檢索結果 - Kirkby, Nicholas

Eicosanoids, prostacyclin and cyclooxygenase in the cardiovascular system 由 Mitchell, Jane A, Kirkby, Nicholas S

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Imaging of Tissue-specific and Temporal Activation of GPCR Signaling using DREADD Knock-In Mice 由 Akhmedov, Dmitry, Kirkby, Nicholas S., Mitchell, Jane A., Berdeaux, Rebecca

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Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy 由 Hoefer, Thomas, Armstrong, Paul C., Finsterbusch, Michaela, Chan, Melissa V., Kirkby, Nicholas S., Warner, Timothy D.

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Cardiorenal Tissues Express SARS-CoV-2 Entry Genes and Basigin (BSG/CD147) Increases With Age in Endothelial Cells 由 Ahmetaj-Shala, Blerina, Vaja, Ricky, Atanur, Santosh S., George, Peter M., Kirkby, Nicholas S., Mitchell, Jane A.

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Thrombosis Is Reduced by Inhibition of COX-1, but Unaffected by Inhibition of COX-2, in an Acute Model of Platelet Activation in the Mouse 由 Armstrong, Paul C., Kirkby, Nicholas S., Zain, Zetty N., Emerson, Michael, Mitchell, Jane A., Warner, Timothy D.

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Quantitative 3-Dimensional Imaging of Murine Neointimal and Atherosclerotic Lesions by Optical Projection Tomography 由 Kirkby, Nicholas S., Low, Lucinda, Seckl, Jonathan R., Walker, Brian R., Webb, David J., Hadoke, Patrick W. F.

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Differential role of pannexin-1/ATP/P2X(7) axis in IL-1β release by human monocytes 由 Parzych, Katarzyna, Zetterqvist, Anna V., Wright, William R., Kirkby, Nicholas S., Mitchell, Jane A., Paul-Clark, Mark J.

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COX-2 Protects against Atherosclerosis Independently of Local Vascular Prostacyclin: Identification of COX-2 Associated Pathways Implicate Rgl1 and Lymphocyte Networks 由 Kirkby, Nicholas S., Lundberg, Martina H., Wright, William R., Warner, Timothy D., Paul-Clark, Mark J., Mitchell, Jane A.

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Role of prostacyclin in pulmonary hypertension 由 Mitchell, Jane A., Ahmetaj-Shala, Blerina, Kirkby, Nicholas S., Wright, William R., Mackenzie, Louise S., Reed, Daniel M., Mohamed, Nura

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Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction 由 Armstrong, Paul C. J, Kirkby, Nicholas S., Chan, Melissa V., Finsterbusch, Michaela, Hogg, Nancy, Nourshargh, Sussan, Warner, Timothy D.

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Aspirin inhibits the production of proangiogenic 15(S)-HETE by platelet cyclooxygenase-1 由 Rauzi, Francesca, Kirkby, Nicholas S., Edin, Matthew L., Whiteford, James, Zeldin, Darryl C., Mitchell, Jane A., Warner, Timothy D.

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IN THE PRESENCE OF STRONG P2Y(12) RECEPTOR BLOCKADE, ASPIRIN PROVIDES LITTLE ADDITIONAL INHIBITION OF PLATELET AGGREGATION 由 Armstrong, Paul C.J., Leadbeater, Philip D., Chan, Melissa V., Kirkby, Nicholas S., Jakubowski, Joseph A., Mitchell, Jane A., Warner, Timothy D.

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Blockade of the purinergic P2Y(12) receptor greatly increases the platelet inhibitory actions of nitric oxide 由 Kirkby, Nicholas S., Lundberg, Martina H., Chan, Melissa V., Vojnovic, Ivana, Solomon, Antonia B., Emerson, Michael, Mitchell, Jane A., Warner, Timothy D.

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Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography 由 Kirkby, Nicholas S., Low, Lucinda, Wu, Junxi, Miller, Eileen, Seckl, Jonathan R., Walker, Brian R., Webb, David J., Hadoke, Patrick W. F.

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Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies() 由 Kirkby, Nicholas S., Zaiss, Anne K., Wright, William R., Jiao, Jing, Chan, Melissa V., Warner, Timothy D., R. Herschman, Harvey, Mitchell, Jane A.

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Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis 由 Kirkby, Nicholas S., Tesfai, Abel, Ahmetaj-Shala, Blerina, Gashaw, Hime H., Sampaio, Walkyria, Etelvino, Gisele, Leão, Nádia Miricéia, Santos, Robson A., Mitchell, Jane A.

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Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox 由 Mitchell, Jane A., Shala, Fisnik, Elghazouli, Youssef, Warner, Timothy D., Gaston-Massuet, Carles, Crescente, Marilena, Armstrong, Paul C., Herschman, Harvey R., Kirkby, Nicholas S.

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Selective endothelin A receptor antagonism with sitaxentan reduces neointimal lesion size in a mouse model of intraluminal injury 由 Duthie, Karolina M, Hadoke, Patrick W F, Kirkby, Nicholas S, Miller, Eileen, Ivy, Jessica R, McShane, John F, Lim, Win Gel, Webb, David J

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A bioassay system of autologous human endothelial, smooth muscle cells, and leukocytes for use in drug discovery, phenotyping, and tissue engineering 由 Ahmetaj‐Shala, Blerina, Kawai, Ryota, Marei, Isra, Nikolakopoulou, Zacharoula, Shih, Chih‐Chin, Konain, Bhatti, Reed, Daniel M., Mongey, Róisín, Kirkby, Nicholas S., Mitchell, Jane A.

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Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia 由 d’Emmanuele di Villa Bianca, Roberta, Mitidieri, Emma, Di Minno, Matteo N. D., Kirkby, Nicholas S., Warner, Timothy D., Di Minno, Giovanni, Cirino, Giuseppe, Sorrentino, Raffaella

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