Search Results - Larry Rubinstein
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Preclinical Modeling of a Phase 0 Clinical Trial: Qualification of a Pharmacodynamic Assay of Poly (ADP-Ribose) Polymerase in Tumor Biopsies of Mouse Xenografts by Robert J. Kinders, Melinda G. Hollingshead, Sonny Khin, Larry Rubinstein, Joseph E. Tomaszewski, James H. Doroshow, Ralph E. Parchment
Published 2008Artigo -
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Modeling Pharmacodynamic Response to the Poly(ADP-Ribose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells by Jiuping Ji, Robert J. Kinders, Yiping Zhang, Larry Rubinstein, Shivaani Kummar, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow
Published 2011Artigo -
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Application of Molecular Profiling in Clinical Trials for Advanced Metastatic Cancers by Shivaani Kummar, Paul M. Williams, Chih-Jian Lih, Eric C. Polley, A. P. Chen, Larry Rubinstein, Yongmei Zhao, Richard Simon, Barbara A. Conley, James H. Doroshow
Published 2015Artigo -
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Biomarker-driven phase 2 study of MK-2206 and selumetinib (AZD6244, ARRY-142886) in patients with colorectal cancer by T. Khanh, Giovanna Speranza, Rachel Bishop, Sonny Khin, Larry Rubinstein, Robert J. Kinders, Manuel B. Datiles, Michelle Eugeni, Michael Lam, L. Austin Doyle, James H. Doroshow, Shivaani Kummar
Published 2015Artigo -
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Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials by J I Johnson, Shannon Decker, Daniel Zaharevitz, Larry Rubinstein, John M. Venditti, Saul A. Schepartz, Sivaram Kalyandrug, Michaele C. Christian, Susan G. Arbuck, Melinda G. Hollingshead, Edward A. Sausville
Published 2001Artigo -
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Monitoring Drug-Induced γH2AX as a Pharmacodynamic Biomarker in Individual Circulating Tumor Cells by Lihua H. Wang, Thomas D. Pfister, Ralph E. Parchment, Shivaani Kummar, Larry Rubinstein, Yvonne A. Evrard, Martin Gutierrez, Anthony J. Murgo, Joseph E. Tomaszewski, James H. Doroshow, Robert J. Kinders
Published 2010Artigo -
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Development of a Validated Immunofluorescence Assay for γH2AX as a Pharmacodynamic Marker of Topoisomerase I Inhibitor Activity by Robert J. Kinders, Melinda G. Hollingshead, Scott M. Lawrence, Jiuping Ji, Brian Tabb, William M. Bonner, Yves Pommier, Larry Rubinstein, Yvonne A. Evrard, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow
Published 2010Artigo -
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What Can Be Done to Improve Research Biopsy Quality in Oncology Clinical Trials? by Katherine V. Ferry-Galow, Vivekananda Datta, Hala R. Makhlouf, James R. Wright, Bradford J. Wood, Elliot Levy, Etta D. Pisano, Alda L. Tam, Susanna I. Lee, Umar Mahmood, Larry Rubinstein, James H. Doroshow, Alice P. Chen
Published 2018Artigo -
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Modern thirty-day operative mortality for surgical resections in lung cancer by Robert J. Ginsberg, Lucius D. Hill, Robert T. Eagan, Paul Thomas, Clifton F. Mountain, Jean Deslauriers, Willard A. Fry, Ralph O. Butz, Melvyn Goldberg, Paul F. Waters, Donald P. Jones, Peter C. Pairolero, Larry Rubinstein, F. Griffith Pearson
Published 1983Artigo -
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Stage 2 Combination Testing of Rapamycin with Cytotoxic Agents by the Pediatric Preclinical Testing Program by Peter J. Houghton, Christopher L. Morton, Richard Görlick, Richard B. Lock, Hernán Carol, C. Patrick Reynolds, Min H. Kang, John M. Maris, Stephen T. Keir, E. Anders Kolb, Jianrong Wu, Amy Wozniak, Catherine A. Billups, Larry Rubinstein, Malcolm A. Smith
Published 2010Artigo -
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First-in-human study of the epichaperome inhibitor PU-H71: clinical results and metabolic profile by Giovanna Speranza, Larry Anderson, Alice P. Chen, T. Khanh, Michelle Eugeni, Marcie Weil, Larry Rubinstein, Eva Majerová, Jerry M. Collins, Yvonne Horneffer, Lamin Juwara, Jennifer Zlott, Rachel Bishop, Barbara A. Conley, Howard Streicher, Joseph E. Tomaszewski, James H. Doroshow, Shivaani Kummar
Published 2017Artigo -
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National Cancer Institute Breast Cancer Steering Committee Working Group Report on Meaningful and Appropriate End Points for Clinical Trials in Metastatic Breast Cancer by Andrew D. Seidman, Louise Bordeleau, Louis Fehrenbacher, William E. Barlow, Jane Perlmutter, Larry Rubinstein, Suparna Wedam, Dawn L. Hershman, Jennifer Fallas Hayes, Lynn Pearson Butler, Mary Lou Smith, Meredith M. Regan, Julia A. Beaver, Laleh Amiri‐Kordestani, Priya Rastogi, Jo Anne Zujewski, Larissa A. Korde
Published 2018Artigo -
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Analytical Validation and Application of a Targeted Next-Generation Sequencing Mutation-Detection Assay for Use in Treatment Assignment in the NCI-MPACT Trial by Chih-Jian Lih, David Sims, Robin Harrington, Eric C. Polley, Yingdong Zhao, Michele G. Mehaffey, Thomas Forbes, Biswajit Das, William D. Walsh, Vivekananda Datta, Kneshay N. Harper, Courtney H. Bouk, Larry Rubinstein, Richard Simon, Barbara A. Conley, Alice P. Chen, Shivaani Kummar, James H. Doroshow, P. Mickey Williams
Published 2015Artigo -
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A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas by Shivaani Kummar, Jiuping Ji, Robert J. Morgan, Heinz-Josef Lenz, Shannon L. Puhalla, Chandra P. Belani, David R. Gandara, Deborah Allen, Brian F. Kiesel, Jan H. Beumer, Edward M. Newman, Larry Rubinstein, Alice P. Chen, Yiping Zhang, Lihua Wang, Robert J. Kinders, Ralph E. Parchment, Joseph E. Tomaszewski, James H. Doroshow
Published 2012Artigo -
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Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas by Shivaani Kummar, Alice P. Chen, Jiuping Ji, Yiping Zhang, Joel M. Reid, Matthew M. Ames, Lee Jia, Marcie Weil, Giovanna Speranza, Anthony J. Murgo, Robert J. Kinders, Lihua Wang, Ralph E. Parchment, John Carter, Howard Stotler, Larry Rubinstein, Melinda G. Hollingshead, Giovanni Melillo, Yves Pommier, William Bonner, Joseph E. Tomaszewski, James H. Doroshow
Published 2011Artigo
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