Search Results - Kevin Myant

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  1. 1
    LSH Cooperates with DNA Methyltransferases To Repress Transcription

    LSH Cooperates with DNA Methyltransferases To Repress Transcription by Kevin Myant, Irina Stancheva

    Published 2007
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  2. 2
    SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells

    SNF2 family ATPase LSH promotes phosphorylation of H2AX and efficient repair of DNA double-strand breaks in mammalian cells by Joe Burrage, Ausma Termanis, Andreas Geissner, Kevin Myant, Katrina Gordon, Irina Stancheva

    Published 2012
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  3. 3
    Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates <i>Apc1</i>-driven intestinal stem cell hyperplasia in the <i>Drosophila</i> adult midgut

    Non-autonomous crosstalk between the Jak/Stat and Egfr pathways mediates <i>Apc1</i>-driven intestinal stem cell hyperplasia in the <i>Drosophila</i> adult midgut by Julia B. Cordero, Rhoda Stefanatos, Kevin Myant, Marcos Vidal, Owen J. Sansom

    Published 2012
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  4. 4
    Targeting of De Novo DNA Methylation Throughout the Oct-4 Gene Regulatory Region in Differentiating Embryonic Stem Cells

    Targeting of De Novo DNA Methylation Throughout the Oct-4 Gene Regulatory Region in Differentiating Embryonic Stem Cells by Rodoniki Athanasiadou, Dina De Sousa, Kevin Myant, Cara Merusi, Irina Stancheva, Adrian Bird

    Published 2010
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  5. 5
    Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression

    Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression by Simon A. Woodcock, Helen Rushton, Eduardo Castañeda-Saucedo, Kevin Myant, Gavin White, Karen Blyth, Owen J. Sansom, Angeliki Malliri

    Published 2010
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  6. 6
    LSH and G9a/GLP complex are required for developmentally programmed DNA methylation

    LSH and G9a/GLP complex are required for developmentally programmed DNA methylation by Kevin Myant, Ausma Termanis, Arvind Y. M. Sundaram, Tristin Boe, Chao Li, Cara Merusi, Joe Burrage, Jose I. de las Heras, Irina Stancheva

    Published 2010
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  7. 7
    Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss

    Cyclin D2–Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss by Alicia M. Cole, Kevin Myant, Karen R. Reed, Rachel A. Ridgway, Dimitris Athineos, Gijs R. van den Brink, Vanesa Muncan, Hans Clevers, Alan R. Clarke, Peter Sicinski, Owen J. Sansom

    Published 2010
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  8. 8
    Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

    Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo by Toby J. Phesse, Kevin Myant, Alicia M. Cole, Rachel A. Ridgway, Helen Pearson, Vanesa Muncan, Gijs R. van den Brink, Karen H. Vousden, Rosalie C. Sears, Lyubomir T. Vassilev, Alan R. Clarke, Owen J. Sansom

    Published 2014
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  9. 9
    Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation

    Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation by Kevin Myant, Xi Qiao, Tuuli Halonen, Christophé Côme, Anni Laine, Mahnaz Janghorban, Johanna I. Partanen, John W. Cassidy, Erinn‐Lee Ogg, Patrizia Cammareri, Tiina Laiterä, Juha Okkeri, Juha Klefström, Rosalie C. Sears, Owen J. Sansom, Jukka Westermarck

    Published 2015
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  10. 10
    Tumor cell‐specific inhibition of <scp>MYC</scp> function using small molecule inhibitors of the <scp>HUWE</scp>1 ubiquitin ligase

    Tumor cell‐specific inhibition of <scp>MYC</scp> function using small molecule inhibitors of the <scp>HUWE</scp>1 ubiquitin ligase by Stefanie Peter, Jennyfer Bultinck, Kevin Myant, Laura A. Jaenicke, Susanne Walz, Judith M. Müller, Michael Gmachl, Matthias Treu, Guido Boehmelt, Carsten P. Ade, Werner Schmitz, Armin Wiegering, Christoph Otto, Nikita Popov, Owen J. Sansom, Norbert Kraut, Martin Eilers

    Published 2014
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  11. 11
    <i> <scp>HUWE</scp> 1 </i> is a critical colonic tumour suppressor gene that prevents <scp>MYC</scp> signalling, <scp>DNA</scp> damage accumulation and tumour initiation

    <i> <scp>HUWE</scp> 1 </i> is a critical colonic tumour suppressor gene that prevents <scp>MYC</scp> signalling, <scp>DNA</scp> damage accumulation and tumour initiation by Kevin Myant, Patrizia Cammareri, Michael C. Hodder, Jimi Wills, Alex von Kriegsheim, Balázs Győrffy, Mamun Rashid, Simona Polo, Elena Maspero, Lynsey Vaughan, Basanta Gurung, Evan Barry, Angeliki Malliri, Fernando D. Camargo, David J. Adams, Antonio Iavarone, Anna Lasorella, Owen J. Sansom

    Published 2016
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  12. 12
    ROS Production and NF-κB Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation

    ROS Production and NF-κB Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation by Kevin Myant, Patrizia Cammareri, Ewan J. McGhee, Rachel A. Ridgway, David J. Huels, Julia B. Cordero, Sarah Schwitalla, Gabriela Kalna, Erinn-Lee Ogg, Dimitris Athineos, Paul Timpson, Marcos Vidal, Graeme I. Murray, Florian R. Greten, Kurt I. Anderson, Owen J. Sansom

    Published 2013
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  13. 13
    RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer

    RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer by Adam E. Hall, Sebastian Pohl, Patrizia Cammareri, Stuart Aitken, Nicholas T. Younger, Michela Raponi, Caroline V. Billard, Alfonso Bolado‐Carrancio, Aslihan Bastem, Paz Freile, Fiona Haward, Ian R. Adams, Javier F. Cáceres, Paula Preyzner, Alex von Kriegsheim, Malcolm G. Dunlop, Farhat Din, Kevin Myant

    Published 2022
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  14. 14
    The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues

    The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues by Anna‐Karin Johnsson, Yanfeng Dai, Max Nobis, Martin J. Baker, Ewan J. McGhee, Simon Walker, Juliane P. Schwarz, Shereen Kadir, Jennifer P. Morton, Kevin Myant, David J. Huels, Anne Segonds-Pichon, Owen J. Sansom, Kurt I. Anderson, Paul Timpson, Heidi C. E. Welch

    Published 2014
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  15. 15
    The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

    The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers by Javier Muñoz, Daniel E. Stange, Arnout Schepers, Marc van de Wetering, Bon‐Kyoung Koo, Shalev Itzkovitz, Richard Volckmann, Kevin S. Kung, Jan Köster, Sorina Radulescu, Kevin Myant, Rogier Versteeg, Owen J. Sansom, Johan H. van Es, Nick Barker, Alexander van Oudenaarden, Shabaz Mohammed, Albert J. R. Heck, Hans Clevers

    Published 2012
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  16. 16
    Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling

    Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc Signaling by G H S Ashton, Jennifer P. Morton, Kevin Myant, Toby J. Phesse, Rachel A. Ridgway, Victoria Marsh, Julie A. Wilkins, Dimitris Athineos, Vanesa Muncan, Richard Kemp, Kristi L. Neufeld, Hans Clevers, Valerie G. Brunton, Douglas J. Winton, Xiaoyan Wang, Rosalie C. Sears, Alan R. Clarke, Margaret C. Frame, Owen J. Sansom

    Published 2010
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  17. 17
    mTORC1-mediated translational elongation limits intestinal tumour initiation and growth

    mTORC1-mediated translational elongation limits intestinal tumour initiation and growth by William J. Faller, Thomas J. Jackson, John R. P. Knight, Rachel A. Ridgway, Thomas Jamieson, Saadia A. Karim, Carolyn Jones, Sorina Radulescu, David J. Huels, Kevin Myant, Kate Dudek, Helen A. Casey, Alessandro Scopelliti, Julia B. Cordero, Marcos Vidal, Mario Pende, Alexey G. Ryazanov, Nahum Sonenberg, Oded Meyuhas, Michael N. Hall, Martin Bushell, Anne E. Willis, Owen J. Sansom

    Published 2014
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