Resultados de procura - Kyle W. Sloop

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  1. 1
    Physiology and Emerging Biochemistry of the Glucagon-Like Peptide-1 Receptor

    Physiology and Emerging Biochemistry of the Glucagon-Like Peptide-1 Receptor por Francis S. Willard, Kyle W. Sloop

    Publicado 2012
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  2. 2
    Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor

    Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor por Francis S. Willard, Ana B. Bueno, Kyle W. Sloop

    Publicado 2012
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  3. 3
    How May GIP Enhance the Therapeutic Efficacy of GLP-1?

    How May GIP Enhance the Therapeutic Efficacy of GLP-1? por Ricardo J. Samms, Matthew P. Coghlan, Kyle W. Sloop

    Publicado 2020
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  4. 4
    The current state of <scp>GPCR</scp>‐based drug discovery to treat metabolic disease

    The current state of <scp>GPCR</scp>‐based drug discovery to treat metabolic disease por Kyle W. Sloop, Paul J. Emmerson, Michael A. Statnick, Francis S. Willard

    Publicado 2018
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  5. 5
    Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery

    Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery por Daniel A. Briere, Ana B. Bueno, Ellen J. Gunn, M. Dodson Michael, Kyle W. Sloop

    Publicado 2017
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  6. 6
    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1b, multicentre, blinded, placebo‐controlled, randomized, multiple‐ascending‐dose study in people with type 2 diabetes

    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1b, multicentre, blinded, placebo‐controlled, randomized, multiple‐... por Edward Pratt, Xiaosu Ma, Rong Liu, Deborah Robins, Tamer Coşkun, Kyle W. Sloop, Axel Haupt, Charles T. Benson

    Publicado 2023
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  7. 7
    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1a, blinded, placebo‐controlled, randomized, single‐ and multiple‐ascending‐dose study in healthy participants

    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1a, blinded, placebo‐controlled, randomized, single‐ and multiple‐a... por Edward Pratt, Xiaosu Ma, Rong Liu, Deborah Robins, Axel Haupt, Tamer Coşkun, Kyle W. Sloop, Charles T. Benson

    Publicado 2023
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  8. 8
    Differential Activation of Pituitary Hormone Genes by Human Lhx3 Isoforms with Distinct DNA Binding Properties

    Differential Activation of Pituitary Hormone Genes by Human Lhx3 Isoforms with Distinct DNA Binding Properties por Kyle W. Sloop, Bradley C. Meier, JeAnne L. Bridwell, Gretchen E. Parker, Amy McCutchan Schiller, Simon J. Rhodes

    Publicado 1999
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  9. 9
    Absence of Glucagon and Insulin Action Reveals a Role for the GLP-1 Receptor in Endogenous Glucose Production

    Absence of Glucagon and Insulin Action Reveals a Role for the GLP-1 Receptor in Endogenous Glucose Production por Lucy S. Jun, Rohn Millican, Eric D. Hawkins, Debra L. Konkol, Aaron D. Showalter, Michael E. Christe, M. Dodson Michael, Kyle W. Sloop

    Publicado 2014
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  10. 10
    Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles

    Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles por Ana B. Bueno, Aaron D. Showalter, David B. Wainscott, Cynthia Stutsman, Aranzazu Marín, James Ficorilli, Over Cabrera, Francis S. Willard, Kyle W. Sloop

    Publicado 2016
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  11. 11
    Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP

    Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP por Lawrence J. Slieker, Kyle W. Sloop, Peggy L. Surface, Aidas Kriauciunas, Frank LaQuier, Joseph Manetta, Julie M Bue-Valleskey, Thomas W. Stephens

    Publicado 1996
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  12. 12
    β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy

    β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy por Darline Garibay, Anne K. McGavigan, Seon A Lee, James Ficorilli, Amy L. Cox, M. Dodson Michael, Kyle W. Sloop, Bethany P. Cummings

    Publicado 2016
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  13. 13
    Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism

    Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism por Christine Huppertz, Britta Fischer, Young‐Bum Kim, Ko Kotani, Antonio Vidal‐Puig, Lawrence J. Slieker, Kyle W. Sloop, Bradford B. Lowell, Barbara B. Kahn

    Publicado 2001
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  14. 14
    Regulation of the Follicle-Stimulating Hormone β Gene by the LHX3 LIM-Homeodomain Transcription Factor

    Regulation of the Follicle-Stimulating Hormone β Gene by the LHX3 LIM-Homeodomain Transcription Factor por Brooke E. West, Gretchen E. Parker, Jesse J. Savage, Parinda Kiratipranon, Katherine S. Toomey, Lisa R. Beach, Stephanie C. Colvin, Kyle W. Sloop, Simon J. Rhodes

    Publicado 2004
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  15. 15
    Insulin and Glucagon: Partners for Life

    Insulin and Glucagon: Partners for Life por Jens J. Holst, William L. Holland, Jesper Gromada, Young Lee, Roger H. Unger, Hai Yan, Kyle W. Sloop, Timothy J. Kieffer, Nicolas Damond, Pedro L. Herrera

    Publicado 2017
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  16. 16
    Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers

    Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers por Matthijs K. C. Hesselink, H. A. Keizer, Lars B. Borghouts, Gert Schaart, C.F.P. Kornips, Lawrence J. Slieker, Kyle W. Sloop, Wim H. M. Saris, Patrick Schrauwen

    Publicado 2001
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  17. 17
    GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner

    GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner por Yanqing Zhang, Keshab R. Parajuli, Genevieve E. Fava, R. C. Gupta, Weiwei Xu, Lauren U. Nguyen, Anadil F. Zakaria, Vivian Fonseca, Hongjun Wang, Franck Mauvais‐Jarvis, Kyle W. Sloop, Hongju Wu

    Publicado 2018
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  18. 18
    Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes

    Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes por Yanfang Liu, M. Dodson Michael, Shera Kash, William R. Bensch, Brett P. Monia, Susan F. Murray, Keith A. Otto, Samreen K. Syed, Sanjay Bhanot, Kyle W. Sloop, John M. Sullivan, Anne Reifel‐Miller

    Publicado 2006
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  19. 19
    Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice

    Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice por Sanjay K. Pandey, Xing Yu, Lynnetta M. Watts, M. Dodson Michael, Kyle W. Sloop, Amber R. Rivard, Thomas A. Leedom, Vara Prasad Manchem, Laura Samadzadeh, Robert A. McKay, Brett P. Monia, Sanjay Bhanot

    Publicado 2007
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  20. 20
    Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue

    Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue por Ricardo J. Samms, Guofang Zhang, Wentao He, Olga Ilkayeva, Brian A. Droz, Steven M. Bauer, Cynthia Stutsman, Valentina Pirro, Kyla Collins, Ellen C Furber, Tamer Coşkun, Kyle W. Sloop, Joseph T. Brozinick, Christopher B. Newgard

    Publicado 2022
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