Resultats de la cerca - Kristopher A. Sarosiek

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  1. 1
    BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies

    BH3 Profiling: A Functional Assay to Measure Apoptotic Priming and Dependencies per Cameron Fraser, Jeremy Ryan, Kristopher A. Sarosiek

    Publicat 2018
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  2. 2
    Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

    Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins per Rumani Singh, Anthony Letai, Kristopher A. Sarosiek

    Publicat 2019
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  3. 3
    Inflammation and mitophagy are mitochondrial checkpoints to aging

    Inflammation and mitophagy are mitochondrial checkpoints to aging per Emma Guilbaud, Kristopher A. Sarosiek, Lorenzo Galluzzi

    Publicat 2024
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  4. 4
    Mitochondria: gatekeepers of response to chemotherapy

    Mitochondria: gatekeepers of response to chemotherapy per Kristopher A. Sarosiek, Triona Ní Chonghaile, Anthony Letai

    Publicat 2013
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  5. 5
    Radiation-Induced Cardiovascular Toxicity: Mechanisms, Prevention, and Treatment

    Radiation-Induced Cardiovascular Toxicity: Mechanisms, Prevention, and Treatment per Johan Spetz, Javid J. Moslehi, Kristopher A. Sarosiek

    Publicat 2018
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  6. 6
    T Cells and Regulated Cell Death

    T Cells and Regulated Cell Death per Johan Spetz, Adam G. Presser, Kristopher A. Sarosiek

    Publicat 2018
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  7. 7
    Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas

    Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas per Kristopher A. Sarosiek, Raquel Malumbres, Hovav Nechushtan, Andrew J. Gentles, Eli Avisar, Izidore S. Lossos

    Publicat 2009
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  8. 8
    RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis

    RAS signaling promotes resistance to JAK inhibitors by suppressing BAD-mediated apoptosis per Peter Winter, Kristopher A. Sarosiek, Kevin Lin, Manja Meggendorfer, Susanne Schnittger, Anthony Letai, Kris C. Wood

    Publicat 2014
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  9. 9
    PTP1B is a negative regulator of interleukin 4–induced STAT6 signaling

    PTP1B is a negative regulator of interleukin 4–induced STAT6 signaling per Xiaoqing Lu, Raquel Malumbres, Benjamin Shields, Xiaoyu Jiang, Kristopher A. Sarosiek, Yasodha Natkunam, Tony Tiganis, Izidore S. Lossos

    Publicat 2008
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  10. 10
    T-Cell Protein Tyrosine Phosphatase, Distinctively Expressed in Activated-B-Cell-Like Diffuse Large B-Cell Lymphomas, Is the Nuclear Phosphatase of STAT6

    T-Cell Protein Tyrosine Phosphatase, Distinctively Expressed in Activated-B-Cell-Like Diffuse Large B-Cell Lymphomas, Is the Nuclear Phosphatase of STAT6 per Xiaoqing Lu, Jun Chen, R. Tedjo Sasmono, Eric D. Hsi, Kristopher A. Sarosiek, Tony Tiganis, Izidore S. Lossos

    Publicat 2007
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  11. 11
    Differentiation stage–specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas

    Differentiation stage–specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas per Raquel Malumbres, Kristopher A. Sarosiek, Elena Cubedo, Jose W. Ruiz, Xiaoyu Jiang, Randy D. Gascoyne, Robert Tibshirani, Izidore S. Lossos

    Publicat 2008
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  12. 12
    Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage

    Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage per Paula Gutierrez‐Martinez, Leah J. Hogdal, Manavi Nagai, Miriama Krutá, Rumani Singh, Kristopher A. Sarosiek, André Nussenzweig, Isabel Beerman, Anthony Letai, Derrick J. Rossi

    Publicat 2018
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  13. 13
    HSF1 phase transition mediates stress adaptation and cell fate decisions

    HSF1 phase transition mediates stress adaptation and cell fate decisions per Giorgio Gaglia, Rumana Rashid, Clarence Yapp, Gaurav N. Joshi, Carmen G Li, Susan Lindquist, Kristopher A. Sarosiek, Luke Whitesell, Peter K. Sorger, Sandro Santagata

    Publicat 2020
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  14. 14
    BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response

    BID Preferentially Activates BAK while BIM Preferentially Activates BAX, Affecting Chemotherapy Response per Kristopher A. Sarosiek, Xiaoke Chi, John A. Bachman, Joshua J. Sims, Joan Montero, Luv Patel, Annabelle Flanagan, David W. Andrews, Peter K. Sorger, Anthony Letai

    Publicat 2013
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  15. 15
    Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma

    Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma per Kristopher A. Sarosiek, Lucas E. Cavallin, Shruti Bhatt, Ngoc L. Toomey, Yasodha Natkunam, Wilfredo Blasini, Andrew J. Gentles, Juan Carlos Ramos, Enrique A. Mesri, Izidore S. Lossos

    Publicat 2010
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  16. 16
    Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance

    Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance per Jessie Pécot, Laurent Maillet, Janic Le Pen, Céline Vuillier, Sophie de Carné Trécesson, Aurélie Fétiveau, Kristopher A. Sarosiek, Florian J. Bock, Frédérique Braun, Anthony Letai, Stephen W. G. Tait, Fabien Gautier, Philippe Juin

    Publicat 2016
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  17. 17
    Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers

    Failure to Induce Apoptosis via BCL-2 Family Proteins Underlies Lack of Efficacy of Combined MEK and PI3K Inhibitors for KRAS-Mutant Lung Cancers per Aaron N. Hata, Alan T. Yeo, Anthony C. Faber, Eugene Lifshits, Zhao Chen, Katherine A. Cheng, Zandra E. Walton, Kristopher A. Sarosiek, Anthony Letai, Rebecca S. Heist, Mari Mino‐Kenudson, Kwok‐Kin Wong, Jeffrey A. Engelman

    Publicat 2014
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  18. 18
    BCL-XL directly modulates RAS signalling to favour cancer cell stemness

    BCL-XL directly modulates RAS signalling to favour cancer cell stemness per Sophie de Carné Trécesson, Frédérique Souazé, Agnès Basseville, Anne-Charlotte Bernard, Jessie Pécot, Jonathan Lopez, Margaux Bessou, Kristopher A. Sarosiek, Anthony Letai, Sophie Barillé‐Nion, Isabelle Valo, Olivier Coqueret, Catherine Guette, Mario Campone, Fabien Gautier, Philippe Juin

    Publicat 2017
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  19. 19
    Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics

    Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics per Veerle W. Daniëls, Jason J. Zoeller, Nick van Gastel, Kelley E. McQueeney, Salma Parvin, Danielle S. Potter, Geoffrey Fell, Vinícius Guimarães Ferreira, Binyam Yilma, Rajat Gupta, Johan Spetz, Patrick Bhola, Jennifer E. Endress, Isaac S. Harris, Emanuel Carrilho, Kristopher A. Sarosiek, David T. Scadden, Joan S. Brugge, Anthony Letai

    Publicat 2021
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  20. 20
    Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance

    Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance per Neil Johnson, Shawn F. Johnson, Wei Yao, Yu-Chen Li, Young-Eun Choi, Andrea J. Bernhardy, Yifan Wang, Marzia Capelletti, Kristopher A. Sarosiek, Lisa A. Moreau, Dipanjan Chowdhury, Anneka Wickramanayake, Maria I. Harrell, Joyce F. Liu, Alan D. D’Andrea, Alexander Miron, Elizabeth M. Swisher, Geoffrey I. Shapiro

    Publicat 2013
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