Search Results - Kristin Brown

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  1. 1
    The phosphoinositide 3-kinase pathway and therapy resistance in cancer

    The phosphoinositide 3-kinase pathway and therapy resistance in cancer by Kristin Brown, Alex Toker

    Published 2015
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  2. 2
    MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy

    MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy by Kristin Brown, Laleh Montaser‐Kouhsari, Andrew H. Beck, Alex Toker

    Published 2015
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  3. 3
    Adaptive Reprogramming of <i>De Novo</i> Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer

    Adaptive Reprogramming of <i>De Novo</i> Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer by Kristin Brown, Jessica B. Spinelli, John M. Asara, Alex Toker

    Published 2017
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  4. 4
    PKD Controls αvβ3 Integrin Recycling and Tumor Cell Invasive Migration through Its Substrate Rabaptin-5

    PKD Controls αvβ3 Integrin Recycling and Tumor Cell Invasive Migration through Its Substrate Rabaptin-5 by Claudine Christoforides, Elena Rainero, Kristin Brown, Jim C. Norman, Alex Toker

    Published 2012
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  5. 5
    Characterization of mitochondrial haplogroups in a large population-based sample from the United States

    Characterization of mitochondrial haplogroups in a large population-based sample from the United States by Sabrina L. Mitchell, Robert Goodloe, Kristin Brown‐Gentry, Sarah A. Pendergrass, Deborah G. Murdock, Dana C. Crawford

    Published 2014
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  6. 6
    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth

    YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth by Srimayee Vaidyanathan, Talhah M. Salmi, Rasan M Sathiqu, Malcolm J. McConville, Andrew G. Cox, Kristin Brown

    Published 2022
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  7. 7
    The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis

    The KEAP1–NRF2 pathway regulates TFEB/TFE3-dependent lysosomal biogenesis by Athena Jessica S. Ong, Cerys E. Bladen, Tara A. Tigani, Anthony P. Karamalakis, Kimberley Evason, Kristin Brown, Andrew G. Cox

    Published 2023
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  8. 8
    Direct Modification of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor by Dietary Isothiocyanates

    Direct Modification of the Proinflammatory Cytokine Macrophage Migration Inhibitory Factor by Dietary Isothiocyanates by Kristin Brown, Frances H. Blaikie, Robin A.J. Smith, Joel D. A. Tyndall, Hongqi Lue, Jürgen Bernhagen, Christine C. Winterbourn, Mark B. Hampton

    Published 2009
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  9. 9
    PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations

    PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations by Joshua C. Denny, Marylyn D. Ritchie, Melissa Basford, Jill M. Pulley, Lisa Bastarache, Kristin Brown‐Gentry, Deede Wang, Dan Masys, Dan M. Roden, Dana C. Crawford

    Published 2010
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  10. 10
    Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records

    Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records by Logan Dumitrescu, Marylyn D. Ritchie, Kristin Brown‐Gentry, Jill M. Pulley, Melissa Basford, Joshua C. Denny, Jorge R. Oksenberg, Dan M. Roden, Jonathan L. Haines, Dana C. Crawford

    Published 2010
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  11. 11
    Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

    Glutamine addiction promotes glucose oxidation in triple-negative breast cancer by Lake‐Ee Quek, Michelle van Geldermalsen, Yi Fang Guan, Kanu Wahi, Chelsea Mayoh, Seher Balaban, Angel Pang, Qian Wang, Mark J. Cowley, Kristin Brown, Nigel Turner, Andrew J. Hoy, Jeff Holst

    Published 2022
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  12. 12
    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway

    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway by Vicky W. T. Tan, Talhah M. Salmi, Anthony P. Karamalakis, Andrea Gillespie, Athena Jessica S. Ong, Jesse J. Balic, Yih-Chih Chan, Cerys E. Bladen, Kristin Brown, Mark A. Dawson, Andrew G. Cox

    Published 2024
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  13. 13
    Robust Replication of Genotype-Phenotype Associations across Multiple Diseases in an Electronic Medical Record

    Robust Replication of Genotype-Phenotype Associations across Multiple Diseases in an Electronic Medical Record by Marylyn D. Ritchie, Joshua C. Denny, Dana C. Crawford, Andrea H. Ramirez, Justin Weiner, Jill M. Pulley, Melissa Basford, Kristin Brown‐Gentry, Jeffrey R. Balser, Daniel R. Masys, Jonathan L. Haines, Dan M. Roden

    Published 2010
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  14. 14
    Effectiveness of Adolescent and Adult Tetanus, Reduced‐Dose Diphtheria, and Acellular Pertussis Vaccine against Pertussis

    Effectiveness of Adolescent and Adult Tetanus, Reduced‐Dose Diphtheria, and Acellular Pertussis Vaccine against Pertussis by Stanley C. Wei, Kathleen M. Tatti, Kimberly Cushing, Jennifer B. Rosen, Kristin Brown, Pamela K. Cassiday, Thomas A. Clark, Richard N. Olans, Lucia C. Pawloski, Monte D. Martin, M. Lucia Tondella, Stacey W. Martin

    Published 2010
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  15. 15
    S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury

    S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury by Andrew G. Cox, Diane C. Saunders, Peter B. Kelsey, Allie A. Conway, Yevgenia Tesmenitsky, Júlio Flávio Meirelles Marchini, Kristin Brown, Jonathan S. Stamler, Dorothy B. Colagiovanni, Gary J. Rosenthal, Kevin Croce, Trista E. North, Wolfram Goessling

    Published 2014
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  16. 16
    Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD–Driven Acute Myeloid Leukemia

    Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD–Driven Acute Myeloid Leukemia by Stefan Bjelosevic, Emily Gruber, Andrea Newbold, Carolyn Shembrey, Jennifer R. Devlin, Simon J. Hogg, Lev M. Kats, Izabela Todorovski, Zheng Fan, Thomas C. Abrehart, Giovanna Pomilio, Andrew H. Wei, Gareth P. Gregory, Stephin J. Vervoort, Kristin Brown, Ricky W. Johnstone

    Published 2021
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  17. 17
    Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study

    Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) St... by Molly A. Hall, Anurag Verma, Kristin Brown‐Gentry, Robert Goodloe, J.R. Boston, Sarah Wilson, Bob McClellan, Cara Sutcliffe, Holly H. Dilks, Nila B. Gillani, Hailing Jin, Ping Mayo, Melissa Allen, Nathalie Schnetz‐Boutaud, Dana C. Crawford, Marylyn D. Ritchie, Sarah A. Pendergrass

    Published 2014
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  18. 18
    Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium

    Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium by Timothy J. Hohman, William S. Bush, Lan Jiang, Kristin Brown‐Gentry, Eric S. Torstenson, Scott Dudek, Shubhabrata Mukherjee, Adam C. Naj, Brian W. Kunkle, Marylyn D. Ritchie, Eden R. Martin, Gerard D. Schellenberg, Richard Mayeux, Lindsay A. Farrer, Margaret A. Pericak‐Vance, Jonathan L. Haines, Tricia A. Thornton‐Wells

    Published 2015
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  19. 19
    Tumor immune evasion arises through loss of TNF sensitivity

    Tumor immune evasion arises through loss of TNF sensitivity by Conor J. Kearney, Stephin J. Vervoort, Simon J. Hogg, Kelly M. Ramsbottom, Andrew J. Freeman, Najoua Lalaoui, Lizzy Pijpers, Jessica Michie, Kristin Brown, Deborah A. Knight, Vivien R. Sutton, Paul A. Beavis, Ilia Voskoboinik, Phillip K. Darcy, John Silke, Joseph A. Trapani, Ricky W. Johnstone, Jane Oliaro

    Published 2018
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  20. 20
    Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis

    Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis by Andrew G. Cox, Allison Tsomides, Andrew J. Kim, Diane C. Saunders, Katie L. Hwang, Kimberley Evason, Jerry R. Heidel, Kristin Brown, Min Yuan, Evan C. Lien, Byung Cheon Lee, Sahar Nissim, Bryan C. Dickinson, Sagar Chhangawala, Christopher J. Chang, John M. Asara, Yariv Houvras, Vadim N. Gladyshev, Wolfram Goessling

    Published 2016
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