Search Results - Kristen McEachern

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  1. 1
    The Pim-1 Protein Kinase Is an Important Regulator of MET Receptor Tyrosine Kinase Levels and Signaling

    The Pim-1 Protein Kinase Is an Important Regulator of MET Receptor Tyrosine Kinase Levels and Signaling by Bo Cen, Ying Xiong, Jin H. Song, Sandeep Mahajan, Rachel DuPont, Kristen McEachern, Daniel J. DeAngelo, Jorge E. Cortés, Mark D. Minden, Allen Ebens, Alice S. Mims, Amanda C. LaRue, Andrew S. Kraft

    Published 2014
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  2. 2
    Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers

    Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers by Jorge E. Cortés, Kenji Tamura, Daniel J. DeAngelo, Johann S. de Bono, David Lorente, Mark D. Minden, Geoffrey L. Uy, Hagop M. Kantarjian, Lisa S. Chen, Varsha Gandhi, Robert Godin, Karen Keating, Kristen McEachern, Karthick Vishwanathan, J. Elizabeth Pease, Emma Dean

    Published 2018
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  3. 3
    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake by Álvaro de Mingo Pulido, Kay Hänggi, Daiana P. Celias, Alycia Gardner, Jie Li, Bruna M. Batista Bittencourt, Eslam Mohamed, Jimena Trillo-Tinoco, Olabisi Osunmakinde, R Jiménez Peña, Alexis Onimus, Tsuneyasu Kaisho, Johanna K. Kaufmann, Kristen McEachern, Hatem Soliman, Vincent C. Luca, Paulo C. Rodrı́guez, Xiaoqing Yu, Brian Ruffell

    Published 2021
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  4. 4
    AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia

    AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia by Erika Krasnickas Keeton, Kristen McEachern, Keith S. Dillman, Sangeetha Palakurthi, Yichen Cao, Michael Grondine, Surinder Kaur, Suping Wang, Yuching Chen, Allan Wu, Minhui Shen, Francis D. Gibbons, Michelle L. Lamb, Xiaolan Zheng, Richard M. Stone, Daniel J. DeAngelo, Leonidas C. Platanias, Les A. Dakin, Huawei Chen, Paul D. Lyne, Dennis Huszar

    Published 2013
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  5. 5
    The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

    The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors by Michael Hedvat, Dennis Huszar, Andreas Herrmann, Joseph M. Gozgit, Anne Schroeder, Adam Sheehy, Ralf Buettner, David A. Proia, Claudia Kowolik, Xin Hong, Brian Armstrong, Geraldine Bebernitz, Shaobu Weng, Lin Wang, Minwei Ye, Kristen McEachern, Huawei Chen, Deborah Morosini, Kirsten Bell, Marat Alimzhanov, Stephanos Ioannidis, Patricia McCoon, Zhu Cao, Hua Yu, Richard Jove, Michael Zinda

    Published 2009
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  6. 6
    Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis

    Expression Analysis and Significance of PD-1, LAG-3, and TIM-3 in Human Non–Small Cell Lung Cancer Using Spatially Resolved and Multiparametric Single-Cell Analysis by Ila Datar, Miguel F. Sanmamed, Jun Wang, Brian S. Henick, Jungmin Choi, Ti Badri, Weilai Dong, Nikita Mani, Maria Toki, Luis D. Mejías, María D. Lozano, Jose Luis Pérez‐Gracia, Vamsidhar Velcheti, Matthew D. Hellmann, Justin F. Gainor, Kristen McEachern, David W. Jenkins, Konstantinos Syrigos, Katerina Politi, Scott Gettinger, David L. Rimm, Roy S. Herbst, Ignacio Melero, Lieping Chen, Kurt A. Schalper

    Published 2019
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  7. 7
    PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

    PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer by Fara Brasó‐Maristany, Simone Filosto, Steven Catchpole, Rebecca Marlow, Jelmar Quist, Erika Francesch-Domenech, Darren A Plumb, Leila Zakka, Patrycja Gazińska, Gianmaria Liccardi, Pascal Meier, Albert Gris‐Oliver, Maggie C.U. Cheang, Anna Perdrix-Rosell, Manar Shafat, Elodie Noël, Nirmesh Patel, Kristen McEachern, Maurizio Scaltriti, Pau Castel, Farzana Noor, Richard Buus, Sumi Mathew, Johnathan Watkins, Violeta Serra, Pierfrancesco Marra, Anita Grigoriadis, Andrew Tutt

    Published 2016
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