Ngā hua rapu - Kevin Shee
- E whakaatu ana i te 1 - 10 hua o te 10
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Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy mā Kevin Shee, Jason D. Wells, Amanda Jiang, Todd W. Miller
I whakaputaina 2019Artigo -
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Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer mā Riley A. Hampsch, Kevin Shee, Darcy Bates, Lionel D. Lewis, Laurent Désiré, Bertrand Leblond, Eugene Demidenko, Kurtis Stefan, Yina H. Huang, Todd W. Miller
I whakaputaina 2017Artigo -
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P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer mā Lloye M. Dillon, Jennifer R. Bean, Wei Yang, Kevin Shee, Lynn Symonds, Justin M. Balko, W. Hayes McDonald, S. Liu, Ana M. González-Angulo, Gordon B. Mills, Carlos L. Arteaga, Todd W. Miller
I whakaputaina 2014Artigo -
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Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer mā Kevin Shee, Wei Yang, John W. Hinds, Riley A. Hampsch, Frederick S. Varn, Nicole A. Traphagen, Kishan Patel, Chao Cheng, Nicole P. Jenkins, Arminja N. Kettenbach, Eugene Demidenko, Philip Owens, Anthony C. Faber, Todd R. Golub, Ravid Straussman, Todd W. Miller
I whakaputaina 2018Artigo -
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AMPK Activation by Metformin Promotes Survival of Dormant ER+ Breast Cancer Cells mā Riley A. Hampsch, Jason D. Wells, Nicole A. Traphagen, Charlotte F. McCleery, Jennifer Fields, Kevin Shee, Lloye M. Dillon, Darcy B. Pooler, Lionel D. Lewis, Eugene Demidenko, Yina H. Huang, Jonathan D. Marotti, Abigail E. Goen, William B. Kinlaw, Todd W. Miller
I whakaputaina 2020Artigo -
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Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion mā Ravid Straussman, Teppei Morikawa, Kevin Shee, Michal Barzily-Rokni, Zhi Rong Qian, Jinyan Du, Ashli Davis, Margaret Mongare, Joshua Gould, Dennie T. Frederick, Zachary A. Cooper, Paul B. Chapman, David B. Solit, Antoni Ribas, Roger S. Lo, Keith T. Flaherty, Shuji Ogino, Jennifer A. Wargo, Todd R. Golub
I whakaputaina 2012Artigo -
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The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to transcriptionally active wildtype p53 mā Esha Madan, Taylor M. Parker, Matthias R. Bauer, Alisha Dhiman, Christopher J. Pelham, Masaki Nagane, M. Lakshmi Kuppusamy, Matti Holmes, Thomas R. Holmes, Kranti Shaik, Kevin Shee, Salome Kiparoidze, Sean D. Smith, Yu-Soon A. Park, Jennifer J. Gomm, J. Louise Jones, Ana Raquel Tomás, Ana C. Cunha, Karuppaiyah Selvendiran, Laura A. Hansen, Alan R. Fersht, Kálmán Hideg, Rajan Gogna, Periannan Kuppusamy
I whakaputaina 2018Artigo -
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Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer mā Margaret L. Axelrod, Mellissa J. Nixon, Paula I. González-Ericsson, Riley E. Bergman, Mark A. Pilkinton, Wyatt J. McDonnell, Violeta Sánchez, Susan R. Opalenik, Sherene Loi, Jing Zhou, Sean Mackay, Brent N. Rexer, Vandana G. Abramson, Valerie M. Jansen, S. Mallal, Joshua Donaldson, Sara M. Tolaney, Ian E. Krop, Ana C. Garrido-Castro, Jonathan D. Marotti, Kevin Shee, Todd W. Miller, Melinda E. Sanders, Ingrid A. Mayer, Roberto Salgado, Justin M. Balko
I whakaputaina 2020Artigo -
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Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine mā Leore T. Geller, Michal Barzily-Rokni, Tal Danino, Oliver Jonas, Noam Shental, Deborah Nejman, Nancy Gavert, Yaara Zwang, Zachary A. Cooper, Kevin Shee, Christoph A. Thaiss, Alexandre Reuben, Jonathan Livny, Roi Avraham, Dennie T. Frederick, Matteo Ligorio, Kelly Chatman, Stephen Johnston, Carrie M. Mosher, Alexander Brandis, Garold Fuks, Candice R. Gurbatri, Vancheswaran Gopalakrishnan, Michael P. Kim, Mark W. Hurd, Matthew H. G. Katz, Jason B. Fleming, Anirban Maitra, David A. Smith, Matt Skalak, Jeffrey Bu, Monia Michaud, Sunia A. Trauger, Iris Barshack, Talia Golan, Judith Sandbank, Keith T. Flaherty, Anna Mandinova, Wendy S. Garrett, Sarah P. Thayer, Cristina R. Ferrone, Curtis Huttenhower, Sangeeta N. Bhatia, Dirk Gevers, Jennifer A. Wargo, Todd R. Golub, Ravid Straussman
I whakaputaina 2017Artigo
Ngā utauta rapu:
Ngā marau whai pānga
Biology
Cancer research
Cancer
Internal medicine
Medicine
Breast cancer
Cell biology
Genetics
PI3K/AKT/mTOR pathway
Signal transduction
Biochemistry
Drug resistance
Gene
Kinase
MAPK/ERK pathway
Microbiology
Pharmacology
Protein kinase B
Chemistry
Chemotherapy
Drug
Endocrinology
Gene expression
Oncology
Receptor
mTORC1
AMPK
Apoptosis
Bacteria
Biomarker