Resultats de la cerca - Khisimuzi Mdluli

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  1. 1
    The Tuberculosis Drug Discovery and Development Pipeline and Emerging Drug Targets

    The Tuberculosis Drug Discovery and Development Pipeline and Emerging Drug Targets per Khisimuzi Mdluli, Takushi Kaneko, Anna M. Upton

    Publicat 2015
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  2. 2
    A novel 3-deoxy-D-manno-octulosonic acid transferase from Chlamydia trachomatis required for expression of the genus-specific epitope.

    A novel 3-deoxy-D-manno-octulosonic acid transferase from Chlamydia trachomatis required for expression of the genus-specific epitope. per Charles Belunis, Khisimuzi Mdluli, Christian R.H. Raetz, Francis E. Nano

    Publicat 1992
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  3. 3
    Ethionamide activation and sensitivity in multidrug-resistant <i>Mycobacterium tuberculosis</i>

    Ethionamide activation and sensitivity in multidrug-resistant <i>Mycobacterium tuberculosis</i> per Andrea E. DeBarber, Khisimuzi Mdluli, M Bosman, Linda‐Gail Bekker, Clifton E. Barry

    Publicat 2000
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  4. 4
    Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant <i>Rv0678</i> Mutant in a Mouse Model of Tuberculosis

    Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant <i>Rv0678</i> Mutant in a Mouse Model of Tuberculosis per Jian Xu, Paul J. Converse, Anna M. Upton, Khisimuzi Mdluli, Nader Fotouhi, Eric L. Nuermberger

    Publicat 2021
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  5. 5
    Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis

    Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis per Rokeya Tasneen, Kathy N. Williams, Opokua Amoabeng, Austin Minkowski, Khisimuzi Mdluli, Anna M. Upton, Eric L. Nuermberger

    Publicat 2014
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  6. 6
    Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis

    Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis per Si-Yang Li, Rokeya Tasneen, Sandeep Tyagi, Heena Soni, Paul J. Converse, Khisimuzi Mdluli, Eric L. Nuermberger

    Publicat 2017
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  7. 7
    Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis

    Sterilizing Activity of Novel TMC207- and PA-824-Containing Regimens in a Murine Model of Tuberculosis per Rokeya Tasneen, Si-Yang Li, Charles A. Peloquin, Dinesh Taylor, Kathy N. Williams, Koen Andries, Khisimuzi Mdluli, Eric L. Nuermberger

    Publicat 2011
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  8. 8
    Biochemical and Genetic Data Suggest that InhA Is Not the Primary Target for Activated Isoniazid in Mycobacterium tuberculosis

    Biochemical and Genetic Data Suggest that InhA Is Not the Primary Target for Activated Isoniazid in Mycobacterium tuberculosis per Khisimuzi Mdluli, David R. Sherman, Mark J. Hickey, Barry N. Kreiswirth, S.M. Morris, C. Kendall Stover, Clifton E. Barry

    Publicat 1996
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  9. 9
    Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model

    Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model per Si‐Yang Li, Paul J. Converse, Fabrice Betoudji, Jin Lee, Khisimuzi Mdluli, Anna M. Upton, Nader Fotouhi, Eric L. Nuermberger

    Publicat 2023
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  10. 10
    Sterilizing Activities of Novel Combinations Lacking First- and Second-Line Drugs in a Murine Model of Tuberculosis

    Sterilizing Activities of Novel Combinations Lacking First- and Second-Line Drugs in a Murine Model of Tuberculosis per Kathy N. Williams, Austin Minkowski, Opokua Amoabeng, Charles A. Peloquin, Dinesh Taylor, Koen Andries, Robert S. Wallis, Khisimuzi Mdluli, Eric L. Nuermberger

    Publicat 2012
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  11. 11
    Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis

    Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis per Ian M. Rosenthal, Rokeya Tasneen, Charles A. Peloquin, Ming Zhang, Deepak V. Almeida, Khisimuzi Mdluli, Petros C. Karakousis, J Grosset, Eric L. Nuermberger

    Publicat 2012
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  12. 12
    Mutations in <i>pepQ</i> Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis

    Mutations in <i>pepQ</i> Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis per Deepak V. Almeida, Thomas R. Ioerger, Sandeep Tyagi, Si-Yang Li, Khisimuzi Mdluli, Koen Andries, J Grosset, J.C. Sacchettini, Eric L. Nuermberger

    Publicat 2016
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  13. 13
    <i>In Vitro</i> and <i>In Vivo</i> Activities of the Nitroimidazole TBA-354 against Mycobacterium tuberculosis

    <i>In Vitro</i> and <i>In Vivo</i> Activities of the Nitroimidazole TBA-354 against Mycobacterium tuberculosis per Anna M. Upton, Sang‐Hyun Cho, Tianjian Yang, Y. Kim, Yong Wang, Yu Lu, B. Wang, Jian Xu, Khisimuzi Mdluli, Zhenkun Ma, Scott G. Franzblau

    Publicat 2014
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  14. 14
    Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis

    Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis per Jian Xu, Si-Yang Li, Deepak V. Almeida, Rokeya Tasneen, Kala Barnes-Boyle, Paul J. Converse, Anna M. Upton, Khisimuzi Mdluli, Nader Fotouhi, Eric L. Nuermberger

    Publicat 2019
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  15. 15
    Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis

    Contribution of Oxazolidinones to the Efficacy of Novel Regimens Containing Bedaquiline and Pretomanid in a Mouse Model of Tuberculosis per Rokeya Tasneen, Fabrice Betoudji, Sandeep Tyagi, Si-Yang Li, Kathy N. Williams, Paul J. Converse, Véronique Dartois, Tian J. Yang, Carl M. Mendel, Khisimuzi Mdluli, Eric L. Nuermberger

    Publicat 2015
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  16. 16
    Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis

    Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis per Scott G. Franzblau, Mary Ann DeGroote, Sang‐Hyun Cho, Koen Andries, Eric L. Nuermberger, Ian M. Orme, Khisimuzi Mdluli, Íñigo Angulo‐Barturen, Thomas Dick, Véronique Dartois, Anne J. Lenaerts

    Publicat 2012
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  17. 17
    Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis

    Bactericidal and sterilizing activity of novel regimens combining bedaquiline or TBAJ-587 with GSK2556286 and TBA-7371 in a mouse model of tuberculosis per Si‐Yang Li, Sandeep Tyagi, Heena Soni, Fabrice Betoudji, Paul J. Converse, Khisimuzi Mdluli, Anna M. Upton, Nader Fotouhi, David Barros-Aguirre, Lluís Ballell, Elena Jiménez‐Navarro, Eric L. Nuermberger

    Publicat 2024
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  18. 18
    Molecular Validation of LpxC as an Antibacterial Drug Target in <i>Pseudomonas aeruginosa</i>

    Molecular Validation of LpxC as an Antibacterial Drug Target in <i>Pseudomonas aeruginosa</i> per Khisimuzi Mdluli, Pamela R. Witte, Toni Kline, Adam W. Barb, Alice L. Erwin, Bryce E. Mansfield, Amanda L. McClerren, Michael C. Pirrung, L. Nathan Tumey, Paul Warrener, Christian R.H. Raetz, C. Kendall Stover

    Publicat 2006
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  19. 19
    GSK2556286 Is a Novel Antitubercular Drug Candidate Effective <i>In Vivo</i> with the Potential To Shorten Tuberculosis Treatment

    GSK2556286 Is a Novel Antitubercular Drug Candidate Effective <i>In Vivo</i> with the Potential To Shorten Tuberculosis Treatment per Eric L. Nuermberger, María Santos Martínez, Olalla Sanz, Beatriz Urones, Jorge Esquivias, Heena Soni, Rokeya Tasneen, Sandeep Tyagi, Si‐Yang Li, Paul J. Converse, Helena I. Boshoff, Gregory T. Robertson, Gurdyal S. Besra, Katherine A. Abrahams, Anna M. Upton, Khisimuzi Mdluli, Gary W. Boyle, Sam Turner, Nader Fotouhi, N. Cammack, Juan Miguel Siles, Marta Alonso, Jaime Escribano, Joël Lelièvre, Joaquin Rullas-Trincado, Esther Pérez‐Herrán, Robert H. Bates, Gareth Maher-Edwards, David Barros, Lluís Ballell, Elena Jiménez

    Publicat 2022
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  20. 20
    Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

    Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens per Nicholas D. Walter, Sarah E. M. Born, Gregory T. Robertson, Matthew J. Reichlen, Christian Dide-Agossou, Victoria Ektnitphong, Karen Rossmassler, Michelle E. Ramey, Allison Bauman, Victor Ozols, Shelby C. Bearrows, Gary K. Schoolnik, Gregory Dolganov, Benjamin J. Garcia, Emmanuel Musisi, William Worodria, Laurence Huang, J. Lucian Davis, Nguyen Viet Nhung, Hung Van Nguyen, Nguyễn Thị Vân Anh, Ha Phan, Carol J. Wilusz, Brendan K. Podell, N Sanoussi, Bouke C. de Jong, Corinne Merle, Dissou Affolabi, Helen McIlleron, Maria Garcia‐Cremades, Ekaterina Maidji, Franceen Eshun‐Wilson, Brandon Aguilar-Rodriguez, Dhuvarakesh Karthikeyan, Khisimuzi Mdluli, Cathy Bansbach, Anne J. Lenaerts, Radojka M. Savić, Payam Nahid, Joshua Vasquez, Martin I. Voskuil

    Publicat 2021
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