Rezultaty - Lara Bossini‐Castillo

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  1. 1
    Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

    Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases od Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Wendy C. Rowan, Nikolina Nakić, Jorge Esparza-Gordillo, Lara Bossini‐Castillo, David F. Tough, Christopher Larminie, Paola G. Bronson, David Willé, Gosia Trynka

    Wydane 2019
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  2. 2
    Immune disease variants modulate gene expression in regulatory CD4+ T cells

    Immune disease variants modulate gene expression in regulatory CD4+ T cells od Lara Bossini‐Castillo, Dafni A. Glinos, Natalia Kunowska, Gosia Golda, Abigail Lamikanra, Michaela Spitzer, Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Claire Cattermole, Kaur Alasoo, Alice Mann, Kousik Kundu, Anna Lorenc, Nicole Soranzo, Ian Dunham, David J. Roberts, Gosia Trynka

    Wydane 2022
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  3. 3
    Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation

    Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation od Blagoje Soskic, Eddie Cano-Gamez, Deborah J. Smyth, Kirsty Ambridge, Ziying Ke, Julie C. Matte, Lara Bossini‐Castillo, Joanna Kaplanis, Lucia Ramirez-Navarro, Anna Lorenc, Nikolina Nakić, Jorge Esparza-Gordillo, Wendy C. Rowan, David Willé, David F. Tough, Paola G. Bronson, Gosia Trynka

    Wydane 2022
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  4. 4
    <i>IRF5</i>polymorphism predicts prognosis in patients with systemic sclerosis

    <i>IRF5</i>polymorphism predicts prognosis in patients with systemic sclerosis od Roozbeh Sharif, Maureen D. Mayes, Filemon K. Tan, Olga Y. Gorlova, Laura K. Hummers, Ami A. Shah, Daniel E. Furst, Dinesh Khanna, Javier Martı́n, Lara Bossini‐Castillo, Emilio B. González, Binwu Ying, Hilda T. Draeger, Sandeep K. Agarwal, John D. Reveille, Frank C. Arnett, Fredrick M. Wigley, Shervin Assassi

    Wydane 2012
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  5. 5
    Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

    Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk od Jennie G. Pouget, Buhm Han, Yang Wu, Emmanuel Mignot, Hanna M. Ollila, Juliet N. Barker, Sarah L. Spain, Nick Dand, Richard C. Trembath, Javier Martı́n, Maureen D. Mayes, Lara Bossini‐Castillo, Elena López‐Isac, Ying Jin, Stephanie A. Santorico, Richard A. Spritz, Hákon Hákonarson, Constantin Polychronakos, Soumya Raychaudhuri, Jo Knight

    Wydane 2019
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  6. 6
    Gene expression variability across cells and species shapes innate immunity

    Gene expression variability across cells and species shapes innate immunity od Tzachi Hagai, Xi Chen, Ricardo J. Miragaia, Raghd Rostom, Tomás Gomes, Natalia Kunowska, Johan Henriksson, Jong-Eun Park, Valentina Proserpio, Giacomo Donati, Lara Bossini‐Castillo, Felipe A. Vieira Braga, Guy Naamati, James Fletcher, Emily Stephenson, Péter Végh, Gosia Trynka, Ivanela Kondova, Mike Dennis, Muzlifah Haniffa, Armita Nourmohammad, Michael Lässig, Sarah A. Teichmann

    Wydane 2018
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  7. 7
    A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells

    A distal enhancer at risk locus 11q13.5 promotes suppression of colitis by Treg cells od Rabab Nasrallah, Charlotte J. Imianowski, Lara Bossini‐Castillo, Francis M. Grant, Mikail Dogan, Lindsey Placek, Lina Kozhaya, Paula Kuo, Firas Sadiyah, Sarah K. Whiteside, Maxwell R. Mumbach, Dafni A. Glinos, Panagiota Vardaka, Carly E. Whyte, Teresa Lozano, Toshitsugu Fujita, Hodaka Fujii, Adrian Liston, Simon Andrews, Adeline Cozzani, Jie Yang, Suman Mitra, Enrico Lugli, Howard Y. Chang, Derya Unutmaz, Gosia Trynka, Rahul Roychoudhuri

    Wydane 2020
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  8. 8
    A rare polymorphism in the gene for Toll‐like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

    A rare polymorphism in the gene for Toll‐like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators od J. C. A. Broen, Lara Bossini‐Castillo, L. van Bon, Madelon C Vonk, H. Knaapen, Lorenzo Beretta, Blanca Rueda‐Medina, Roger Hesselstrand, Ariane L. Herrick, Jane Worthington, N. Hunzelman, Christopher P. Denton, Carmen Fonseca, Gabriela Riemekasten, H. Kiener, R Scorza, Carmen Pilar Simeón‐Aznar, Norberto Ortego‐Centeno, Miguel Á. González‐Gay, Paolo Airò, Marieke J. H. Coenen, Javier Martı́n, Timothy R. D. J. Radstake

    Wydane 2011
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  9. 9
    Influence of<i>TYK2</i>in systemic sclerosis susceptibility: a new<i>locus</i>in the IL-12 pathway

    Influence of<i>TYK2</i>in systemic sclerosis susceptibility: a new<i>locus</i>in the IL-12 pathway od Elena López‐Isac, Diana Campillo-Davó, Lara Bossini‐Castillo, Sandra G. Guerra, Shervin Assassi, Carmen Pilar Simeón‐Aznar, Patrícia Carreira, Norberto Ortego‐Centeno, Paloma García de la Peña, Lorenzo Beretta, Alessandro Santaniello, Chiara Bellocchi, Claudio Lunardi, Gianluca Moroncini, Tianlu Li, Gabriela Riemekasten, Torsten Witte, Nicolas Hunzelmann, Alexander Kreuter, Jörg H. W. Distler, Alexandre E. Voskuyl, Jeska de Vries‐Bouwstra, Ariane L. Herrick, Jane Worthington, Christopher P. Denton, Carmen Fonseca, Timothy R. D. J. Radstake, Maureen D. Mayes, Javier Martı́n

    Wydane 2015
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  10. 10
    A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility

    A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility od Elena López‐Isac, Lara Bossini‐Castillo, Carmen Pilar Simeón‐Aznar, María Victoria Egurbide, Juan José Alegre Sancho, José Luis Callejas‐Rubio, José Andrés Román‐Ivorra, M. Freire, Lorenzo Beretta, Alessandro Santaniello, Paolo Airò, Claudio Lunardi, Nicolas Hunzelmann, Gabriela Riemekasten, Torsten Witte, Alexander Kreuter, Jörg H. W. Distler, Annemie J. Schuerwegh, Madelon C Vonk, Alexandre E. Voskuyl, Paul G. Shiels, Jacob M. van Laar, Carmen Fonseca, Christopher P. Denton, Ariane L. Herrick, Jane Worthington, Shervin Assassi, Bobby P. C. Koeleman, Maureen D. Mayes, Timothy R. D. J. Radstake, Javier Martı́n

    Wydane 2014
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  11. 11
    Confirmation of<i>TNIP1</i>but not<i>RHOB</i>and<i>PSORS1C1</i>as systemic sclerosis risk factors in a large independent replication study

    Confirmation of<i>TNIP1</i>but not<i>RHOB</i>and<i>PSORS1C1</i>as systemic sclerosis risk factors in a large independent replication study od Lara Bossini‐Castillo, José-Ezequiel Martín, Jasper Broen, Carmen Pilar Simeón‐Aznar, Lorenzo Beretta, Olga Y. Gorlova, Madelon C Vonk, Norberto Ortego‐Centeno, Gerard Espinosa, Patrícia Carreira, Paloma García de la Peña, N. Oreiro, José Andrés Román-Ivorra, María Jesús Castillo, Miguel Á. González‐Gay, Luis Sáez‐Comet, I. Castellví, Annemie J. Schuerwegh, Alexandre E. Voskuyl, Anna‐Maria Hoffmann‐Vold, Roger Hesselstrand, Annica Nordin, Claudio Lunardi, R Scorza, Jacob M. van Laar, Paul G. Shiels, Ariane L. Herrick, Jane Worthington, Carmen Fonseca, Christopher P. Denton, Filemon K. Tan, Frank C. Arnett, Shervin Assassi, Bobby P. C. Koeleman, Maureen D. Mayes, Timothy R. D. J. Radstake, Javier Martı́n

    Wydane 2012
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  12. 12
    A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

    A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations od Lara Bossini‐Castillo, José-Ezequiel Martín, Jasper Broen, Olga Y. Gorlova, Carmen Pilar Simeón‐Aznar, Lorenzo Beretta, Madelon C Vonk, José Luís Callejas-Rubio, I. Castellví, Patrícia Carreira, Francisco José García Hernández, M. Fernández Castro, Marieke J. H. Coenen, Gabriela Riemekasten, Torsten Witte, Nicolas Hunzelmann, Alexander Kreuter, Jörg H. W. Distler, Bobby P. C. Koeleman, Alexandre E. Voskuyl, Annemie J. Schuerwegh, Øyvind Palm, Roger Hesselstrand, Annica Nordin, Paolo Airò, Claudio Lunardi, R Scorza, Paul G. Shiels, Jacob M. van Laar, Ariane L. Herrick, Jane Worthington, Christopher P. Denton, Filemon K. Tan, Frank C. Arnett, Sandeep Agarwal, Shervin Assassi, Carmen Fonseca, Maureen D. Mayes, Timothy R. D. J. Radstake, Javier Martı́n

    Wydane 2011
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  13. 13
    A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides

    A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides od Lara Bossini‐Castillo, Carolien G. F. de Kovel, Henrik Källberg, Ruben van ‘t Slot, Annet Italiaander, Marieke J. H. Coenen, Paul P. Tak, Marcel D. Posthumus, Cisca Wijmenga, T. Huizinga, Annette H M van der Helm–van Mil, Gerrie Stoeken‐Rijsbergen, Luis Rodríguez‐Rodríguez, Alejandro Balsa, Isidoro González‐Álvaro, Miguel Á. González‐Gay, Carmen Gómez‐Vaquero, Barbara Franke, Sita H. Vermeulen, IE van der Horst-Bruinsma, Ben A. C. Dijkmans, Gertjan Wolbink, Roel A. Ophoff, Marthe T. Mæhlen, Piet L. C. M. van Riel, Marilyn E. Merriman, Lars Klareskog, Benedicte A. Lie, Tony R. Merriman, J. Bart A. Crusius, Elisabeth Brouwer, Javier Martı́n, Niek de Vries, René E. M. Toes, Leonid Padyukov, Bobby P. C. Koeleman

    Wydane 2014
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  14. 14
    A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort

    A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort od Lara Bossini‐Castillo, Jasper Broen, Carmen Pilar Simeón‐Aznar, Lorenzo Beretta, Madelon C Vonk, Norberto Ortego‐Centeno, Gerard Espinosa, Patrícia Carreira, María Teresa Camps, Nuria Navarrete Navarrete, María Francisca González‐Escribano, Esther F. Vicente‐Rabaneda, Luis Rodríguez‐Rodríguez, Carlos Tolosa, José Andrés Román-Ivorra, Inmaculada Gómez-Gracia, Francisco José García Hernández, I. Castellví, Maria E. Gallego, Antonio Fernández‐Nebro, Rosa García-Portales, María Victoria Egurbide, V Fonollosa, Paloma García de la Peña, A. Pros, Miguel Á. González‐Gay, Roger Hesselstrand, Gabriela Riemekasten, Torsten Witte, Marieke J. H. Coenen, Bobby P. C. Koeleman, Frédéric Houssiau, Vanessa Smith, Filip De Keyser, René Westhovens, Ellen De Langhe, Alexandre E. Voskuyl, Annemie J. Schuerwegh, Meng May Chee, Rajan Madhok, Paul G. Shiels, Carmen Fonseca, Christopher P. Denton, Kathleen Claes, Leonid Padykov, Annica Nordin, Øyvind Palm, Benedicte A. Lie, Paolo Airò, R Scorza, Jacob M. van Laar, Nicolas Hunzelmann, Alexander Kreuter, Ariane L. Herrick, Jane Worthington, Timothy R. D. J. Radstake, Javier Martı́n, Blanca Rueda‐Medina

    Wydane 2010
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  15. 15
    Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets od Louise V. Wain, Nick Shrine, María Soler Artigas, A. Mesut Erzurumluoglu, Boris Noyvert, Lara Bossini‐Castillo, Ma’en Obeidat, Amanda P. Henry, Michael A. Portelli, Robert J. Hall, Charlotte K. Billington, Tracy L. Rimington, Anthony G. Fenech, Catherine John, Tineka Blake, Victoria E. Jackson, Richard J. Allen, Bram P. Prins, Archie Campbell, David J. Porteous, Marjo‐Riitta Järvelin, Matthias Wielscher, Anthony James, Jennie Hui, Nicholas J. Wareham, Wei Zhao, James F. Wilson, Peter K. Joshi, Beate Stubbe, Rajesh Rawal, Holger Schulz, Medea Imboden, Nicole Probst‐Hensch, Stefan Karrasch, Christian Gieger, Ian J. Deary, Sarah E. Harris, Jonathan Marten, Igor Rudan, Stefan Enroth, Ulf Gyllensten, Shona M. Kerr, Ozren Polašek, Mika Kähönen, Ida Surakka, Véronique Vitart, Caroline Hayward, Terho Lehtimäki, Olli T. Raitakari, David M. Evans, Alex Henderson, Craig E. Pennell, Carol A. Wang, Peter D. Sly, Emily S. Wan, Robert Busch, Brian D. Hobbs, Augusto A. Litonjua, David Sparrow, Amund Gulsvik, Per Bakke, James D. Crapo, Terri H. Beaty, Nadia N. Hansel, Rasika A. Mathias, Ingo Ruczinski, Kathleen C. Barnes, Yohan Bossé, Philippe Joubert, Maarten van den Berge, Corry‐Anke Brandsma, Peter D. Paré, Don D. Sin, David C. Nickle, Ke Hao, Omri Gottesman, Frederick E. Dewey, Shannon Bruse, David J. Carey, H. Lester Kirchner, Stefan Jonsson, Guðmar Þorleifsson, Ingileif Jónsdóttir, Þórarinn Gíslason, Kāri Stefánsson, Claudia Schurmann, Girish N. Nadkarni, Erwin P. Böttinger, Ruth J. F. Loos, Robin Walters, Zhengming Chen, Iona Y. Millwood, Julien Vaucher, Om Kurmi, Liming Li, Anna Hansell, Christopher E. Brightling, Eleftheria Zeggini, Michael H. Cho, Edwin K. Silverman

    Wydane 2017
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  16. 16
    Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis

    Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis od Maureen D. Mayes, Lara Bossini‐Castillo, Olga Y. Gorlova, José-Ezequiel Martín, Xiaodong Zhou, Wei V. Chen, Shervin Assassi, Binwu Ying, Filemon K. Tan, Frank C. Arnett, John D. Reveille, Sandra G. Guerra, María Teruel, F. David Carmona, Peter K. Gregersen, Annette T. Lee, Elena López‐Isac, Eguzkine Ochoa, Patrícia Carreira, Carmen Pilar Simeón‐Aznar, I. Castellví, Miguel Á. González‐Gay, Alexandra Zhernakova, Leonid Padyukov, Marta E. Alarcón‐Riquelme, Cisca Wijmenga, Matthew A. Brown, Lorenzo Beretta, Gabriela Riemekasten, Torsten Witte, Nicolas Hunzelmann, Alexander Kreuter, Jörg H. W. Distler, Alexandre E. Voskuyl, Annemie J. Schuerwegh, Roger Hesselstrand, Annica Nordin, Paolo Airò, Claudio Lunardi, Paul G. Shiels, Jacob M. van Laar, Ariane L. Herrick, Jane Worthington, Christopher P. Denton, Fredrick M. Wigley, Laura K. Hummers, John Varga, Monique Hinchcliff, Murray Baron, Marie Hudson, Janet Pope, Daniel E. Furst, Dinesh Khanna, Kristin Phillips, Elena Schiopu, Barbara Segal, Jerry A. Molitor, Richard M. Silver, Virginia Steen, Robert W. Simms, Robert Lafyatis, Barri J. Fessler, Tracy Frech, Firas Alkassab, Peter Docherty, Elżbieta Kamińska, Nader Khalidi, Henry Niall Jones, Janet Markland, David Robinson, Jasper Broen, Timothy R. D. J. Radstake, Carmen Fonseca, Bobby P. C. Koeleman, Javier Martı́n, Norberto Ortego‐Centeno, Raquel Ríos, José Luís Callejas-Rubio, Nuria Navarrete Navarrete, Rosa García Portales, María Teresa Camps, Antonio Fernández‐Nebro, María Francisca González‐Escribano, Julio Sánchez-Román, Francisco José García Hernández, María Jesús Castillo, M. Á. Aguirre, Inmaculada Gómez-Gracia, Benjamín Fernández‐Gutiérrez, Luis Rodríguez‐Rodríguez, Esther Vicente, José Luís Andreu, M. Fernández Castro, Paloma García de la Peña, Francisco Javier López-Longo, L. Martínez, V Fonollosa, Gerard Espinosa, Carlos Tolosa, A. Pros

    Wydane 2014
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  17. 17
    A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility

    A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility od F. David Carmona, Sarah Mackie, José-Ezequiel Martín, John Taylor, Augusto Vaglio, Stephen Eyre, Lara Bossini‐Castillo, Santos Castañeda, María C. Cid, José Hernández‐Rodríguez, Sergio Prieto‐González, Roser Solans, Marc Ramentol-Sintas, Marı́a-Francisca González-Escribano, Lourdes Ortiz‐Fernández, Inmaculada C. Morado, Javier Narváez, José A. Miranda‐Filloy, Lorenzo Beretta, Claudio Lunardi, Marco A. Cimmino, Davide Gianfreda, Daniele Santilli, Giuseppe A. Ramirez, Alessandra Soriano, Francesco Muratore, Giulia Pazzola, Olga Addimanda, Cisca Wijmenga, Torsten Witte, Jan Henrik Schirmer, Frank Moosig, Verena Schönau, André Franke, Øyvind Palm, Øyvind Molberg, Andreas P. Diamantopoulos, Simon Carette, David Cuthbertson, Lindsy Forbess, Gary S. Hoffman, Nader Khalidi, Curry L. Koening, Carol A. Langford, Carol A. McAlear, Larry W. Moreland, Paul A. Monach, Christian Pagnoux, Philip Seo, Robert Spiera, Antoine G. Sreih, Kenneth J. Warrington, Steven R. Ytterberg, Peter K. Gregersen, Colin Pease, Andrew Gough, Michael R. Green, Lesley Hordon, Stephen Jarrett, Richard A. Watts, Sarah Levy, Yusuf Patel, Sanjeet Kamath, Bhaskar DasGupta, Jane Worthington, Bobby P. C. Koeleman, Paul I. W. de Bakker, Jennifer H. Barrett, Carlo Salvarani, Peter A. Merkel, Miguel Á. González‐Gay, Ann W. Morgan, Javier Martı́n, Agustín Martínez-Berriochoa, Ainhoa Unzurrunzaga, Ana Hidalgo-Conde, Ana Belén Madroñero-Vuelta, Antonio Fernández‐Nebro, M. Carmen Ordóñez-Cañizares, B. Escalante, Begoña Marí-Alfonso, B. Sopeña, César Magro‐Checa, Enrique Raya, Elena Grau, José A. Ruiz San Román, Eugenio de Miguel, FJ López-Longo, Lina Martínez, Carmen Gómez‐Vaquero, Benjamín Fernández‐Gutiérrez, Luis Rodríguez‐Rodríguez, J. Bernardino Díaz-López, Luis Caminal‐Montero, Aleida Martínez Zapico, Jordi Monfort, Laura Tío, Julio Sánchez-Martín, Juan José Alegre Sancho, Luis Sáez‐Comet

    Wydane 2015
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  18. 18
    GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

    GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways od Elena López‐Isac, Marialbert Acosta‐Herrera, Martin Kerick, Shervin Assassi, Ansuman T. Satpathy, Jeffrey M. Granja, Maxwell R. Mumbach, Lorenzo Beretta, Carmen Pilar Simeón‐Aznar, Patrícia Carreira, Norberto Ortego‐Centeno, I. Castellví, Lara Bossini‐Castillo, F. David Carmona, Gisela Orozco, Nicolas Hunzelmann, Jörg H. W. Distler, André Franke, Claudio Lunardi, Gianluca Moroncini, Tianlu Li, Jeska de Vries‐Bouwstra, Cisca Wijmenga, Bobby P. C. Koeleman, Annika Nordin, Leonid Padyukov, Anna‐Maria Hoffmann‐Vold, Benedicte A. Lie, Raimon Rios, José Luís Callejas-Rubio, José Antonio Vargas‐Hitos, Rosa García-Portales, M T Camps, Antonio Fernández‐Nebro, Marı́a-Francisca González-Escribano, Francisco José García Hernández, María Jesús Castillo, M. Á. Aguirre, Inmaculada Gómez-Gracia, Benjamín Fernández‐Gutiérrez, Luis Rodríguez‐Rodríguez, Paloma García de la Peña, Esther Vicente, José Luís Andreu, M. Fernández Castro, Francisco Javier López-Longo, Leticia Quintanilla Martinez, Fonollosa, Alberto Guillén, Gerard Espinosa, Carlos Tolosa, A. Pros, Mónica Rodríguez‐Carballeira, Javier Narváez, Manuel Rubio‐Rivas, Vera Ortiz-Santamaría, Ana Belén Madroñero, Miguel Á. González‐Gay, Bianca J. Diaz, Luis Trapiella, André M. M. Sousa, M. V. Egurbide, P. Fanlo-Mateo, Luis Sáez‐Comet, Fidel Díez Díaz, Hernández, E. Beltrán, José Andrés Román-Ivorra, Elena Grau, Juan José Alegre Sancho, M. Freire, Francisco J. Blanco, N. Oreiro, Torsten Witte, Alexander Kreuter, G. Riemekasten, Paolo Airò, César Magro‐Checa, Alexandre E. Voskuyl, Madelon C Vonk, Roger Hesselstrand, Susanna Proudman, Wendy Stevens, Mandana Nikpour, Jane Zochling, J. Sahhar, Janet Roddy, Peter Nash, Kathleen Tymms, Maureen Rischmueller, Sue Lester, Timothy J. Vyse, Ariane L. Herrick, Jane Worthington, Christopher P. Denton, Yannick Allanore, Matthew A. Brown, Timothy R. D. J. Radstake, Carmen Fonseca, Howard Y. Chang

    Wydane 2019
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