Resultats de la cerca - Lacy M. Simons

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  1. 1
    GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors

    GS-CA1 and lenacapavir stabilize the HIV-1 core and modulate the core interaction with cellular factors per Anastasia Selyutina, Pan Hu, Sorin O. Miller, Lacy M. Simons, Hyun Jae Yu, Judd F. Hultquist, Kyeongeun Lee, Vineet N. KewalRamani, Felipe Diaz‐Griffero

    Publicat 2021
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  2. 2
    Genetically encoding multiple functionalities into extracellular vesicles for the targeted delivery of biologics to T cells

    Genetically encoding multiple functionalities into extracellular vesicles for the targeted delivery of biologics to T cells per Devin M. Stranford, Lacy M. Simons, Katherine E. Berman, Luyi Cheng, Beth N. DiBiase, Michelle Hung, Julius B. Lucks, Judd F. Hultquist, Joshua N. Leonard

    Publicat 2023
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  3. 3
    Deviations in RSV epidemiological patterns and population structures in the United States following the COVID-19 pandemic

    Deviations in RSV epidemiological patterns and population structures in the United States following the COVID-19 pandemic per Estefany Rios-Guzman, Lacy M. Simons, Taylor J. Dean, Francesca Agnes, Anna Pawlowski, Arghavan Alisoltani, Hannah Nam, Michael G. Ison, Egon A. Ozer, Ramón Lorenzo-Redondo, Judd F. Hultquist

    Publicat 2024
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  4. 4
    The impact of remdesivir on SARS-CoV-2 evolution in vivo

    The impact of remdesivir on SARS-CoV-2 evolution in vivo per Ted Ling-Hu, Lacy M. Simons, Estefany Rios-Guzman, Alexandre Machado de Sant’Anna Carvalho, Maria Francesca Reyes Agnes, Arghavan Alisoltani, Egon A. Ozer, Ramón Lorenzo-Redondo, Judd F. Hultquist

    Publicat 2025
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  5. 5
    A Unique Clade of SARS-CoV-2 Viruses is Associated with Lower Viral Loads in Patient Upper Airways

    A Unique Clade of SARS-CoV-2 Viruses is Associated with Lower Viral Loads in Patient Upper Airways per Ramón Lorenzo-Redondo, Hannah Nam, Scott C. Roberts, Lacy M. Simons, Lawrence J. Jennings, Chao Qi, Chad J. Achenbach, Alan R. Hauser, Michael G. Ison, Judd F. Hultquist, Egon A. Ozer

    Publicat 2020
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  6. 6
    A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways

    A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways per Ramón Lorenzo-Redondo, Hannah Nam, Scott C. Roberts, Lacy M. Simons, Lawrence J. Jennings, Chao Qi, Chad J. Achenbach, Alan R. Hauser, Michael G. Ison, Judd F. Hultquist, Egon A. Ozer

    Publicat 2020
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  7. 7
    Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core

    Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core per Anastasia Selyutina, Mirjana Persaud, Lacy M. Simons, Ángel Bulnes‐Ramos, Cindy Buffone, Alicia Martínez‐López, Viviana Scoca, Francesca Di Nunzio, Joseph Hiatt, Alexander Marson, Nevan J. Krogan, Judd F. Hultquist, Felipe Diaz‐Griffero

    Publicat 2020
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  8. 8
    Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes

    Plasmodium falciparum sexual differentiation in malaria patients is associated with host factors and GDV1-dependent genes per Miho Usui, Surendra K. Prajapati, Ruth Ayanful‐Torgby, Festus K. Acquah, Elizabeth Cudjoe, Courage Kakaney, Jones A. Amponsah, Evans K. Obboh, D. Reddy, Michelle C. Barbeau, Lacy M. Simons, Beata Czesny, Sorana Raiciulescu, Cara Olsen, Benjamin Abuaku, Linda Eva Amoah, Kim C. Williamson

    Publicat 2019
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  9. 9
    Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria

    Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria per Egon A. Ozer, Lacy M. Simons, Moses Olubusuyi Adewumi, Adeola Fowotade, Ewean Chukwuma Omoruyi, Johnson Adekunle Adeniji, Oluseyi A. Olayinka, Taylor J. Dean, Janet Zayas, Pavan Bhimalli, Michelle K. Ash, Almoustapha Issiaka Maïga, Anou M. Somboro, Mamoudou Maïga, Adam Godzik, Jeffrey R. Schneider, João I. Mamede, Babafemi Taiwo, Judd F. Hultquist, Ramón Lorenzo-Redondo

    Publicat 2022
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  10. 10
    Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA

    Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA per Sunnie M. Yoh, João I. Mamede, Derrick Lau, Narae Ahn, María Teresa Sánchez-Aparicio, Joshua Temple, Andrew Tuckwell, Nina V. Fuchs, Gianguido C. Cianci, Laura Riva, Heather M. Curry, Xin Yin, Stéphanie Gambut, Lacy M. Simons, Judd F. Hultquist, Renate König, Yong Xiong, Adolfo Garcı́a-Sastre, Till Böcking, Thomas J. Hope, Sumit K. Chanda

    Publicat 2022
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  11. 11
    Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19

    Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19 per Rogan A. Grant, Taylor A. Poor, Lango Sichizya, Estefani Diaz, Joseph I. Bailey, Sahil Soni, Karolina J. Senkow, Xochítl G. Pérez-Leonor, Hiam Abdala‐Valencia, Ziyan Lu, Helen K. Donnelly, Lacy M. Simons, Egon A. Ozer, Robert M. Tighe, Jon W. Lomasney, Richard G. Wunderink, Benjamin D. Singer, Alexander V. Misharin, G. R. Scott Budinger

    Publicat 2024
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  12. 12
    A functional map of HIV-host interactions in primary human T cells

    A functional map of HIV-host interactions in primary human T cells per Joseph Hiatt, Judd F. Hultquist, Michael McGregor, Mehdi Bouhaddou, Ryan T. Leenay, Lacy M. Simons, Janet M. Young, Paige Haas, Theodore L. Roth, Victoria Tobin, Jason A. Wojcechowskyj, Jonathan M. Woo, Ujjwal Rathore, Devin A. Cavero, Eric Shifrut, Thông Nguyen, Kelsey M. Haas, Harmit S. Malik, Jennifer A. Doudna, Andrew P. May, Alexander Marson, Nevan J. Krogan

    Publicat 2022
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  13. 13
    Global siRNA screen identifies human host factors critical for SARS-CoV-2 replication and late stages of infection

    Global siRNA screen identifies human host factors critical for SARS-CoV-2 replication and late stages of infection per Xin Yin, Yuan Pu, Shuofeng Yuan, Lars Pache, Christopher Churas, Stuart Weston, Laura Riva, Lacy M. Simons, William J. Cisneros, Thomas Mandel Clausen, Grace Biddle, Simon Doss-Gollin, Meagan E. Deming, Paul D. De Jesus, Ha Na Kim, Daniel Fuentes, John M. Whitelock, Jeffrey D. Esko, Megan S. Lord, Ignacio Mena, Adolfo García-Sastre, Judd F. Hultquist, Matthew B. Frieman, Trey Ideker, Dexter Pratt, Laura Martin‐Sancho, Sumit K. Chanda

    Publicat 2025
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  14. 14
    Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveal limited infectious virus shedding and restricted tissue distribution

    Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveal limited infectious virus shedding and restricted tissue distribution per Ruian Ke, Pamela P. Martinez, Rebecca L. Smith, Laura Gibson, Chad J. Achenbach, Sally M. McFall, Chao Qi, Joshua Jacob, Etienne Dembele, Camille Bundy, Lacy M. Simons, Egon A. Ozer, Judd F. Hultquist, Ramón Lorenzo-Redondo, Anita Opdycke, Claudia Hawkins, Robert L. Murphy, Agha Zeeshan Mirza, Madison Conte, Nicholas Gallagher, Chun Huai Luo, Junko Jarrett, Abigail Conte, Ruifeng Zhou, Mireille Farjo, Gloria Rendon, Christopher J. Fields, Leyi Wang, Richard Fredrickson, Melinda E. Baughman, Karen Chiu, Hannah Choi, Kevin R. Scardina, Alyssa N. Owens, John Broach, Bruce Barton, Péter Lázár, Matthew L. Robinson, Heba H. Mostafa, Yukari C. Manabe, Andrew Pekosz, David D. McManus, Christopher B. Brooke

    Publicat 2021
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  15. 15
    Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution

    Longitudinal Analysis of SARS-CoV-2 Vaccine Breakthrough Infections Reveals Limited Infectious Virus Shedding and Restricted Tissue Distribution per Ruian Ke, Pamela P. Martinez, Rebecca L. Smith, Laura Gibson, Chad J. Achenbach, Sally M. McFall, Chao Qi, Joshua Jacob, Etienne Dembele, Camille Bundy, Lacy M. Simons, Egon A. Ozer, Judd F. Hultquist, Ramón Lorenzo-Redondo, Anita Opdycke, Claudia Hawkins, Robert L. Murphy, Agha Zeeshan Mirza, Madison Conte, Nicholas Gallagher, Chun Huai Luo, Junko Jarrett, Abigail Conte, Ruifeng Zhou, Mireille Farjo, Gloria Rendon, Christopher J. Fields, Leyi Wang, Richard Fredrickson, Melinda E. Baughman, Karen Chiu, Hannah Choi, Kevin R. Scardina, Alyssa N. Owens, John Broach, Bruce Barton, Péter Lázár, Matthew L. Robinson, Heba H. Mostafa, Yukari C. Manabe, Andrew Pekosz, David D. McManus, Christopher B. Brooke

    Publicat 2022
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