Výsledky vyhledávání - Kristin Tsuo

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  1. 1
    Challenges and Opportunities for Developing More Generalizable Polygenic Risk Scores

    Challenges and Opportunities for Developing More Generalizable Polygenic Risk Scores Autor Ying Wang, Kristin Tsuo, Masahiro Kanai, Benjamin M. Neale, Alicia R. Martin

    Vydáno 2022
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  2. 2
    A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans

    A Neanderthal Sodium Channel Increases Pain Sensitivity in Present-Day Humans Autor Hugo Zeberg, Michael Dannemann, Kristoffer Sahlholm, Kristin Tsuo, Tomislav Maričić, Victor Wiebe, Wulf Hevers, Hugh P. C. Robinson, Janet Kelso, Svante Pääbo

    Vydáno 2020
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  3. 3
    Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology

    Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology Autor Ying Wang, Masahiro Kanai, Taotao Tan, Mireille Kamariza, Kristin Tsuo, Kai Yuan, Wei Zhou, Yukinori Okada, Hailiang Huang, Patrick Turley, Elizabeth G. Atkinson, Alicia R. Martin

    Vydáno 2023
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  4. 4
    Low and differential polygenic score generalizability among African populations due largely to genetic diversity

    Low and differential polygenic score generalizability among African populations due largely to genetic diversity Autor Lerato Majara, Allan Kalungi, Nastassja Koen, Kristin Tsuo, Ying Wang, Rahul Gupta, Lethukuthula L. Nkambule, Heather J. Zar, Dan J. Stein, Eugene Kinyanda, Elizabeth G. Atkinson, Alicia R. Martin

    Vydáno 2023
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  5. 5
    Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity

    Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity Autor Kristin Tsuo, Wei Zhou, Ying Wang, Masahiro Kanai, Shinichi Namba, Rahul Gupta, Lerato Majara, Lethukuthula L. Nkambule, Takayuki Morisaki, Yukinori Okada, Benjamin M. Neale, Mark J. Daly, Alicia R. Martin

    Vydáno 2022
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  6. 6
    Nuclear genetic control of mtDNA copy number and heteroplasmy in humans

    Nuclear genetic control of mtDNA copy number and heteroplasmy in humans Autor Rahul Gupta, Masahiro Kanai, Timothy Durham, Kristin Tsuo, Jason G. McCoy, Anna V. Kotrys, Wei Zhou, Patrick F. Chinnery, Konrad J. Karczewski, Sarah E. Calvo, Benjamin M. Neale, Vamsi K. Mootha

    Vydáno 2023
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  7. 7
    Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects

    Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects Autor Konrad J. Karczewski, Rahul Gupta, Masahiro Kanai, Wenhan Lu, Kristin Tsuo, Ying Wang, Raymond K. Walters, Patrick Turley, Shawneequa Callier, Nirav N. Shah, Nikolas Baya, Duncan S. Palmer, Jacqueline I. Goldstein, Gopal Sarma, Matthew Solomonson, Nathan Cheng, Sam Bryant, Claire Churchhouse, Caroline Cusick, Timothy Poterba, John Compitello, Daniel A. King, Wei Zhou, Cotton Seed, Hilary K. Finucane, Mark J. Daly, Benjamin M. Neale, Elizabeth G. Atkinson, Alicia R. Martin

    Vydáno 2024
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  8. 8
    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

    Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts Autor Ying Wang, Shinichi Namba, Esteban A. Lopera-Maya, Sini Kerminen, Kristin Tsuo, Kristi Läll, Masahiro Kanai, Wei Zhou, Kuan-Han Wu, Marie-Julie Favé, Laxmi Bhatta, Philip Awadalla, Ben Brumpton, Patrick Deelen, Kristian Hveem, Valeria Lo Faro, Reedik Mägi, Yoshinori Murakami, Serena Sanna, Jordan W. Smoller, Jasmina Uzunović, Brooke N. Wolford, Cristen J. Willer, Eric R. Gamazon, Nancy J. Cox, Ida Surakka, Yukinori Okada, Alicia R. Martin, Jibril Hirbo, Wei Zhou, Masahiro Kanai, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo, Jibril Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brooke N. Wolford, Valeria Lo Faro, Esteban A. Lopera-Maya, Kristi Läll, Marie-Julie Favé, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Mutaamba Maasha, Juulia Partanen, Ben Brumpton, Sameer Chavan, Tzu‐Ting Chen, Michelle Daya, Yi Ding, Yen‐Chen Anne Feng, Christopher R. Gignoux, Sarah E. Graham, Whitney Hornsby, Nathan Ingold, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Priit Palta, Anita Pandit, Michael Preuß, Unnur Þorsteinsdóttir, Jasmina Uzunović, Matthew Zawistowski, Xue Zhong, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Chris Griffiths, Yu Guo, Karen A. Hunt, Takahiro Konuma, Riccardo E. Marioni, Jansonius Nomdo, Snehal Patil, Nicholas Rafaels, Anne Richmond, Jonathan Shortt, Péter Straub, Ran Tao, Brett Vanderwerff, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia‐Yen Chen, Judy H. Cho, George Davey Smith, Hilary K. Finucane, Lude Franke, Eric R. Gamazon

    Vydáno 2023
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  9. 9
    The immune factors driving DNA methylation variation in human blood

    The immune factors driving DNA methylation variation in human blood Autor Jacob Bergstedt, Sadoune Ait Kaci Azzou, Kristin Tsuo, Anthony Jaquaniello, Alejandra Urrutia, Maxime Rotival, David Lin, Julia L. MacIsaac, Michael S. Kobor, Matthew L. Albert, Darragh Duffy, Étienne Patin, Lluı́s Quintana-Murci, Laurent Abel, Andrés Alcover, Hugues Aschard, Philippe Bousso, Nollaig M. Bourke, Petter Brodin, Pierre Bruhns, Nadine Cerf‐Bensussan, Ana Cumano, Christophe d’Enfert, Ludovic Deriano, Marie‐Agnès Dillies, James P. Di Santo, Françoise Dromer, Gérard Eberl, Jost Enninga, Jacques Fellay, Ivo G. Boneca, Milena Hasan, Gunilla Karlsson Hedestam, Serge Herçberg, Molly A. Ingersoll, Olivier Lantz, Rose Anne Kenny, Mickaël Ménager, Frédérique Michel, Hugo Mouquet, Cliona O’Farrelly, Sandra Pellegrini, Antonio Rausell, Frédéric Rieux‐Laucat, Lars Rogge, Magnus Fontes, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Frédéric Tangy, Antoine Toubert, Mathilde Touvier, Marie‐Noëlle Ungeheuer, Christophe Zimmer, Lluı́s Quintana-Murci

    Vydáno 2022
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  10. 10
    The role of polygenic risk and susceptibility genes in breast cancer over the course of life

    The role of polygenic risk and susceptibility genes in breast cancer over the course of life Autor Nina Mars, Elisabeth Widén, Sini Kerminen, Tuomo J Meretoja, Matti Pirinen, Pietro Della Briotta Parolo, Priit Palta, Aki Havulinna, Amanda Elliott, Anastasia Shcherban, Andrea Ganna, Anu Jalanko, Arto Lehisto, Elina Kilpeläinen, Georg Brein, Awaisa Ghazal, Hannele Laivuori, Henrike Heyne, Jarmo Harju, Jiwoo Lee, Juha Karjalainen, Jukka Koskela, Kalle Pärn, Kati Donner, Kristin Tsuo, Manuel González Jiménez, Mari Kaunisto, Mari Niemi, Mary Pat Reeve, Mervi Aavikko, Mitja Kurki, Oluwaseun Alexander Dada, Pietro Della Briotta Parolo, Risto Kajanne, Sina Rüeger, Susanna Lemmelä, Taru Tukiainen, Jaakko Tuomilehto, Timo P. Sipilä, Tuomo Kiiskinen, Vincent Llorens, Adam Ziemann, Anne Lehtonen, Apinya Lertratanakul, Bob Georgantas, Bridget Riley‐Gillis, Danjuma Quarless, Fedik Rahimov, Howard Jacob, Jeffrey F. Waring, J. Wade Davis, Nizar Smaoui, Relja Popovic, Sahar Esmaeeli, Athena Matakidou, Ben Challis, David A. Close, Eleonor Wigmore, Slavé Petrovski, Chia‐Yen Chen, Ellen Tsai, Heiko Runz, Jimmy Z. Liu, Paola G. Bronson, Sally John, Sanni Lahdenperä, Stephanie Loomis, Susan Eaton, Yunfeng Huang, Erika Kvikstad, Minal Çalışkan, Samir Wadhawan, Elmutaz Shaikho Elhaj Mohammed, Janet van Adelsberg, Joseph Maranville, Marla Hochfeld, Robert Plenge, Shameek Biswas, Steven M. Greenberg, Andrew S. Peterson, David F. Choy, Diana Chang, Edmond Teng, Erich C. Strauss, Geoff Kerchner, Hao Chen, Hubert Chen, Jennifer L. Schutzman, John A. Michon, Julie Hunkapiller, Mark I. McCarthy, Natalie Bowers, Sarah A. Pendergrass, Tushar Bhangale, David Pulford, Dawn Waterworth, Diptee Kulkarni, Fanli Xu, Jo Betts, Jorge Esparza Gordillo

    Vydáno 2020
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  11. 11
    Global Biobank Meta-analysis Initiative: powering genetic discovery across human diseases

    Global Biobank Meta-analysis Initiative: powering genetic discovery across human diseases Autor Wei Zhou, Masahiro Kanai, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo, Jibril Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brooke N. Wolford, Valeria Lo Faro, Esteban A. Lopera-Maya, Kristi Läll, Marie-Julie Favé, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Mutaamba Maasha, Ben Brumpton, Sameer Chavan, Tzu‐Ting Chen, Michelle Daya, Yi Ding, Yen‐Chen Anne Feng, Christopher R. Gignoux, Sarah E. Graham, Whitney Hornsby, Nathan Ingold, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Priit Palta, Anita Pandit, Michael Preuß, Unnur Þorsteinsdóttir, Jasmina Uzunović, Matthew Zawistowski, Xue Zhong, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Chris Griffiths, Yu Guo, Karen A. Hunt, Takahiro Konuma, Riccardo E. Marioni, Jansonius Nomdo, Snehal Patil, Nicholas Rafaels, Anne Richmond, Jonathan Shortt, Péter Straub, Ran Tao, Brett Vanderwerff, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia‐Yen Chen, Judy H. Cho, George Davey Smith, Hilary K. Finucane, Lude Franke, Eric R. Gamazon, Andrea Ganna, Tom R. Gaunt, Tian Ge, Hailiang Huang, Jennifer E. Huffman, Clara Lajonchere, Matthew H. Law, Liming Li, Cecilia M. Lindgren, Ruth J. F. Loos, Stuart MacGregor, Koichi Matsuda, Catherine M. Olsen, David J. Porteous, Jordan A. Shavit, Harold Snieder, Richard C. Trembath, Judith M. Vonk, David C. Whiteman, Stephen J. Wicks, Cisca Wijmenga, John Wright, Jie Zheng, Xiang Zhou, Philip Awadalla, Michael Boehnke, Nancy J. Cox, Daniel H. Geschwind, Caroline Hayward, Kristian Hveem

    Vydáno 2021
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  12. 12
    Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease

    Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease Autor Wei Zhou, Masahiro Kanai, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo, Jibril Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brooke N. Wolford, Valeria Lo Faro, Esteban A. Lopera-Maya, Kristi Läll, Marie-Julie Favé, Juulia Partanen, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Mutaamba Maasha, Ben Brumpton, Sameer Chavan, Tzu‐Ting Chen, Michelle Daya, Yi Ding, Yen‐Chen Anne Feng, Lindsay Guare, Christopher R. Gignoux, Sarah E. Graham, Whitney Hornsby, Nathan Ingold, Said I. Ismail, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Sonia Moreno‐Grau, Kisung Nam, Priit Palta, Anita Pandit, Michael Preuß, Chadi Saad, Shefali Setia-Verma, Unnur Þorsteinsdóttir, Jasmina Uzunović, Anurag Verma, Matthew Zawistowski, Xue Zhong, Nahla Afifi, Kawthar Al-Dabhani, Asma Al Thani, Yuki Bradford, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Scott M. Damrauer, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Eleni Fthenou, Gilberto Gonzalez-Arroyo, Chris Griffiths, Yu Guo, Karen A. Hunt, Alexander Ioannidis, Nomdo M. Jansonius, Takahiro Konuma, Ming Ta Michael Lee, Arturo Lopez-Pineda, Yuta Matsuda, Riccardo E. Marioni, Babak Moatamed, Marco A. Nava-Aguilar, Kensuke Numakura, Snehal Patil, Nicholas Rafaels, Anne Richmond, Agustin Rojas‐Muñoz, Jonathan Shortt, Péter Straub, Ran Tao, Brett Vanderwerff, Manvi Vernekar, Yogasudha Veturi, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia‐Yen Chen, Judy H. Cho, George Davey Smith, Hilary K. Finucane, Lude Franke, Eric R. Gamazon, Andrea Ganna, Tom R. Gaunt, Tian Ge, Hailiang Huang, Jennifer E. Huffman

    Vydáno 2022
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  13. 13
    Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

    Meta-analysis fine-mapping is often miscalibrated at single-variant resolution Autor Masahiro Kanai, Roy Elzur, Wei Zhou, Mark J. Daly, Hilary K. Finucane, Wei Zhou, Masahiro Kanai, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo, Jibril Hirbo, Ying Wang, Arjun Bhattacharya, Huiling Zhao, Shinichi Namba, Ida Surakka, Brooke N. Wolford, Valeria Lo Faro, Esteban A. Lopera-Maya, Kristi Läll, Marie-Julie Favé, Juulia Partanen, Sinéad B. Chapman, Juha Karjalainen, Mitja Kurki, Mutaamba Maasha, Ben Brumpton, Sameer Chavan, Tzu‐Ting Chen, Michelle Daya, Yi Ding, Yen‐Chen Anne Feng, Lindsay Guare, Christopher R. Gignoux, Sarah E. Graham, Whitney Hornsby, Nathan Ingold, Said I. Ismail, Ruth Johnson, Triin Laisk, Kuang Lin, Jun Lv, Iona Y. Millwood, Sonia Moreno‐Grau, Kisung Nam, Priit Palta, Anita Pandit, Michael Preuß, Chadi Saad, Shefali Setia-Verma, Unnur Þorsteinsdóttir, Jasmina Uzunović, Anurag Verma, Matthew Zawistowski, Xue Zhong, Nahla Afifi, Kawthar Al-Dabhani, Asma Al Thani, Yuki Bradford, Archie Campbell, Kristy Crooks, Geertruida H. de Bock, Scott M. Damrauer, Nicholas J. Douville, Sarah Finer, Lars G. Fritsche, Eleni Fthenou, Gilberto Gonzalez-Arroyo, Chris Griffiths, Yu Guo, Karen A. Hunt, Alexander Ioannidis, Nomdo M. Jansonius, Takahiro Konuma, Ming Ta Michael Lee, Arturo Lopez-Pineda, Yuta Matsuda, Riccardo E. Marioni, Babak Moatamed, Marco A. Nava-Aguilar, Kensuke Numakura, Snehal Patil, Nicholas Rafaels, Anne Richmond, Agustin Rojas‐Muñoz, Jonathan Shortt, Péter Straub, Ran Tao, Brett Vanderwerff, Manvi Vernekar, Yogasudha Veturi, Kathleen C. Barnes, Marike Boezen, Zhengming Chen, Chia‐Yen Chen, Judy H. Cho, George Davey Smith, Hilary K. Finucane, Lude Franke, Eric R. Gamazon

    Vydáno 2022
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