Search Results - Kristel Kemper

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  1. 1
    Molecular identification and targeting of colorectal cancer stem cells.

    Molecular identification and targeting of colorectal cancer stem cells. by Kristel Kemper, Catarina Grandela, Jan Paul Medema

    Published 2010
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  2. 2
    Cancer stem cells – old concepts, new insights

    Cancer stem cells – old concepts, new insights by Louis Vermeulen, Martin R. Sprick, Kristel Kemper, Giorgio Stassi, Jan Paul Medema

    Published 2008
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  3. 3
    Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid Tumors

    Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid Tumors by Jim Middelburg, Kristel Kemper, Patrick Engelberts, Aran F. Labrijn, Janine Schuurman, Thorbald van Hall

    Published 2021
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  4. 4
    Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells

    Monoclonal Antibodies Against Lgr5 Identify Human Colorectal Cancer Stem Cells by Kristel Kemper, Pramudita R. Prasetyanti, Wim de Lau, Hans M. Rodermond, Hans Clevers, Jan Paul Medema

    Published 2012
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  5. 5
    Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer

    Cyclooxygenase-2 Inhibition Inhibits c-Met Kinase Activity and Wnt Activity in Colon Cancer by Jurriaan B. Tuynman, Louis Vermeulen, Elles M. J. Boon, Kristel Kemper, Aeilko H. Zwinderman, Maikel P. Peppelenbosch, D. J. Richel

    Published 2008
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  6. 6
    Cancer vaccines compensate for the insufficient induction of protective tumor-specific immunity of CD3 bispecific antibody therapy

    Cancer vaccines compensate for the insufficient induction of protective tumor-specific immunity of CD3 bispecific antibody therapy by Jim Middelburg, Gaby Schaap, Marjolein Sluijter, Katy A. Lloyd, Vitalijs Ovcinnikovs, Janine Schuurman, Sjoerd H. van der Burg, Kristel Kemper, Thorbald van Hall

    Published 2025
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  7. 7
    Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity

    Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity by Louis Vermeulen, Matilde Todaro, F. de Sousa Mello, Martin R. Sprick, Kristel Kemper, Mileidys Pérez‐Alea, Dick J. Richel, Giorgio Stassi, Jan Paul Medema

    Published 2008
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  8. 8
    The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation

    The AC133 Epitope, but not the CD133 Protein, Is Lost upon Cancer Stem Cell Differentiation by Kristel Kemper, Martin R. Sprick, Martijn de Bree, Alessandro Scopelliti, Louis Vermeulen, Maarten Hoek, Jurrit Zeilstra, Steven T. Pals, Huseyin Mehmet, Giorgio Stassi, Jan Paul Medema

    Published 2010
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  9. 9
    Mutations in the Ras–Raf Axis Underlie the Prognostic Value of CD133 in Colorectal Cancer

    Mutations in the Ras–Raf Axis Underlie the Prognostic Value of CD133 in Colorectal Cancer by Kristel Kemper, Miranda Versloot, Katherine Cameron, Selçuk Çolak, Felipe de Sousa e Melo, Joan H. de Jong, Joanne Bleackley, Louis Vermeulen, Rogier Versteeg, Jan Köster, Jan Paul Medema

    Published 2012
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  10. 10
    Cancer drug addiction is relayed by an ERK2-dependent phenotype switch

    Cancer drug addiction is relayed by an ERK2-dependent phenotype switch by Xiangjun Kong, Thomas Kuilman, Aida Shahrabi, Julia Boshuizen, Kristel Kemper, Ji-Ying Song, Hans W.M. Niessen, Elisa A. Rozeman, Marnix H. Geukes Foppen, Christian U. Blank, Daniel S. Peeper

    Published 2017
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  11. 11
    Targeting <scp>CDK</scp> 2 overcomes melanoma resistance against <scp>BRAF</scp> and Hsp90 inhibitors

    Targeting <scp>CDK</scp> 2 overcomes melanoma resistance against <scp>BRAF</scp> and Hsp90 inhibitors by Alireza Azimi, Stefano Caramuta, Brinton Seashore‐Ludlow, Johan Boström, Jonathan L. Robinson, Fredrik Edfors, Rainer Tuominen, Kristel Kemper, Oscar Krijgsman, Daniel S. Peeper, Jens Nielsen, Johan Hansson, Suzanne Egyházi Brage, Mikael Altun, Mathias Uhlén, Gianluca Maddalo

    Published 2018
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  12. 12
    High-Throughput Assessment of Kinome-wide Activation States

    High-Throughput Assessment of Kinome-wide Activation States by Thierry Schmidlin, Donna O. Debets, Charlotte A. G. H. van Gelder, Kelly E. Stecker, Stamatia Rontogianni, Bart L. van den Eshof, Kristel Kemper, Esther H. Lips, Maartje van den Biggelaar, Daniel S. Peeper, Albert J. R. Heck, Maarten Altelaar

    Published 2019
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  13. 13
    CopywriteR: DNA copy number detection from off-target sequence data

    CopywriteR: DNA copy number detection from off-target sequence data by Thomas Kuilman, Arno Velds, Kristel Kemper, Marco Ranzani, Lorenzo Bombardelli, Marlous Hoogstraat, Ekaterina Nevedomskaya, Guotai Xu, Julian de Ruiter, Martijn P. Lolkema, Bauke Ylstra, Jos Jonkers, Sven Rottenberg, Lodewyk F.A. Wessels, David J. Adams, Daniel S. Peeper, Oscar Krijgsman

    Published 2015
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  14. 14
    Intra‐ and inter‐tumor heterogeneity in a vemurafenib‐resistant melanoma patient and derived xenografts

    Intra‐ and inter‐tumor heterogeneity in a vemurafenib‐resistant melanoma patient and derived xenografts by Kristel Kemper, Oscar Krijgsman, Paulien Cornelissen‐Steijger, Aida Shahrabi, Fleur Weeber, Ji‐Ying Song, Thomas Kuilman, Daniël J. Vis, Lodewyk F.A. Wessels, Emile E. Voest, Ton N. Schumacher, Christian U. Blank, David J. Adams, John B.A.G. Haanen, Daniel S. Peeper

    Published 2015
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  15. 15
    XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

    XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data by Roelof J.C. Kluin, Kristel Kemper, Thomas Kuilman, Julian R. de Ruiter, Vivek Iyer, Josep V. Forment, Paulien Cornelissen‐Steijger, Iris de Rink, Petra ter Brugge, Ji‐Ying Song, Sjoerd Klarenbeek, Ultan McDermott, Jos Jonkers, Arno Velds, David J. Adams, Daniel S. Peeper, Oscar Krijgsman

    Published 2018
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  16. 16
    T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors

    T-cell stimulating vaccines empower CD3 bispecific antibody therapy in solid tumors by Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy A. Lloyd, Vitalijs Ovcinnikovs, Gijs G. Zom, Renoud J. Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin W. Sandker, Sandra Heskamp, Sjoerd H. van der Burg, Tsolère Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall

    Published 2024
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  17. 17
    Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities

    Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities by Jean‐Philippe Coppé, Miki Mori, Bo Pan, Christina Yau, Denise M. Wolf, Ana Ruiz-Sáenz, Diede Brunen, Anirudh Prahallad, Paulien Cornelissen‐Steijger, Kristel Kemper, Christian Posch, Changjun Wang, Courtney A. Dreyer, Oscar Krijgsman, Pei Rong Evelyn Lee, Zhongzhong Chen, Daniel S. Peeper, Mark M. Moasser, René Bernards, Laura van ‘t Veer

    Published 2019
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  18. 18
    Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

    Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma by Judith M. Müller, Oscar Krijgsman, Jennifer Tsoi, Lídia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patrícia A. Possik, Paulien Cornelissen‐Steijger, Marnix H. Geukes Foppen, Kristel Kemper, Colin R. Goding, Ultan McDermott, Christian U. Blank, John B.A.G. Haanen, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Daniel S. Peeper

    Published 2014
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  19. 19
    BRAF V600E Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts

    BRAF V600E Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts by Kristel Kemper, Oscar Krijgsman, Xiangjun Kong, Paulien Cornelissen‐Steijger, Aida Shahrabi, Fleur Weeber, Daphne van der Velden, Onno B. Bleijerveld, Thomas Kuilman, Roelof J.C. Kluin, Chong Sun, Emile E. Voest, Young Seok Ju, Ton N. Schumacher, Maarten Altelaar, Ultan McDermott, David J. Adams, Christian U. Blank, John B.A.G. Haanen, Daniel S. Peeper

    Published 2016
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  20. 20
    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma

    Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma by Yong Yu, Kolja Schleich, Bin Yue, Sujuan Ji, Philipp Lohneis, Kristel Kemper, Mark R. Silvis, Nouar Qutob, Ellen van Rooijen, Melanie Werner‐Klein, Lianjie Li, Dhriti Dhawan, Svenja Meierjohann, Maurice Reimann, Abdel Elkahloun, Steffi Treitschke, Bernd Dörken, Christian Speck, Frédérick A. Mallette, Leonard I. Zon, Sheri L. Holmen, Daniel S. Peeper, Yardena Samuels, Clemens A. Schmitt, Soyoung Lee

    Published 2018
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