Resultats de la cerca - Knoechel, Birgit

Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes per Knoechel, Birgit, Lohr, Jens G.

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Balance of Th1 and Th17 effector and peripheral regulatory T cells per Lohr, Jens, Knoechel, Birgit, Caretto, David, Abbas, Abul K.

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Comprehensive characterization of circulating and bone marrow-derived multiple myeloma cells at MRD per Waldschmidt, Johannes M., Anand, Praveen, Knoechel, Birgit, Lohr, Jens G.

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Tracking myeloma tumor DNA in peripheral blood per Waldschmidt, Johannes M., Vijaykumar, Tushara, Knoechel, Birgit, Lohr, Jens G.

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Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen per Knoechel, Birgit, Lohr, Jens, Kahn, Estelle, Bluestone, Jeffrey A., Abbas, Abul K.

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Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease per Lohr, Jens, Knoechel, Birgit, Wang, Jing Jing, Villarino, Alejandro V., Abbas, Abul K.

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Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma per Mandelbaum, Joseph, Shestopalov, Ilya A., Henderson, Rachel E., Chau, Nicole G., Knoechel, Birgit, Wick, Michael J., Zon, Leonard I.

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Peptidomimetic blockade of MYB in acute myeloid leukemia per Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex

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Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case per Knoechel, Birgit, Bhatt, Ami, Pan, Li, Pedamallu, Chandra S., Severson, Eric, Gutierrez, Alejandro, Dorfman, David M., Kuo, Frank C., Kluk, Michael, Kung, Andrew L., Zweidler-McKay, Patrick, Meyerson, Matthew, Blacklow, Stephen C., DeAngelo, Daniel J., Aster, Jon C.

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Genetic interrogation of circulating multiple myeloma cells at single cell resolution per Lohr, Jens G., Kim, Sora, Gould, Joshua, Knoechel, Birgit, Drier, Yotam, Cotton, Matthew J., Gray, Daniel, Birrer, Nicole, Wong, Bang, Ha, Gavin, Zhang, Cheng-Zhong, Guo, Guangwu, Meyerson, Matthew, Yee, Andrew J., Boehm, Jesse S., Raje, Noopur, Golub, Todd R.

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia per Yashiro-Ohtani, Yumi, Wang, Hongfang, Zang, Chongzhi, Arnett, Kelly L., Bailis, Will, Ho, Yugong, Knoechel, Birgit, Lanauze, Claudia, Louis, Lumena, Forsyth, Katherine S., Chen, Sujun, Chung, Yoonjie, Schug, Jonathan, Blobel, Gerd A., Liebhaber, Stephen A., Bernstein, Bradley E., Blacklow, Stephen C., Liu, Xiaole Shirley, Aster, Jon C., Pear, Warren S.

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Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma per Frede, Julia, Anand, Praveen, Sotudeh, Noori, Pinto, Ricardo A., Nair, Monica S., Stuart, Hannah, Yee, Andrew J., Vijaykumar, Tushara, Waldschmidt, Johannes M., Potdar, Sayalee, Kloeber, Jake A., Kokkalis, Antonis, Dimitrova, Valeriya, Mann, Mason, Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.

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Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy per Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Getz, Gad, Golub, Todd R.

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EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma per Riggi, Nicolò, Knoechel, Birgit, Gillespie, Shawn M., Rheinbay, Esther, Boulay, Gaylor, Suvà, Mario L., Rossetti, Nikki E., Boonseng, Wannaporn E., Oksuz, Ozgur, Cook, Edward B., Formey, Aurélie, Patel, Anoop, Gymrek, Melissa, Thapar, Vishal, Deshpande, Vikram, Ting, David T., Hornicek, Francis J., Nielsen, G. Petur, Stamenkovic, Ivan, Aryee, Martin J., Bernstein, Bradley E., Rivera, Miguel N.

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Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma per Stoeck, Alexander, Lejnine, Serguei, Truong, Andrew, Pan, Li, Wang, Hongfang, Zang, Chongzhi, Yuan, Jing, Ware, Chris, MacLean, John, Garrett-Engele, Philip W, Kluk, Michael, Laskey, Jason, Haines, Brian B., Moskaluk, Christopher, Zawel, Leigh, Fawell, Stephen, Gilliland, Gary, Zhang, Theresa, Kremer, Brandon, Knoechel, Birgit, Bernstein, Bradley E, Pear, Warren S., Liu, X. Shirley, Aster, Jon C, Sathyanarayanan, Sriram

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An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma per Drier, Yotam, Cotton, Matthew J., Williamson, Kaylyn E., Gillespie, Shawn M., Ryan, Russell J.H., Kluk, Michael J., Carey, Christopher D., Rodig, Scott J., Sholl, Lynette M, Afrogheh, Amir H., Faquin, William C., Queimado, Lurdes, Qi, Jun, Wick, Michael J., El-Naggar, Adel K., Bradner, James E., Moskaluk, Christopher A., Aster, Jon C., Knoechel, Birgit, Bernstein, Bradley E.

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Genomic discovery and clonal tracking in multiple myeloma by cell free DNA sequencing per Guo, Guangwu, Raje, Noopur S., Seifer, Charles, Kloeber, Jake, Isenhart, Randi, Ha, Gavin, Yee, Andrew J., O’Donnell, Elizabeth K., Tai, Yu-Tzu, Richardson, Paul G., Bianchi, Giada, Laubach, Jacob P., Warren, Diane, Gemme, Erica, Voisine, Jordan, Frede, Julia, Kokkalis, Antonis, Yun, Huiyoung, Dimitrova, Valeriya, Vijaykumar, Tushara, Meyerson, Matthew, Munshi, Nikhil, Anderson, Kenneth C., Knoechel, Birgit, Lohr, Jens G.

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Single-cell profiling reveals metabolic reprogramming as a resistance mechanism in BRAF-mutated multiple myeloma per Waldschmidt, Johannes M., Kloeber, Jake A., Anand, Praveen, Frede, Julia, Kokkalis, Antonis, Dimitrova, Valeriya, Potdar, Sayalee, Nair, Monica S., Vijaykumar, Tushara, Im, Nam Gyu, Guillaumet-Adkins, Amy, Chopra, Nitish, Stuart, Hannah, Budano, Lillian, Sotudeh, Noori, Guo, Guangwu, Grassberger, Clemens, Yee, Andrew J., Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.

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Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia per Montanaro, Anna, Kitara, Samuel, Cerretani, Elisa, Marchesini, Matteo, Rompietti, Chiara, Pagliaro, Luca, Gherli, Andrea, Su, Angela, Minchillo, Maria Laura, Caputi, Mariafrancesca, Fioretzaki, Rodanthi, Lorusso, Bruno, Ross, Linda, Alexe, Gabriela, Masselli, Elena, Marozzi, Marina, Rizzi, Federica Maria Angela, La Starza, Roberta, Mecucci, Cristina, Xiong, Yan, Jin, Jian, Falco, Angela, Knoechel, Birgit, Aversa, Franco, Candini, Olivia, Quaini, Federico, Sportoletti, Paolo, Stegmaier, Kimberly, Roti, Giovanni

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Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL per Anand, Praveen, Guillaumet-Adkins, Amy, Dimitrova, Valeriya, Yun, Huiyoung, Drier, Yotam, Sotudeh, Noori, Rogers, Anna, Ouseph, Madhu M., Nair, Monica, Potdar, Sayalee, Isenhart, Randi, Kloeber, Jake A., Vijaykumar, Tushara, Niu, Leili, Vincent, Tiffaney, Guo, Guangwu, Frede, Julia, Harris, Marian H., Place, Andrew E., Silverman, Lewis B., Teachey, David T., Lane, Andrew A., DeAngelo, Daniel J., Aster, Jon C., Bernstein, Bradley E., Lohr, Jens G., Knoechel, Birgit

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