Suchergebnisse - Kristian W. Pajtler

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  1. 1
    Molecular mechanisms and therapeutic targets in pediatric brain tumors

    Molecular mechanisms and therapeutic targets in pediatric brain tumors von Kun-Wei Liu, Kristian W. Pajtler, Barbara C. Worst, Stefan M. Pfister, Robert J. Wechsler‐Reya

    Veröffentlicht 2017
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  2. 2
    Evaluation of Storage Tubes for Combined Analysis of Circulating Nucleic Acids in Liquid Biopsies

    Evaluation of Storage Tubes for Combined Analysis of Circulating Nucleic Acids in Liquid Biopsies von Aoife Ward, Judith Lenhardt, Tania Witte, Denise Keitel, Anna Kaufhold, Kendra K. Maaß, Kristian W. Pajtler, Christof Sohn, Sarah Schott

    Veröffentlicht 2019
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  3. 3
    EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma

    EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma von Jens-Martin Hübner, Torsten Müller, Dimitris Papageorgiou, Monika Mauermann, Jeroen Krijgsveld, Robert B. Russell, David W. Ellison, Stefan M. Pfister, Kristian W. Pajtler, Marcel Kool

    Veröffentlicht 2019
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  4. 4
    Next Generation Sequencing and Pediatric Brain Tumors: Detection of Cancer Predisposition Syndromes in Patients and Their Families

    Next Generation Sequencing and Pediatric Brain Tumors: Detection of Cancer Predisposition Syndromes in Patients and Their Families von Kerstin Grund, Dominik Sturm, Christian Sutter, Felix Sahm, Katrin Hinderhofer, Christian P. Kratz, Daniel Schrimpf, Andreas von Deimling, Kristian W. Pajtler, David Jones, Stefan M. Pfister, Nicola Dikow

    Veröffentlicht 2017
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  5. 5
    cIMPACT‐NOW update 7: advancing the molecular classification of ependymal tumors

    cIMPACT‐NOW update 7: advancing the molecular classification of ependymal tumors von David W. Ellison, Kenneth Aldape, David Capper, Maryam Fouladi, Mark R. Gilbert, Richard J. Gilbertson, Cynthia Hawkins, Thomas E. Merchant, Kristian W. Pajtler, Sriram Venneti, David N. Louis

    Veröffentlicht 2020
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  6. 6
    Comparison of spatial transcriptomics technologies using tumor cryosections

    Comparison of spatial transcriptomics technologies using tumor cryosections von Anne Rademacher, Alik Huseynov, Michele Bortolomeazzi, Sina Jasmin Wille, Sabrina Schumacher, Pooja Sant, Denise Keitel, Konstantin Okonechnikov, David R. Ghasemi, Kristian W. Pajtler, Jan‐Philipp Mallm, Karsten Rippe

    Veröffentlicht 2024
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  7. 7
    Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas

    Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas von Lara Pohl, Maximilian Leitheiser, Denise Obrecht, Leonille Schweizer, Annika K. Wefers, Alicia Eckhardt, Mark Raffeld, Dominik Sturm, Kristian W. Pajtler, Stefan Rutkowski, Kohei Fukuoka, Koichi Ichimura, Michael Bockmayr, Ulrich Schüller

    Veröffentlicht 2024
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  8. 8
    Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

    Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas von Annette Künkele, Katleen De Preter, Lukas C. Heukamp, T. Thor, Kristian W. Pajtler, Wolfgang Hartmann, Michel Mittelbronn, Michael A. Grotzer, Hedwig E. Deubzer, Frank Speleman, Alexander Schramm, Angelika Eggert, Johannes H. Schulte

    Veröffentlicht 2012
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  9. 9
    Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk

    Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk von Anita Villani, Mary‐Louise C. Greer, Jennifer M. Kalish, Akira Nakagawara, Katherine L. Nathanson, Kristian W. Pajtler, Stefan M. Pfister, Michael F. Walsh, Jonathan D. Wasserman, Kristin Zelley, Christian P. Kratz

    Veröffentlicht 2017
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  10. 10
    Neuroblastoma Predisposition and Surveillance—An Update from the 2023 AACR Childhood Cancer Predisposition Workshop

    Neuroblastoma Predisposition and Surveillance—An Update from the 2023 AACR Childhood Cancer Predisposition Workshop von Junne Kamihara, Lisa Diller, William D. Foulkes, Orli Michaeli, Yoshiko Nakano, Kristian W. Pajtler, Melissa R. Perrino, Sarah Scollon, Douglas R. Stewart, Stephan D. Voss, Rosanna Weksberg, Jordan R. Hansford, Garrett M. Brodeur

    Veröffentlicht 2024
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  11. 11
    Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

    Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy von Johannes H. Schulte, Soyoung Lim, Alexander Schramm, Nicolaus Friedrichs, Jan Köster, Rogier Versteeg, Ingrid Øra, Kristian W. Pajtler, Ludger Klein‐Hitpaß, Steffi Kuhfittig-Kulle, Eric Metzger, Roland Schüle, Angelika Eggert, Reinhard Buettner, Jutta Kirfel

    Veröffentlicht 2009
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  12. 12
    Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis

    Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis von Frank Szulzewsky, Sonali Arora, Pia Hoellerbauer, Claire King, Erica Nathan, Marina Chan, Patrick J. Cimino, Tatsuya Ozawa, Daisuke Kawauchi, Kristian W. Pajtler, Richard J. Gilbertson, Patrick J. Paddison, Valeri Vasioukhin, Taranjit S. Gujral, Eric C. Holland

    Veröffentlicht 2020
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  13. 13
    SIOP Ependymoma I: Final results, long-term follow-up, and molecular analysis of the trial cohort—A BIOMECA Consortium Study

    SIOP Ependymoma I: Final results, long-term follow-up, and molecular analysis of the trial cohort—A BIOMECA Consortium Study von Timothy Ritzmann, Rebecca Chapman, John‐Paul Kilday, Nicky Thorp, Piergiorgio Modena, Robert A. Dineen, Donald Macarthur, Conor Mallucci, T. Jaspan, Kristian W. Pajtler, Marzia Giagnacovo, Thomas S. Jacques, Simon Paine, David W. Ellison, Éric Bouffet, Richard G. Grundy

    Veröffentlicht 2022
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  14. 14
    Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling

    Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling von Konstantin Okonechnikov, David R. Ghasemi, Daniel Schrimpf, Svenja Tonn, Martin Mynarek, Jan Köster, Till Milde, Tuyu Zheng, Philipp Sievers, Felix Sahm, David Jones, Andreas von Deimling, Stefan M. Pfister, Marcel Kool, Kristian W. Pajtler, Andrey Korshunov

    Veröffentlicht 2025
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  15. 15
    High <i>ALK</i> Receptor Tyrosine Kinase Expression Supersedes <i>ALK</i> Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma

    High <i>ALK</i> Receptor Tyrosine Kinase Expression Supersedes <i>ALK</i> Mutation as a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma von Johannes H. Schulte, Hagen S. Bachmann, Bent Brockmeyer, Katleen De Preter, André Oberthür, Sandra Ackermann, Yvonne Kahlert, Kristian W. Pajtler, Jessica Theißen, Frank Westermann, Jo Vandesompele, Frank Speleman, Frank Berthold, Angelika Eggert, Benedikt Brors, Barbara Hero, Alexander Schramm, Matthias Fischer

    Veröffentlicht 2011
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  16. 16
    Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood

    Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood von Jonathan D. Wasserman, Gail E. Tomlinson, Harriet Druker, Junne Kamihara, Wendy Kohlmann, Christian P. Kratz, Katherine L. Nathanson, Kristian W. Pajtler, Andreu Parareda, Surya P. Rednam, Lisa J. States, Anita Villani, Michael F. Walsh, Kristin Zelley, Joshua D. Schiffman

    Veröffentlicht 2017
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  17. 17
    Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging

    Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging von Mélanie Pagès, Kristian W. Pajtler, Stéphanie Puget, David Castel, Nathalie Boddaert, Arnault Tauziède‐Espariat, Stéphanie Picot, Marie‐Anne Debily, Marcel Kool, David Capper, Christian Sainte‐Rose, Fabrice Chrétien, Stefan M. Pfister, Torsten Pietsch, Jacques Grill, Pascale Varlet, Felipe Andreiuolo

    Veröffentlicht 2018
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  18. 18
    The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models

    The GSK461364 PLK1 inhibitor exhibits strong antitumoral activity in preclinical neuroblastoma models von Kristian W. Pajtler, Natalie Sadowski, Sandra Ackermann, Kristina Althoff, K Schönbeck, Katharina Batzke, Simon Schäfers, Andrea Odersky, Lukas C. Heukamp, Kathy Astrahantseff, Annette Künkele, Hedwig E. Deubzer, Alexander Schramm, Annika Sprüssel, Theresa Thor, Sven Lindner, Angelika Eggert, Matthias Fischer, Johannes H. Schulte

    Veröffentlicht 2016
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  19. 19
    DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment

    DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment von Hendrik Witt, Dorothee Gramatzki, Bettina Hentschel, Kristian W. Pajtler, Jörg Felsberg, Gabriele Schackert, Markus Löffler, David Capper, Felix Sahm, Martin Sill, Andreas von Deimling, Marcel Kool, Ulrich Herrlinger, Manfred Westphal, Torsten Pietsch, Guido Reifenberger, Stefan M. Pfister, Jörg C. Tonn, Michael Weller

    Veröffentlicht 2018
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  20. 20
    Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group

    Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group von Michael C. Frühwald, Karolina Nemes, Heidrun Boztug, Marie-Claire Cornips, D. Gareth Evans, Roula Farah, Stavros Glentis, Mette Jorgensen, K. Katsibardi, Steffen Hirsch, Kirsi Jahnukainen, Iris Kventsel, Kornelius Kerl, Christian P. Kratz, Kristian W. Pajtler, Uwe Kordes, Vita Ridola, Eveline Stutz, Franck Bourdeaut

    Veröffentlicht 2021
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