نتائج البحث - Konstantin Khrapko
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Mitochondrial DNA mutations and aging: devils in the details? حسب Konstantin Khrapko, Jan Vijg
منشور في 2008Revisão -
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Distribution of high mobility group proteins 1/2,E and 14/17 and linker histones H1 and H5 on transcribed and non-transcribed regions of chicken erythrocyte chromatin حسب Yuri V. Postnikov, V.V. Shick, A. V. Belyavsky, Konstantin Khrapko, Konstantin Brodolin, Tatjana A. Nikolskaya, A.D. Mirzabekov
منشور في 1991Artigo -
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Amelioration of premature aging in mtDNA mutator mouse by exercise: the interplay of oxidative stress, PGC-1α, p53, and DNA damage. A hypothesis حسب Adeel Safdar, Sofia Annis, Yevgenya Kraytsberg, Chloe A. Laverack, Ayesha Saleem, Konstantin Popadin, Dori C. Woods, Jonathan L. Tilly, Konstantin Khrapko
منشور في 2016Revisão -
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A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics حسب J. Macdonald, Alisha M. Bothun, Sofia Annis, Hannah C. Sheehan, Somak Ray, Yuanwei Gao, Alexander R. Ivanov, Konstantin Khrapko, Jonathan L. Tilly, Dori C. Woods
منشور في 2019Artigo -
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Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions حسب Konstantin Khrapko, Natalya D. Bodyak, William G. Thilly, Nathalie J. van Orsouw, Xianfeng Zhang, Hilary A. Coller, Thomas T. Perls, Melissa P. Upton, Jan Vijg, Jeanne Y. Wei
منشور في 1999Artigo -
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Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis حسب G. Campbell, Yevgenya Kraytsberg, Kim J. Krishnan, Nobuhiko Ohno, Iryna Ziabreva, Amy K. Reeve, Bruce D. Trapp, Jia Newcombe, Richard Reynolds, Hans Lassmann, Konstantin Khrapko, Douglass M. Turnbull, Don J. Mahad
منشور في 2012Artigo -
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In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells حسب Giovanni Amabile, Robert S. Welner, César Nombela‐Arrieta, Anna Morena D’Alise, Annalisa Di Ruscio, Alexander K. Ebralidze, Yevgenya Kraytsberg, Min Ye, Olivier Kocher, Donna Neuberg, Konstantin Khrapko, Leslie E. Silberstein, Daniel G. Tenen
منشور في 2012Artigo -
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Clonal Expansion of Early to Mid-Life Mitochondrial DNA Point Mutations Drives Mitochondrial Dysfunction during Human Ageing حسب Laura C. Greaves, Marco Nooteboom, Joanna L. Elson, Helen Tuppen, Geoffrey A. Taylor, Daniel M. Commane, Ramesh Arasaradnam, Konstantin Khrapko, Robert W. Taylor, Thomas B. L. Kirkwood, John C. Mathers, Douglass M. Turnbull
منشور في 2014Artigo -
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Deciphering the Foundations of Mitochondrial Mutational Spectra: Replication-Driven and Damage-Induced Signatures Across Chordate Classes حسب Dmitrii Iliushchenko, Bogdan Efimenko, Alina G. Mikhailova, Victor Shamanskiy, Murat Saparbaev, Bakhyt Matkarimov, Ilya Mazunin, Alexandr Voronka, Dmitry A. Knorre, Wolfram S. Kunz, Philipp Kapranov, Stepan Denisov, Jacques Fellay, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin
منشور في 2025Artigo -
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RETRACTED ARTICLE:Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice حسب Adeel Safdar, Konstantin Khrapko, James M. Flynn, Ayesha Saleem, Michael De Lisio, Adam P. W. Johnston, Yevgenya Kratysberg, Imtiaz A. Samjoo, Yu Kitaoka, Daniel I. Ogborn, Jonathan P. Little, Sandeep Raha, Gianni Parise, Mahmood Akhtar, Bart P. Hettinga, Glenn C. Rowe, Zoltàn Arany, Tomas A. Prolla, Mark A. Tarnopolsky
منشور في 2015Artigo -
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A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand حسب Alina G. Mikhailova, Alina A. Mikhailova, Kristina Ushakova, Evgeny O Tretiakov, Dmitrii Iliushchenko, Victor Shamansky, V.V. Lobanova, Ivan Kozenkov, Bogdan Efimenko, Andrey A. Yurchenko, Elena Kozenkova, Evgeny M. Zdobnov, Vsevolod J. Makeev, V. A. Yurov, Masashi Tanaka, Irina Gostimskaya, Zoë Fleischmann, Sofia Annis, Melissa Franco, Kevin Wasko, Stepan S. Denisov, Wolfram S. Kunz, Dmitry A. Knorre, Ilya Mazunin, Sergey I. Nikolaev, Jacques Fellay, Alexandre Reymond, Konstantin Khrapko, Konstantin Gunbin, Konstantin Popadin
منشور في 2022Artigo
أدوات البحث:
موضوعات ذات صلة
Biology
Gene
Genetics
Mitochondrial DNA
Cell biology
Mutation
Mitochondrion
Molecular biology
DNA
Mutant
Point mutation
Somatic cell
Genome
Mutagenesis
Biochemistry
Computational biology
DNA damage
DNA repair
Gene expression
Germline
Heteroplasmy
Human mitochondrial genetics
Phenotype
Polymerase
Stem cell
Acoustics
Adult stem cell
Ageing
Archaea
Bioinformatics