Search Results - Lara Wahlster

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  1. 1
    Molecular chaperones and protein folding as therapeutic targets in Parkinson’s disease and other synucleinopathies

    Molecular chaperones and protein folding as therapeutic targets in Parkinson’s disease and other synucleinopathies by Darius Ebrahimi‐Fakhari, Laiq-Jan Saidi, Lara Wahlster

    Published 2013
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  2. 2
    Molecular Chaperones in Parkinson's Disease – Present and Future

    Molecular Chaperones in Parkinson's Disease – Present and Future by Darius Ebrahimi‐Fakhari, Lara Wahlster, Pamela J. McLean

    Published 2011
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  3. 3
    Protein degradation pathways in Parkinson’s disease: curse or blessing

    Protein degradation pathways in Parkinson’s disease: curse or blessing by Darius Ebrahimi‐Fakhari, Lara Wahlster, Pamela J. McLean

    Published 2012
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  4. 4
    Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases

    Emerging role of autophagy in pediatric neurodegenerative and neurometabolic diseases by Darius Ebrahimi‐Fakhari, Lara Wahlster, Georg F. Hoffmann, Stefan Kölker

    Published 2013
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  5. 5
    COVID‐19 presenting with autoimmune hemolytic anemia in the setting of underlying immune dysregulation

    COVID‐19 presenting with autoimmune hemolytic anemia in the setting of underlying immune dysregulation by Lara Wahlster, Nina Weichert‐Leahey, Maria Trissal, Rachael F. Grace, Vijay G. Sankaran

    Published 2020
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  6. 6
    Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer’s disease

    Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer’s disease by Lara Wahlster, Muriel Arimon, Navine Nasser‐Ghodsi, Kathryn Leigh Post, Alberto Serrano‐Pozo, Kengo Uemura, Oksana Berezovska

    Published 2012
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  7. 7
    Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism

    Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism by Darius Ebrahimi‐Fakhari, Afshin Saffari, Lara Wahlster, Jenny Lu, Susan Byrne, Georg F. Hoffmann, Heinz Jungbluth, Mustafa Şahin

    Published 2015
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  8. 8
    Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells

    Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells by Darius Ebrahimi‐Fakhari, Lara Wahlster, Fabian Bartz, Jennifer Werenbeck-Ueding, Maria Praggastis, Jessie Zhang, Brigitte Joggerst-Thomalla, Susanne Theiß, Dirk Grimm, Daniel S. Ory, Heiko Runz

    Published 2016
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  9. 9
    A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia

    A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia by Richard A. Voit, Liming Tao, Fulong Yu, Liam D. Cato, Blake Cohen, Travis J. Fleming, Mateusz Antoszewski, Xiaotian Liao, Claudia Fiorini, Satish K. Nandakumar, Lara Wahlster, Kristian Teichert, Aviv Regev, Vijay G. Sankaran

    Published 2022
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  10. 10
    Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex

    Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex by Darius Ebrahimi‐Fakhari, Afshin Saffari, Lara Wahlster, Alessia Di Nardo, Daria Turner, Tommy L. Lewis, Christopher Conrad, Jonathan M. Rothberg, Jonathan O. Lipton, Stefan Kölker, Georg F. Hoffmann, Min‐Joon Han, Franck Polleux, Mustafa Şahin

    Published 2016
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  11. 11
    A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development

    A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development by Marcella Cesana, Michael H. Guo, Davide Cacchiarelli, Lara Wahlster, Jessica Barragan, Sergei Doulatov, Linda T. Vo, Beatrice Salvatori, Cole Trapnell, Kendell Clement, Patrick Cahan, Kaloyan M. Tsanov, Patricia Sousa, Bárbara Tazón‐Vega, Adriano Bolondi, Federico M. Giorgi, Andrea Califano, John L. Rinn, Alexander Meissner, Joel N. Hirschhorn, George Q. Daley

    Published 2018
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  12. 12
    High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia

    High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia by Afshin Saffari, Barbara Brechmann, Cedric Böger, Wardiya Afshar Saber, Hellen Jumo, Dosh Whye, Delaney Wood, Lara Wahlster, Julian E. Alecu, M. L. ZIEGLER, Marlene Scheffold, Kellen D. Winden, Jed L. Hubbs, Elizabeth D. Buttermore, Lee Barrett, Georg H. H. Borner, Alexandra K. Davies, Darius Ebrahimi‐Fakhari, Mustafa Şahin

    Published 2024
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  13. 13
    Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia

    Regulated GATA1 expression as a universal gene therapy for Diamond-Blackfan anemia by Richard A. Voit, Xiaotian Liao, Alexis Caulier, Mateusz Antoszewski, Blake Cohen, Myriam Armant, Henry Y. Lu, Travis J. Fleming, Elena Kamal, Lara Wahlster, Aoife M. Roche, J.K. Everett, Angelina Petrichenko, Meimei Huang, William T. Clarke, Kasiani C. Myers, Craig M. Forester, Antonio R. Pérez‐Atayde, Frederic D. Bushman, Danilo Pellin, Akiko Shimamura, David A. Williams, Vijay G. Sankaran

    Published 2024
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  14. 14
    Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors

    Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors by Sergei Doulatov, Linda T. Vo, Elizabeth R. Macari, Lara Wahlster, Melissa A. Kinney, Alison M. Taylor, Jessica Barragan, Manav Gupta, Katherine McGrath, Hsiang‐Ying Lee, Jessica M. Humphries, Alexander L. DeVine, Anupama Narla, Blanche P. Alter, Alan H. Beggs, Suneet Agarwal, Benjamin L. Ebert, Hanna T. Gazda, Harvey F. Lodish, Colin A. Sieff, Thorsten M. Schlaeger, Leonard I. Zon, George Q. Daley

    Published 2017
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  15. 15
    A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children

    A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children by Adam J. de Smith, Lara Wahlster, Soyoung Jeon, Linda Kachuri, Susan Black, Jalen Langie, Liam D. Cato, Nathan Nakatsuka, Tsz-Fung Chan, Guangze Xia, Soumyaa Mazumder, Wenjian Yang, Steven Gazal, Celeste Eng, Donglei Hu, Esteban G. Burchard, Elad Ziv, Catherine Metayer, Nicholas Mancuso, Jun J. Yang, Xiaomei Ma, Joseph L. Wiemels, Fulong Yu, Charleston W. K. Chiang, Vijay G. Sankaran

    Published 2024
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  16. 16
    Massively parallel base editing to map variant effects in human hematopoiesis

    Massively parallel base editing to map variant effects in human hematopoiesis by Jorge D. Martin-Rufino, Nicole Castano, Michael Pang, Emanuelle I. Grody, Samantha R. Joubran, Alexis Caulier, Lara Wahlster, Tongqing Li, Xiaojie Qiu, Anna Maria Riera-Escandell, Gregory A. Newby, Aziz Al’Khafaji, Santosh Kumar Chaudhary, Susan Black, Chen Weng, Glen Munson, David R. Liu, Marcin W. Włodarski, Kacie Sims, Jamie H. Oakley, Ross M. Fasano, Ramnik J. Xavier, Eric S. Lander, Daryl E. Klein, Vijay G. Sankaran

    Published 2023
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  17. 17
    Deciphering cell states and genealogies of human haematopoiesis

    Deciphering cell states and genealogies of human haematopoiesis by Chen Weng, Fulong Yu, Dian Yang, Michael Poeschla, L. Alexander Liggett, Matthew G. Jones, Xiaojie Qiu, Lara Wahlster, Alexis Caulier, Jeffrey A. Hussmann, Alexandra Schnell, Kathryn E. Yost, Luke W. Koblan, Jorge D. Martin-Rufino, Kyung Hoi Min, Alessandro Hammond, Daniel Ssozi, Raphael Bueno, Hari R. Mallidi, Antonia Kreso, Javier Escabi, William M. Rideout, Tyler Jacks, Sahand Hormoz, Peter van Galen, Jonathan S. Weissman, Vijay G. Sankaran

    Published 2024
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