Resultados da pesquisa - Laura J. Sim

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  1. 1
    In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding.

    In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding. Por Laura J. Sim, Dana E. Selley, Steven R. Childers

    Publicado em 1995
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  2. 2
    Cannabinoid CB<sub>1</sub> receptor‐interacting proteins: novel targets for central nervous system drug discovery?

    Cannabinoid CB<sub>1</sub> receptor‐interacting proteins: novel targets for central nervous system drug discovery? Por Tricia H. Smith, Laura J. Sim‐Selley, Dana E. Selley

    Publicado em 2010
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  3. 3
    Effects of Chronic Treatment with Δ<sup>9</sup>-Tetrahydrocannabinol on Cannabinoid-Stimulated [<sup>35</sup>S]GTPγS Autoradiography in Rat Brain

    Effects of Chronic Treatment with Δ<sup>9</sup>-Tetrahydrocannabinol on Cannabinoid-Stimulated [<sup>35</sup>S]GTPγS Autoradiography in Rat Brain Por Laura J. Sim, Robert E. Hampson, Sam A. Deadwyler, Steven R. Childers

    Publicado em 1996
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  4. 4
    Low dose combination of morphine and Δ9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors

    Low dose combination of morphine and Δ9-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors Por Paul A. Smith, Dana E. Selley, Laura J. Sim‐Selley, Sandra P. Welch

    Publicado em 2007
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  5. 5
    Regional enhancement of cannabinoid CB<sub>1</sub> receptor desensitization in female adolescent rats following repeated Δ<sup>9</sup>‐tetrahydrocannabinol exposure

    Regional enhancement of cannabinoid CB<sub>1</sub> receptor desensitization in female adolescent rats following repeated Δ<sup>9</sup>‐tetrahydrocannabinol exposure Por James J. Burston, Jenny L. Wiley, Abimbola A Craig, Dana E. Selley, Laura J. Sim‐Selley

    Publicado em 2010
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  6. 6
    Chronic Heroin Self-Administration Desensitizes μ Opioid Receptor-Activated G-Proteins in Specific Regions of Rat Brain

    Chronic Heroin Self-Administration Desensitizes μ Opioid Receptor-Activated G-Proteins in Specific Regions of Rat Brain Por Laura J. Sim‐Selley, Dana E. Selley, Leslie J. Vogt, Steven R. Childers, Thomas J. Martin

    Publicado em 2000
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  7. 7
    Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy

    Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy Por Katherine W. Falenski, Robert E. Blair, Laura J. Sim‐Selley, Billy R. Martin, Robert J. DeLorenzo

    Publicado em 2007
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  8. 8
    β-Arrestin2 Regulates Cannabinoid CB1 Receptor Signaling and Adaptation in a Central Nervous System Region–Dependent Manner

    β-Arrestin2 Regulates Cannabinoid CB1 Receptor Signaling and Adaptation in a Central Nervous System Region–Dependent Manner Por Peter Nguyen, Cullen L. Schmid, Kirsten M. Raehal, Dana E. Selley, Laura Bohn, Laura J. Sim‐Selley

    Publicado em 2012
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  9. 9
    Chronic ▵<sup>9</sup>‐Tetrahydrocannabinol Treatment Produces a Time‐Dependent Loss of Cannabinoid Receptors and Cannabinoid Receptor‐Activated G Proteins in Rat Brain

    Chronic ▵<sup>9</sup>‐Tetrahydrocannabinol Treatment Produces a Time‐Dependent Loss of Cannabinoid Receptors and Cannabinoid Receptor‐Activated G Proteins in Rat Brain Por C. S. Breivogel, Steven R. Childers, Sam A. Deadwyler, Robert E. Hampson, Leslie J. Vogt, Laura J. Sim‐Selley

    Publicado em 1999
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  10. 10
    Dose-Related Differences in the Regional Pattern of Cannabinoid Receptor Adaptation and in Vivo Tolerance Development to Δ<sup>9</sup>-Tetrahydrocannabinol

    Dose-Related Differences in the Regional Pattern of Cannabinoid Receptor Adaptation and in Vivo Tolerance Development to Δ<sup>9</sup>-Tetrahydrocannabinol Por Diana L. McKinney, Michael P. Cassidy, Lauren Collier, Billy R. Martin, Jenny L. Wiley, Dana E. Selley, Laura J. Sim‐Selley

    Publicado em 2007
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  11. 11
    FAAH−/− Mice Display Differential Tolerance, Dependence, and Cannabinoid Receptor Adaptation After Δ9-Tetrahydrocannabinol and Anandamide Administration

    FAAH−/− Mice Display Differential Tolerance, Dependence, and Cannabinoid Receptor Adaptation After Δ9-Tetrahydrocannabinol and Anandamide Administration Por Katherine W. Falenski, Andrew Thorpe, Joel E. Schlosburg, Benjamin F. Cravatt, Rehab A. Abdullah, Tricia H. Smith, Dana E. Selley, Aron H. Lichtman, Laura J. Sim‐Selley

    Publicado em 2010
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  12. 12
    Mice with Deficiency of G Protein γ<sub>3</sub> Are Lean and Have Seizures

    Mice with Deficiency of G Protein γ<sub>3</sub> Are Lean and Have Seizures Por William F. Schwindinger, Kathryn E. Giger, Kelly S. Betz, Anna M. Stauffer, Elaine M. Sunderlin, Laura J. Sim‐Selley, Dana E. Selley, Sarah K. Bronson, Janet D. Robishaw

    Publicado em 2004
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  13. 13
    Essential role for RGS9 in opiate action

    Essential role for RGS9 in opiate action Por Venetia Zachariou, Dan Georgescu, Nick Sanchez, Zia Ur Rahman, Ralph Dileone, Olivier Berton, Rachael L. Neve, Laura J. Sim‐Selley, Dana E. Selley, Stephen J. Gold, Eric J. Nestler

    Publicado em 2003
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  14. 14
    Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo

    Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo Por Jonathan Z. Long, Daniel K. Nomura, Robert E. Vann, D. Matthew Walentiny, Lamont Booker, Xin Jin, James J. Burston, Laura J. Sim‐Selley, Aron H. Lichtman, Jenny L. Wiley, Benjamin F. Cravatt

    Publicado em 2009
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  15. 15
    Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action

    Metabolic Interplay between Astrocytes and Neurons Regulates Endocannabinoid Action Por Andreu Viader, Jacqueline L. Blankman, Peng Zhong, Xiaojie Liu, Joel E. Schlosburg, Christopher M. Joslyn, Qing-song Liu, Aaron J. Tomarchio, Aron H. Lichtman, Dana E. Selley, Laura J. Sim‐Selley, Benjamin F. Cravatt

    Publicado em 2015
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  16. 16
    Blockade of Endocannabinoid Hydrolytic Enzymes Attenuates Precipitated Opioid Withdrawal Symptoms in Mice

    Blockade of Endocannabinoid Hydrolytic Enzymes Attenuates Precipitated Opioid Withdrawal Symptoms in Mice Por Divya Ramesh, Gracious R. Ross, Joel E. Schlosburg, Robert A. Owens, Rehab A. Abdullah, Steven G. Kinsey, Jonathan Z. Long, Daniel K. Nomura, Laura J. Sim‐Selley, Benjamin F. Cravatt, Hamid I. Akbarali, Aron H. Lichtman

    Publicado em 2011
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  17. 17
    Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice

    Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Sid... Por Sudeshna Ghosh, Steven G. Kinsey, Qing-song Liu, Lenka Hrubá, Lance Richard McMahon, Travis W. Grim, Christina R. Merritt, Laura E. Wise, Rehab A. Abdullah, Dana E. Selley, Laura J. Sim‐Selley, Benjamin F. Cravatt, Aron H. Lichtman

    Publicado em 2015
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  18. 18
    Mutation of Putative GRK Phosphorylation Sites in the Cannabinoid Receptor 1 (CB<sub>1</sub>R) Confers Resistance to Cannabinoid Tolerance and Hypersensitivity to Cannabinoids in Mice

    Mutation of Putative GRK Phosphorylation Sites in the Cannabinoid Receptor 1 (CB<sub>1</sub>R) Confers Resistance to Cannabinoid Tolerance and Hypersensitivity to Cannabinoids in M... Por Daniel J. Morgan, Brian J. Davis, Chris S. Kearn, David J. Marcus, Alex J. Cook, Jim Wager‐Miller, Alex Straiker, Michael H. Myoga, Jeffrey Karduck, Emma Leishman, Laura J. Sim‐Selley, Traci A. Czyzyk, Heather B. Bradshaw, Dana E. Selley, Ken Mackie

    Publicado em 2014
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  19. 19
    Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

    Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system Por Joel E. Schlosburg, Jacqueline L. Blankman, Jonathan Z. Long, Daniel K. Nomura, Bin Pan, Steven G. Kinsey, Peter Nguyen, Divya Ramesh, Lamont Booker, James J. Burston, Elizabeth A. Thomas, Dana E. Selley, Laura J. Sim‐Selley, Qing-song Liu, Aron H. Lichtman, Benjamin F. Cravatt

    Publicado em 2010
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  20. 20
    N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice

    N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice Por Giulia Donvito, Fabiana Piscitelli, Pretal P. Muldoon, Asti Jackson, Rosa Maria Vitale, Enrico D’Aniello, Catia Giordano, Bogna M. Ignatowska‐Jankowska, Mohammed Ahmed Mustafa, Francesca Guida, Gavin N. Petrie, Linda A. Parker, Reem Smoum, Laura J. Sim‐Selley, Sabatino Maione, Aron H. Lichtman, M. Imad Damaj, Vincenzo Di Marzo, Raphael Mechoulam

    Publicado em 2018
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