Resultats de la cerca - Lars Langemeyer

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  1. 1
    Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond

    Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond per Ann-Christin Borchers, Lars Langemeyer, Christian Ungermann

    Publicat 2021
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  2. 2
    A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion

    A guanine nucleotide exchange factor (GEF) limits Rab GTPase–driven membrane fusion per Lars Langemeyer, Angela Perz, Daniel Kümmel, Christian Ungermann

    Publicat 2017
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  3. 3
    Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure

    Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure per Jieqiong Gao, Lars Langemeyer, Daniel Kümmel, Fulvio Reggiori, Christian Ungermann

    Publicat 2018
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  4. 4
    Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code

    Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code per Eric Herrmann, Lars Langemeyer, Kathrin Auffarth, Christian Ungermann, Daniel Kümmel

    Publicat 2023
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  5. 5
    BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor

    BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor per Andreas Gerondopoulos, Lars Langemeyer, Jin Rui Liang, Andrea Linford, Francis A. Barr

    Publicat 2012
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  6. 6
    Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation

    Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation per Lars Langemeyer, Ricardo Bastos, Yiying Cai, Aymelt Itzen, Karin M. Reinisch, Francis A. Barr

    Publicat 2014
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  7. 7
    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1

    Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1 per Stephan Kiontke, Lars Langemeyer, Anne Kuhlee, Saskia Schuback, Stefan Raunser, Christian Ungermann, Daniel Kümmel

    Publicat 2017
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  8. 8
    Multivalent Rab interactions determine tether-mediated membrane fusion

    Multivalent Rab interactions determine tether-mediated membrane fusion per Anna Lürick, Jieqiong Gao, Anne Kuhlee, Erdal Yavavli, Lars Langemeyer, Angela Perz, Stefan Raunser, Christian Ungermann

    Publicat 2016
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  9. 9
    Rab14 and Its Exchange Factor FAM116 Link Endocytic Recycling and Adherens Junction Stability in Migrating Cells

    Rab14 and Its Exchange Factor FAM116 Link Endocytic Recycling and Adherens Junction Stability in Migrating Cells per Andrea Linford, Shin‐ichiro Yoshimura, Ricardo Bastos, Lars Langemeyer, Andreas Gerondopoulos, Daniel J. Rigden, Francis A. Barr

    Publicat 2012
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  10. 10
    Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation

    Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation per Ann-Christin Borchers, Maren Janz, Jan-Hannes Schäfer, Arne Moeller, Daniel Kümmel, Achim Paululat, Christian Ungermann, Lars Langemeyer

    Publicat 2023
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  11. 11
    Structure of the endosomal CORVET tethering complex

    Structure of the endosomal CORVET tethering complex per Dmitry Shvarev, Caroline König, N. Susan, Lars Langemeyer, Stefan Walter, Angela Perz, Florian Fröhlich, Christian Ungermann, Arne Moeller

    Publicat 2024
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  12. 12
    A conserved and regulated mechanism drives endosomal Rab transition

    A conserved and regulated mechanism drives endosomal Rab transition per Lars Langemeyer, Ann-Christin Borchers, Eric Herrmann, Nadia Füllbrunn, Yaping Han, Angela Perz, Kathrin Auffarth, Daniel Kümmel, Christian Ungermann

    Publicat 2020
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  13. 13
    Vps41 functions as a molecular ruler for HOPS tethering complex function

    Vps41 functions as a molecular ruler for HOPS tethering complex function per Caroline König, Dmitry Shvarev, Jieqiong Gao, Ernst ter Haar, Nicole Susan, Kathrin Auffarth, Lars Langemeyer, Arne Moeller, Christian Ungermann

    Publicat 2025
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  14. 14
    Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

    Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery per Dmitry Shvarev, Jannis Schoppe, Caroline König, Angela Perz, Nadia Füllbrunn, Stephan Kiontke, Lars Langemeyer, Dovile Januliene, Kilian Schnelle, Daniel Kümmel, Florian Fröhlich, Arne Moeller, Christian Ungermann

    Publicat 2022
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  15. 15
    TD-60 links RalA GTPase function to the CPC in mitosis

    TD-60 links RalA GTPase function to the CPC in mitosis per Diana Papini, Lars Langemeyer, Maria Alba Abad, Alastair Kerr, Itaru Samejima, Patrick A. Eyers, A. Arockia Jeyaprakash, Jonathan M.G. Higgins, Francis A. Barr, William C. Earnshaw

    Publicat 2015
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  16. 16
    Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

    Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer per Ravi K. Nookala, Lars Langemeyer, A. Pacitto, Bernardo Ochoa‐Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazán, Tom L. Blundell

    Publicat 2012
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  17. 17
    Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering

    Phosphorylation of a membrane curvature–sensing motif switches function of the HOPS subunit Vps41 in membrane tethering per Margarita Cabrera, Lars Langemeyer, Muriel Mari, Ralf Rethmeier, Ioan Orban, Angela Perz, Cornelia Bröcker, Janice Griffith, Daniel Klose, Heinz‐Jürgen Steinhoff, Fulvio Reggiori, Siegfried Engelbrecht-Vandré, Christian Ungermann

    Publicat 2010
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  18. 18
    Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans

    Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans per Ryan P. Liegel, Mark T. Handley, Adam Ronchetti, S.D.M. Brown, Lars Langemeyer, Andrea Linford, Bo Chang, Deborah Morris‐Rosendahl, Sarah M. Carpanini, Renata Posmyk, Verity Harthill, Eamonn Sheridan, Ghada M. H. Abdel‐Salam, Paulien A. Terhal, Francesca Faravelli, Patrizia Accorsi, Lucio Giordano, Lorenzo Pinelli, Britta Hartmann, Allison D. Ebert, Francis A. Barr, Irene A. Aligianis, D.J. Sidjanin

    Publicat 2013
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