Resultats de la cerca - Konstantin Khrapko

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  1. 1
    Mitochondrial DNA mutations and aging: devils in the details?

    Mitochondrial DNA mutations and aging: devils in the details? per Konstantin Khrapko, Jan Vijg

    Publicat 2008
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  2. 2
    Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos

    Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos per Dori C. Woods, Konstantin Khrapko, Jonathan L. Tilly

    Publicat 2018
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  3. 3
    Fidelity and Mutational Spectrum of <i>Pfu</i> DNA Polymerase on a Human Mitochondrial DNA Sequence

    Fidelity and Mutational Spectrum of <i>Pfu</i> DNA Polymerase on a Human Mitochondrial DNA Sequence per Paulo André, Andrea Kim, Konstantin Khrapko, William G. Thilly

    Publicat 1997
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  4. 4
    A microRNA array reveals extensive regulation of microRNAs during brain development

    A microRNA array reveals extensive regulation of microRNAs during brain development per Anna M. Krichevsky, Kevin S. King, Christine P. Donahue, Konstantin Khrapko, Kenneth S. Kosik

    Publicat 2003
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  5. 5
    Mitochondrial mutational spectra in human cells and tissues

    Mitochondrial mutational spectra in human cells and tissues per Konstantin Khrapko, Hilary A. Coller, Paulo André, Xiao-Cheng Li, John S. Hanekamp, William G. Thilly

    Publicat 1997
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  6. 6
    Distribution of high mobility group proteins 1/2,E and 14/17 and linker histones H1 and H5 on transcribed and non-transcribed regions of chicken erythrocyte chromatin

    Distribution of high mobility group proteins 1/2,E and 14/17 and linker histones H1 and H5 on transcribed and non-transcribed regions of chicken erythrocyte chromatin per Yuri V. Postnikov, V.V. Shick, A. V. Belyavsky, Konstantin Khrapko, Konstantin Brodolin, Tatjana A. Nikolskaya, A.D. Mirzabekov

    Publicat 1991
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  7. 7
    Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis

    Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis per Adeel Safdar, Sofia Annis, Yevgenya Kraytsberg, Chloe A. Laverack, Ayesha Saleem, Konstantin Popadin, Dori C. Woods, Jonathan L. Tilly, Konstantin Khrapko

    Publicat 2016
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  8. 8
    Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues

    Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues per Ekaterina Nekhaeva, Natalya D. Bodyak, Yevgenya Kraytsberg, Sean McGrath, Nathalie J. van Orsouw, Anna Pluzhnikov, Jeanne Y. Wei, Jan Vijg, Konstantin Khrapko

    Publicat 2002
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  9. 9
    A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics

    A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics per J. Macdonald, Alisha M. Bothun, Sofia Annis, Hannah C. Sheehan, Somak Ray, Yuanwei Gao, Alexander R. Ivanov, Konstantin Khrapko, Jonathan L. Tilly, Dori C. Woods

    Publicat 2019
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  10. 10
    Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions

    Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions per Konstantin Khrapko, Natalya D. Bodyak, William G. Thilly, Nathalie J. van Orsouw, Xianfeng Zhang, Hilary A. Coller, Thomas T. Perls, Melissa P. Upton, Jan Vijg, Jeanne Y. Wei

    Publicat 1999
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  11. 11
    Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis

    Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis per G. Campbell, Yevgenya Kraytsberg, Kim J. Krishnan, Nobuhiko Ohno, Iryna Ziabreva, Amy K. Reeve, Bruce D. Trapp, Jia Newcombe, Richard Reynolds, Hans Lassmann, Konstantin Khrapko, Douglass M. Turnbull, Don J. Mahad

    Publicat 2012
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  12. 12
    In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

    In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells per Giovanni Amabile, Robert S. Welner, César Nombela‐Arrieta, Anna Morena D’Alise, Annalisa Di Ruscio, Alexander K. Ebralidze, Yevgenya Kraytsberg, Min Ye, Olivier Kocher, Donna Neuberg, Konstantin Khrapko, Leslie E. Silberstein, Daniel G. Tenen

    Publicat 2012
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  13. 13
    Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing

    Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing per Laura C. Greaves, Marco Nooteboom, Joanna L. Elson, Helen Tuppen, Geoffrey A. Taylor, Daniel M. Commane, Ramesh Arasaradnam, Konstantin Khrapko, Robert W. Taylor, Thomas B. L. Kirkwood, John C. Mathers, Douglass M. Turnbull

    Publicat 2014
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  14. 14
    Deciphering the Foundations of Mitochondrial Mutational Spectra: Replication-Driven and Damage-Induced Signatures Across Chordate Classes

    Deciphering the Foundations of Mitochondrial Mutational Spectra: Replication-Driven and Damage-Induced Signatures Across Chordate Classes per Dmitrii Iliushchenko, Bogdan Efimenko, Alina G. Mikhailova, Victor Shamanskiy, Murat Saparbaev, Bakhyt Matkarimov, Ilya Mazunin, Alexandr Voronka, Dmitry A. Knorre, Wolfram S. Kunz, Philipp Kapranov, Stepan Denisov, Jacques Fellay, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin

    Publicat 2025
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  15. 15
    RETRACTED ARTICLE:Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice

    RETRACTED ARTICLE:Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice per Adeel Safdar, Konstantin Khrapko, James M. Flynn, Ayesha Saleem, Michael De Lisio, Adam P. W. Johnston, Yevgenya Kratysberg, Imtiaz A. Samjoo, Yu Kitaoka, Daniel I. Ogborn, Jonathan P. Little, Sandeep Raha, Gianni Parise, Mahmood Akhtar, Bart P. Hettinga, Glenn C. Rowe, Zoltàn Arany, Tomas A. Prolla, Mark A. Tarnopolsky

    Publicat 2015
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  16. 16
    A mitochondria-specific mutational signature of aging: increased rate of A &amp;gt; G substitutions on the heavy strand

    A mitochondria-specific mutational signature of aging: increased rate of A &amp;gt; G substitutions on the heavy strand per Alina G. Mikhailova, Alina A. Mikhailova, Kristina Ushakova, Evgeny O Tretiakov, Dmitrii Iliushchenko, Victor Shamansky, V.V. Lobanova, Ivan Kozenkov, Bogdan Efimenko, Andrey A. Yurchenko, Elena Kozenkova, Evgeny M. Zdobnov, Vsevolod J. Makeev, V. A. Yurov, Masashi Tanaka, Irina Gostimskaya, Zoë Fleischmann, Sofia Annis, Melissa Franco, Kevin Wasko, Stepan S. Denisov, Wolfram S. Kunz, Dmitry A. Knorre, Ilya Mazunin, Sergey I. Nikolaev, Jacques Fellay, Alexandre Reymond, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin

    Publicat 2022
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