Resultats de la cerca - Kyle W. Sloop

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  1. 1
    Physiology and Emerging Biochemistry of the Glucagon-Like Peptide-1 Receptor

    Physiology and Emerging Biochemistry of the Glucagon-Like Peptide-1 Receptor per Francis S. Willard, Kyle W. Sloop

    Publicat 2012
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  2. 2
    Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor

    Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor per Francis S. Willard, Ana B. Bueno, Kyle W. Sloop

    Publicat 2012
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  3. 3
    How May GIP Enhance the Therapeutic Efficacy of GLP-1?

    How May GIP Enhance the Therapeutic Efficacy of GLP-1? per Ricardo J. Samms, Matthew P. Coghlan, Kyle W. Sloop

    Publicat 2020
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  4. 4
    The current state of <scp>GPCR</scp>‐based drug discovery to treat metabolic disease

    The current state of <scp>GPCR</scp>‐based drug discovery to treat metabolic disease per Kyle W. Sloop, Paul J. Emmerson, Michael A. Statnick, Francis S. Willard

    Publicat 2018
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  5. 5
    Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery

    Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery per Daniel A. Briere, Ana B. Bueno, Ellen J. Gunn, M. Dodson Michael, Kyle W. Sloop

    Publicat 2017
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  6. 6
    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1b, multicentre, blinded, placebo‐controlled, randomized, multiple‐ascending‐dose study in people with type 2 diabetes

    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1b, multicentre, blinded, placebo‐controlled, randomized, multiple‐... per Edward Pratt, Xiaosu Ma, Rong Liu, Deborah Robins, Tamer Coşkun, Kyle W. Sloop, Axel Haupt, Charles T. Benson

    Publicat 2023
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  7. 7
    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1a, blinded, placebo‐controlled, randomized, single‐ and multiple‐ascending‐dose study in healthy participants

    Orforglipron (<scp>LY3502970</scp>), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1a, blinded, placebo‐controlled, randomized, single‐ and multiple‐a... per Edward Pratt, Xiaosu Ma, Rong Liu, Deborah Robins, Axel Haupt, Tamer Coşkun, Kyle W. Sloop, Charles T. Benson

    Publicat 2023
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  8. 8
    Differential Activation of Pituitary Hormone Genes by Human Lhx3 Isoforms with Distinct DNA Binding Properties

    Differential Activation of Pituitary Hormone Genes by Human Lhx3 Isoforms with Distinct DNA Binding Properties per Kyle W. Sloop, Bradley C. Meier, JeAnne L. Bridwell, Gretchen E. Parker, Amy McCutchan Schiller, Simon J. Rhodes

    Publicat 1999
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  9. 9
    Absence of Glucagon and Insulin Action Reveals a Role for the GLP-1 Receptor in Endogenous Glucose Production

    Absence of Glucagon and Insulin Action Reveals a Role for the GLP-1 Receptor in Endogenous Glucose Production per Lucy S. Jun, Rohn Millican, Eric D. Hawkins, Debra L. Konkol, Aaron D. Showalter, Michael E. Christe, M. Dodson Michael, Kyle W. Sloop

    Publicat 2014
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  10. 10
    Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles

    Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles per Ana B. Bueno, Aaron D. Showalter, David B. Wainscott, Cynthia Stutsman, Aranzazu Marín, James Ficorilli, Over Cabrera, Francis S. Willard, Kyle W. Sloop

    Publicat 2016
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  11. 11
    Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP

    Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP per Lawrence J. Slieker, Kyle W. Sloop, Peggy L. Surface, Aidas Kriauciunas, Frank LaQuier, Joseph Manetta, Julie M Bue-Valleskey, Thomas W. Stephens

    Publicat 1996
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  12. 12
    β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy

    β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy per Darline Garibay, Anne K. McGavigan, Seon A Lee, James Ficorilli, Amy L. Cox, M. Dodson Michael, Kyle W. Sloop, Bethany P. Cummings

    Publicat 2016
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  13. 13
    Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism

    Uncoupling Protein 3 (UCP3) Stimulates Glucose Uptake in Muscle Cells through a Phosphoinositide 3-Kinase-dependent Mechanism per Christine Huppertz, Britta Fischer, Young‐Bum Kim, Ko Kotani, Antonio Vidal‐Puig, Lawrence J. Slieker, Kyle W. Sloop, Bradford B. Lowell, Barbara B. Kahn

    Publicat 2001
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  14. 14
    Regulation of the Follicle-Stimulating Hormone β Gene by the LHX3 LIM-Homeodomain Transcription Factor

    Regulation of the Follicle-Stimulating Hormone β Gene by the LHX3 LIM-Homeodomain Transcription Factor per Brooke E. West, Gretchen E. Parker, Jesse J. Savage, Parinda Kiratipranon, Katherine S. Toomey, Lisa R. Beach, Stephanie C. Colvin, Kyle W. Sloop, Simon J. Rhodes

    Publicat 2004
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  15. 15
    Insulin and Glucagon: Partners for Life

    Insulin and Glucagon: Partners for Life per Jens J. Holst, William L. Holland, Jesper Gromada, Young Lee, Roger H. Unger, Hai Yan, Kyle W. Sloop, Timothy J. Kieffer, Nicolas Damond, Pedro L. Herrera

    Publicat 2017
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  16. 16
    Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers

    Protein expression of UCP3 differs between human type 1, type 2a, and type 2b fibers per Matthijs K. C. Hesselink, H. A. Keizer, Lars B. Borghouts, Gert Schaart, C.F.P. Kornips, Lawrence J. Slieker, Kyle W. Sloop, Wim H. M. Saris, Patrick Schrauwen

    Publicat 2001
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  17. 17
    GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner

    GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner per Yanqing Zhang, Keshab R. Parajuli, Genevieve E. Fava, R. C. Gupta, Weiwei Xu, Lauren U. Nguyen, Anadil F. Zakaria, Vivian Fonseca, Hongjun Wang, Franck Mauvais‐Jarvis, Kyle W. Sloop, Hongju Wu

    Publicat 2018
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  18. 18
    Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes

    Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes per Yanfang Liu, M. Dodson Michael, Shera Kash, William R. Bensch, Brett P. Monia, Susan F. Murray, Keith A. Otto, Samreen K. Syed, Sanjay Bhanot, Kyle W. Sloop, John M. Sullivan, Anne Reifel‐Miller

    Publicat 2006
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  19. 19
    Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice

    Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice per Sanjay K. Pandey, Xing Yu, Lynnetta M. Watts, M. Dodson Michael, Kyle W. Sloop, Amber R. Rivard, Thomas A. Leedom, Vara Prasad Manchem, Laura Samadzadeh, Robert A. McKay, Brett P. Monia, Sanjay Bhanot

    Publicat 2007
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  20. 20
    Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue

    Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue per Ricardo J. Samms, Guofang Zhang, Wentao He, Olga Ilkayeva, Brian A. Droz, Steven M. Bauer, Cynthia Stutsman, Valentina Pirro, Kyla Collins, Ellen C Furber, Tamer Coşkun, Kyle W. Sloop, Joseph T. Brozinick, Christopher B. Newgard

    Publicat 2022
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