Canlyniadau Chwilio - Knoechel, Birgit

Genomics of lymphoid malignancies reveal major activation pathways in lymphocytes gan Knoechel, Birgit, Lohr, Jens G.

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Balance of Th1 and Th17 effector and peripheral regulatory T cells gan Lohr, Jens, Knoechel, Birgit, Caretto, David, Abbas, Abul K.

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Comprehensive characterization of circulating and bone marrow-derived multiple myeloma cells at MRD gan Waldschmidt, Johannes M., Anand, Praveen, Knoechel, Birgit, Lohr, Jens G.

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Tracking myeloma tumor DNA in peripheral blood gan Waldschmidt, Johannes M., Vijaykumar, Tushara, Knoechel, Birgit, Lohr, Jens G.

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Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen gan Knoechel, Birgit, Lohr, Jens, Kahn, Estelle, Bluestone, Jeffrey A., Abbas, Abul K.

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Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease gan Lohr, Jens, Knoechel, Birgit, Wang, Jing Jing, Villarino, Alejandro V., Abbas, Abul K.

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Zebrafish blastomere screen identifies retinoic acid suppression of MYB in adenoid cystic carcinoma gan Mandelbaum, Joseph, Shestopalov, Ilya A., Henderson, Rachel E., Chau, Nicole G., Knoechel, Birgit, Wick, Michael J., Zon, Leonard I.

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Peptidomimetic blockade of MYB in acute myeloid leukemia gan Ramaswamy, Kavitha, Forbes, Lauren, Minuesa, Gerard, Gindin, Tatyana, Brown, Fiona, Kharas, Michael G., Krivtsov, Andrei V., Armstrong, Scott A., Still, Eric, de Stanchina, Elisa, Knoechel, Birgit, Koche, Richard, Kentsis, Alex

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Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case gan Knoechel, Birgit, Bhatt, Ami, Pan, Li, Pedamallu, Chandra S., Severson, Eric, Gutierrez, Alejandro, Dorfman, David M., Kuo, Frank C., Kluk, Michael, Kung, Andrew L., Zweidler-McKay, Patrick, Meyerson, Matthew, Blacklow, Stephen C., DeAngelo, Daniel J., Aster, Jon C.

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Genetic interrogation of circulating multiple myeloma cells at single cell resolution gan Lohr, Jens G., Kim, Sora, Gould, Joshua, Knoechel, Birgit, Drier, Yotam, Cotton, Matthew J., Gray, Daniel, Birrer, Nicole, Wong, Bang, Ha, Gavin, Zhang, Cheng-Zhong, Guo, Guangwu, Meyerson, Matthew, Yee, Andrew J., Boehm, Jesse S., Raje, Noopur, Golub, Todd R.

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Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia gan Yashiro-Ohtani, Yumi, Wang, Hongfang, Zang, Chongzhi, Arnett, Kelly L., Bailis, Will, Ho, Yugong, Knoechel, Birgit, Lanauze, Claudia, Louis, Lumena, Forsyth, Katherine S., Chen, Sujun, Chung, Yoonjie, Schug, Jonathan, Blobel, Gerd A., Liebhaber, Stephen A., Bernstein, Bradley E., Blacklow, Stephen C., Liu, Xiaole Shirley, Aster, Jon C., Pear, Warren S.

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Dynamic transcriptional reprogramming leads to immunotherapeutic vulnerabilities in myeloma gan Frede, Julia, Anand, Praveen, Sotudeh, Noori, Pinto, Ricardo A., Nair, Monica S., Stuart, Hannah, Yee, Andrew J., Vijaykumar, Tushara, Waldschmidt, Johannes M., Potdar, Sayalee, Kloeber, Jake A., Kokkalis, Antonis, Dimitrova, Valeriya, Mann, Mason, Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.

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Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy gan Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Getz, Gad, Golub, Todd R.

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EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma gan Riggi, Nicolò, Knoechel, Birgit, Gillespie, Shawn M., Rheinbay, Esther, Boulay, Gaylor, Suvà, Mario L., Rossetti, Nikki E., Boonseng, Wannaporn E., Oksuz, Ozgur, Cook, Edward B., Formey, Aurélie, Patel, Anoop, Gymrek, Melissa, Thapar, Vishal, Deshpande, Vikram, Ting, David T., Hornicek, Francis J., Nielsen, G. Petur, Stamenkovic, Ivan, Aryee, Martin J., Bernstein, Bradley E., Rivera, Miguel N.

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Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma gan Stoeck, Alexander, Lejnine, Serguei, Truong, Andrew, Pan, Li, Wang, Hongfang, Zang, Chongzhi, Yuan, Jing, Ware, Chris, MacLean, John, Garrett-Engele, Philip W, Kluk, Michael, Laskey, Jason, Haines, Brian B., Moskaluk, Christopher, Zawel, Leigh, Fawell, Stephen, Gilliland, Gary, Zhang, Theresa, Kremer, Brandon, Knoechel, Birgit, Bernstein, Bradley E, Pear, Warren S., Liu, X. Shirley, Aster, Jon C, Sathyanarayanan, Sriram

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An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma gan Drier, Yotam, Cotton, Matthew J., Williamson, Kaylyn E., Gillespie, Shawn M., Ryan, Russell J.H., Kluk, Michael J., Carey, Christopher D., Rodig, Scott J., Sholl, Lynette M, Afrogheh, Amir H., Faquin, William C., Queimado, Lurdes, Qi, Jun, Wick, Michael J., El-Naggar, Adel K., Bradner, James E., Moskaluk, Christopher A., Aster, Jon C., Knoechel, Birgit, Bernstein, Bradley E.

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Genomic discovery and clonal tracking in multiple myeloma by cell free DNA sequencing gan Guo, Guangwu, Raje, Noopur S., Seifer, Charles, Kloeber, Jake, Isenhart, Randi, Ha, Gavin, Yee, Andrew J., O’Donnell, Elizabeth K., Tai, Yu-Tzu, Richardson, Paul G., Bianchi, Giada, Laubach, Jacob P., Warren, Diane, Gemme, Erica, Voisine, Jordan, Frede, Julia, Kokkalis, Antonis, Yun, Huiyoung, Dimitrova, Valeriya, Vijaykumar, Tushara, Meyerson, Matthew, Munshi, Nikhil, Anderson, Kenneth C., Knoechel, Birgit, Lohr, Jens G.

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Single-cell profiling reveals metabolic reprogramming as a resistance mechanism in BRAF-mutated multiple myeloma gan Waldschmidt, Johannes M., Kloeber, Jake A., Anand, Praveen, Frede, Julia, Kokkalis, Antonis, Dimitrova, Valeriya, Potdar, Sayalee, Nair, Monica S., Vijaykumar, Tushara, Im, Nam Gyu, Guillaumet-Adkins, Amy, Chopra, Nitish, Stuart, Hannah, Budano, Lillian, Sotudeh, Noori, Guo, Guangwu, Grassberger, Clemens, Yee, Andrew J., Laubach, Jacob P., Richardson, Paul G., Anderson, Kenneth C., Raje, Noopur S., Knoechel, Birgit, Lohr, Jens G.

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Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia gan Montanaro, Anna, Kitara, Samuel, Cerretani, Elisa, Marchesini, Matteo, Rompietti, Chiara, Pagliaro, Luca, Gherli, Andrea, Su, Angela, Minchillo, Maria Laura, Caputi, Mariafrancesca, Fioretzaki, Rodanthi, Lorusso, Bruno, Ross, Linda, Alexe, Gabriela, Masselli, Elena, Marozzi, Marina, Rizzi, Federica Maria Angela, La Starza, Roberta, Mecucci, Cristina, Xiong, Yan, Jin, Jian, Falco, Angela, Knoechel, Birgit, Aversa, Franco, Candini, Olivia, Quaini, Federico, Sportoletti, Paolo, Stegmaier, Kimberly, Roti, Giovanni

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Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL gan Anand, Praveen, Guillaumet-Adkins, Amy, Dimitrova, Valeriya, Yun, Huiyoung, Drier, Yotam, Sotudeh, Noori, Rogers, Anna, Ouseph, Madhu M., Nair, Monica, Potdar, Sayalee, Isenhart, Randi, Kloeber, Jake A., Vijaykumar, Tushara, Niu, Leili, Vincent, Tiffaney, Guo, Guangwu, Frede, Julia, Harris, Marian H., Place, Andrew E., Silverman, Lewis B., Teachey, David T., Lane, Andrew A., DeAngelo, Daniel J., Aster, Jon C., Bernstein, Bradley E., Lohr, Jens G., Knoechel, Birgit

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