Søgeresultater - Knoechel, Birgit

Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes af Knoechel, Birgit, Lohr, Jens G.

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Balance of Th1 and Th17 effector and peripheral regulatory T cells af Lohr, Jens, Knoechel, Birgit, Caretto, David, Abbas, Abul K.

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Comprehensive characterization of circulating and bone marrow-derived multiple myeloma cells at MRD af Waldschmidt, Johannes M., Anand, Praveen, Knoechel, Birgit, Lohr, Jens G.

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Tracking myeloma tumor DNA in peripheral blood af Waldschmidt, Johannes M., Vijaykumar, Tushara, Knoechel, Birgit, Lohr, Jens G.

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Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen af Knoechel, Birgit, Lohr, Jens, Kahn, Estelle, Bluestone, Jeffrey A., Abbas, Abul K.

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Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease af Lohr, Jens, Knoechel, Birgit, Wang, Jing Jing, Villarino, Alejandro V., Abbas, Abul K.

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Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma af Mandelbaum, Joseph, Shestopalov, Ilya A., Henderson, Rachel E., Chau, Nicole G., Knoechel, Birgit, Wick, Michael J., Zon, Leonard I.

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Peptidomimetic blockade of MYB in acute myeloid leukemia af Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex

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Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case af Knoechel, Birgit, Bhatt, Ami, Pan, Li, Pedamallu, Chandra S., Severson, Eric, Gutierrez, Alejandro, Dorfman, David M., Kuo, Frank C., Kluk, Michael, Kung, Andrew L., Zweidler-McKay, Patrick, Meyerson, Matthew, Blacklow, Stephen C., DeAngelo, Daniel J., Aster, Jon C.

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Genetic interrogation of circulating multiple myeloma cells at single cell resolution af Lohr, Jens G., Kim, Sora, Gould, Joshua, Knoechel, Birgit, Drier, Yotam, Cotton, Matthew J., Gray, Daniel, Birrer, Nicole, Wong, Bang, Ha, Gavin, Zhang, Cheng-Zhong, Guo, Guangwu, Meyerson, Matthew, Yee, Andrew J., Boehm, Jesse S., Raje, Noopur, Golub, Todd R.

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia af Yashiro-Ohtani, Yumi, Wang, Hongfang, Zang, Chongzhi, Arnett, Kelly L., Bailis, Will, Ho, Yugong, Knoechel, Birgit, Lanauze, Claudia, Louis, Lumena, Forsyth, Katherine S., Chen, Sujun, Chung, Yoonjie, Schug, Jonathan, Blobel, Gerd A., Liebhaber, Stephen A., Bernstein, Bradley E., Blacklow, Stephen C., Liu, Xiaole Shirley, Aster, Jon C., Pear, Warren S.

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Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma af Frede, Julia, Anand, Praveen, Sotudeh, Noori, Pinto, Ricardo A., Nair, Monica S., Stuart, Hannah, Yee, Andrew J., Vijaykumar, Tushara, Waldschmidt, Johannes M., Potdar, Sayalee, Kloeber, Jake A., Kokkalis, Antonis, Dimitrova, Valeriya, Mann, Mason, Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.

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Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy af Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Getz, Gad, Golub, Todd R.

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EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma af Riggi, Nicolò, Knoechel, Birgit, Gillespie, Shawn M., Rheinbay, Esther, Boulay, Gaylor, Suvà, Mario L., Rossetti, Nikki E., Boonseng, Wannaporn E., Oksuz, Ozgur, Cook, Edward B., Formey, Aurélie, Patel, Anoop, Gymrek, Melissa, Thapar, Vishal, Deshpande, Vikram, Ting, David T., Hornicek, Francis J., Nielsen, G. Petur, Stamenkovic, Ivan, Aryee, Martin J., Bernstein, Bradley E., Rivera, Miguel N.

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Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma af Stoeck, Alexander, Lejnine, Serguei, Truong, Andrew, Pan, Li, Wang, Hongfang, Zang, Chongzhi, Yuan, Jing, Ware, Chris, MacLean, John, Garrett-Engele, Philip W, Kluk, Michael, Laskey, Jason, Haines, Brian B., Moskaluk, Christopher, Zawel, Leigh, Fawell, Stephen, Gilliland, Gary, Zhang, Theresa, Kremer, Brandon, Knoechel, Birgit, Bernstein, Bradley E, Pear, Warren S., Liu, X. Shirley, Aster, Jon C, Sathyanarayanan, Sriram

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An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma af Drier, Yotam, Cotton, Matthew J., Williamson, Kaylyn E., Gillespie, Shawn M., Ryan, Russell J.H., Kluk, Michael J., Carey, Christopher D., Rodig, Scott J., Sholl, Lynette M, Afrogheh, Amir H., Faquin, William C., Queimado, Lurdes, Qi, Jun, Wick, Michael J., El-Naggar, Adel K., Bradner, James E., Moskaluk, Christopher A., Aster, Jon C., Knoechel, Birgit, Bernstein, Bradley E.

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Genomic discovery and clonal tracking in multiple myeloma by cell free DNA sequencing af Guo, Guangwu, Raje, Noopur S., Seifer, Charles, Kloeber, Jake, Isenhart, Randi, Ha, Gavin, Yee, Andrew J., O’Donnell, Elizabeth K., Tai, Yu-Tzu, Richardson, Paul G., Bianchi, Giada, Laubach, Jacob P., Warren, Diane, Gemme, Erica, Voisine, Jordan, Frede, Julia, Kokkalis, Antonis, Yun, Huiyoung, Dimitrova, Valeriya, Vijaykumar, Tushara, Meyerson, Matthew, Munshi, Nikhil, Anderson, Kenneth C., Knoechel, Birgit, Lohr, Jens G.

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Single-cell profiling reveals metabolic reprogramming as a resistance mechanism in BRAF-mutated multiple myeloma af Waldschmidt, Johannes M., Kloeber, Jake A., Anand, Praveen, Frede, Julia, Kokkalis, Antonis, Dimitrova, Valeriya, Potdar, Sayalee, Nair, Monica S., Vijaykumar, Tushara, Im, Nam Gyu, Guillaumet-Adkins, Amy, Chopra, Nitish, Stuart, Hannah, Budano, Lillian, Sotudeh, Noori, Guo, Guangwu, Grassberger, Clemens, Yee, Andrew J., Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.

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Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia af Montanaro, Anna, Kitara, Samuel, Cerretani, Elisa, Marchesini, Matteo, Rompietti, Chiara, Pagliaro, Luca, Gherli, Andrea, Su, Angela, Minchillo, Maria Laura, Caputi, Mariafrancesca, Fioretzaki, Rodanthi, Lorusso, Bruno, Ross, Linda, Alexe, Gabriela, Masselli, Elena, Marozzi, Marina, Rizzi, Federica Maria Angela, La Starza, Roberta, Mecucci, Cristina, Xiong, Yan, Jin, Jian, Falco, Angela, Knoechel, Birgit, Aversa, Franco, Candini, Olivia, Quaini, Federico, Sportoletti, Paolo, Stegmaier, Kimberly, Roti, Giovanni

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Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL af Anand, Praveen, Guillaumet-Adkins, Amy, Dimitrova, Valeriya, Yun, Huiyoung, Drier, Yotam, Sotudeh, Noori, Rogers, Anna, Ouseph, Madhu M., Nair, Monica, Potdar, Sayalee, Isenhart, Randi, Kloeber, Jake A., Vijaykumar, Tushara, Niu, Leili, Vincent, Tiffaney, Guo, Guangwu, Frede, Julia, Harris, Marian H., Place, Andrew E., Silverman, Lewis B., Teachey, David T., Lane, Andrew A., DeAngelo, Daniel J., Aster, Jon C., Bernstein, Bradley E., Lohr, Jens G., Knoechel, Birgit

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