo
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