Canlyniadau Chwilio - Laleu, Benoît

Screening a repurposing library, the Medicines for Malaria Venture Stasis Box, against Schistosoma mansoni gan Pasche, Valérian, Laleu, Benoît, Keiser, Jennifer

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Screening of TB Actives for Activity against Nontuberculous Mycobacteria Delivers High Hit Rates gan Low, Jian Liang, Wu, Mu-Lu, Aziz, Dinah Binte, Laleu, Benoît, Dick, Thomas

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Actives from MMV Open Access Boxes? A suggested way forward gan Samby, Kirandeep, Willis, Paul A., Burrows, Jeremy N., Laleu, Benoît, Webborn, Peter J. H.

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Screening of the ‘Pathogen Box’ identifies an approved pesticide with major anthelmintic activity against the barber's pole worm gan Preston, Sarah, Jiao, Yaqing, Jabbar, Abdul, McGee, Sean L., Laleu, Benoît, Willis, Paul, Wells, Timothy N.C., Gasser, Robin B.

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Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development gan Manickam, Yogavel, Malhotra, Nipun, Mishra, Siddhartha, Babbar, Palak, Dusane, Abhishek, Laleu, Benoît, Bellini, Valeria, Hakimi, Mohamed-Ali, Bougdour, Alexandre, Sharma, Amit

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Nicotinamide Adenine Dinucleotide Phosphate Oxidase (NOX) in Experimental Liver Fibrosis: GKT137831 as a Novel Potential Therapeutic Agent gan Aoyama, Tomonori, Paik, Yong-Han, Watanabe, Sumio, Laleu, Benoît, Gaggini, Francesca, Fioraso-Cartier, Laetitia, Molango, Sophie, Heitz, Freddy, Merlot, Cédric, Szyndralewiez, Cédric, Page, Patrick, Brenner, David A.

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Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma gan Lim, Wilson, Melse, Youri, Konings, Mickey, Phat Duong, Hung, Eadie, Kimberly, Laleu, Benoît, Perry, Benjamin, Todd, Matthew H., Ioset, Jean-Robert, van de Sande, Wendy W. J.

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Piperidine-4-Carboxamides Target DNA Gyrase in Mycobacterium abscessus gan Negatu, Dereje Abate, Beuchel, Andreas, Madani, Abdeldjalil, Alvarez, Nadine, Chen, Chao, Aragaw, Wassihun Wedajo, Zimmerman, Matthew D., Laleu, Benoît, Gengenbacher, Martin, Dartois, Véronique, Imming, Peter, Dick, Thomas

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Escaping from Flatland: Antimalarial Activity of sp(3)-Rich Bridged Pyrrolidine Derivatives gan Cox, Brian, Duffy, James, Zdorichenko, Victor, Bellanger, Corentin, Hurcum, Jessica, Laleu, Benoît, Booker-Milburn, Kevin I., Elliott, Luke D., Robertson-Ralph, Michael, Swain, Christopher J., Bishop, Stephen J., Hallyburton, Irene, Anderson, Mark

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Susceptibility Testing of Medically Important Parasites gan Genetu Bayih, Abebe, Debnath, Anjan, Mitre, Edward, Huston, Christopher D., Laleu, Benoît, Leroy, Didier, Blasco, Benjamin, Campo, Brice, Wells, Timothy N. C., Willis, Paul A., Sjö, Peter, Van Voorhis, Wesley C., Pillai, Dylan R.

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Screening of the ‘Stasis Box’ identifies two kinase inhibitors under pharmaceutical development with activity against Haemonchus contortus gan Jiao, Yaqing, Preston, Sarah, Koehler, Anson V., Stroehlein, Andreas J., Chang, Bill C. H., Simpson, Kaylene J., Cowley, Karla J., Palmer, Michael J., Laleu, Benoît, Wells, Timothy N. C., Jabbar, Abdul, Gasser, Robin B.

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Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus gan Jiao, Yaqing, Preston, Sarah, Song, Hongjian, Jabbar, Abdul, Liu, Yuxiu, Baell, Jonathan, Hofmann, Andreas, Hutchinson, Dana, Wang, Tao, Koehler, Anson V., Fisher, Gillian M., Andrews, Katherine T., Laleu, Benoît, Palmer, Michael J., Burrows, Jeremy N., Wells, Timothy N. C., Wang, Qingmin, Gasser, Robin B.

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Novel Antimalarial Tetrazoles and Amides Active Against the Hemoglobin Degradation Pathway in Plasmodium falciparum gan Lawong, Aloysus, Gahalawat, Suraksha, Okombo, John, Striepen, Josefine, Yeo, Tomas, Mok, Sachel, Deni, Ioanna, Bridgford, Jessica L., Niederstrasser, Hanspeter, Zhou, Anwu, Posner, Bruce, Wittlin, Sergio, Gamo, Francisco Javier, Crespo, Benigno, Churchyard, Alisje, Baum, Jake, Mittal, Nimisha, Winzeler, Elizabeth, Laleu, Benoît, Palmer, Michael J., Charman, Susan A., Fidock, David A., Ready, Joseph M., Phillips, Margaret A.

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Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors gan Okaniwa, Masanori, Shibata, Akira, Ochida, Atsuko, Akao, Yuichiro, White, Karen L., Shackleford, David M., Duffy, Sandra, Lucantoni, Leonardo, Dey, Sumanta, Striepen, Josefine, Yeo, Tomas, Mok, Sachel, Aguiar, Anna Caroline C., Sturm, Angelika, Crespo, Benigno, Sanz, Laura M., Churchyard, Alisje, Baum, Jake, Pereira, Dhelio B., Guido, Rafael V. C., Dechering, Koen J., Wittlin, Sergio, Uhlemann, Anne-Catrin, Fidock, David A., Niles, Jacquin C., Avery, Vicky M., Charman, Susan A., Laleu, Benoît

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The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance gan Murithi, James M., Deni, Ioanna, Pasaje, Charisse Flerida A., Okombo, John, Bridgford, Jessica L., Gnädig, Nina F., Edwards, Rachel L., Yeo, Tomas, Mok, Sachel, Burkhard, Anna Y., Coburn-Flynn, Olivia, Istvan, Eva S., Sakata-Kato, Tomoyo, Gomez-Lorenzo, Maria G., Cowell, Annie N., Wicht, Kathryn J., Le Manach, Claire, Kalantarov, Gavreel F., Dey, Sumanta, Duffey, Maëlle, Laleu, Benoît, Lukens, Amanda K., Ottilie, Sabine, Vanaerschot, Manu, Trakht, Ilya N., Gamo, Francisco-Javier, Wirth, Dyann F., Goldberg, Daniel E., Odom John, Audrey R., Chibale, Kelly, Winzeler, Elizabeth A., Niles, Jacquin C., Fidock, David A.

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Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate dehydrogenase inhibitor series gan Palmer, Michael J., Deng, Xiaoyi, Watts, Shawn, Krilov, Goran, Gerasyuto, Aleksey, Kokkonda, Sreekanth, El Mazouni, Farah, White, John, White, Karen L., Striepen, Josefine, Bath, Jade, Schindler, Kyra, Yeo, Tomas, Shackleford, David M., Mok, Sachel, Deni, Ioanna, Lawong, Aloysus, Huang, Ann, Chen, Gong, Wang, Wen, Jayaseelan, Jaya, Katneni, Kasiram, Patil, Rahul, Saunders, Jessica, Shahi, Shatrughan P., Chittimalla, Rajesh, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Wittlin, Sergio, Tumwebaze, Patrick K., Rosenthal, Philip J., Cooper, Roland A., Campos Aguiar, Anna Caroline, Guido, Rafael V.C., Pereira, Dhelio B., Mittal, Nimisha, Winzeler, Elizabeth A., Tomchick, Diana R., Laleu, Benoît, Burrows, Jeremy N., Rathod, Pradipsinh K., Fidock, David A., Charman, Susan A., Phillips, Margaret A.

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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond gan Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.

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