Search Results - Kazuhiro Irie

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  1. 1
    New diagnostic method for Alzheimer’s disease based on the toxic conformation theory of amyloid β

    New diagnostic method for Alzheimer’s disease based on the toxic conformation theory of amyloid β by Kazuhiro Irie

    Published 2019
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  2. 2
    Inhibitory Activities of Antioxidant Flavonoids from <i>Tamarix gallica</i> on Amyloid Aggregation Related to Alzheimer’s and Type 2 Diabetes Diseases

    Inhibitory Activities of Antioxidant Flavonoids from <i>Tamarix gallica</i> on Amyloid Aggregation Related to Alzheimer’s and Type 2 Diabetes Diseases by Asma Ben Hmidene, Mizuho Hanaki, Kazuma Murakami, Kazuhiro Irie, Hiroko Isoda, Hideyuki Shigemori

    Published 2017
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  3. 3
    Neurotoxicity and Physicochemical Properties of Aβ Mutant Peptides from Cerebral Amyloid Angiopathy

    Neurotoxicity and Physicochemical Properties of Aβ Mutant Peptides from Cerebral Amyloid Angiopathy by Kazuma Murakami, Kazuhiro Irie, Akira Morimoto, Hajime Ohigashi, Mayumi Shindo, Masaya Nagao, Takahiko Shimizu, Takuji Shirasawa

    Published 2003
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  4. 4
    Analysis of the Secondary Structure of β-Amyloid (Aβ42) Fibrils by Systematic Proline Replacement

    Analysis of the Secondary Structure of β-Amyloid (Aβ42) Fibrils by Systematic Proline Replacement by Akira Morimoto, Kazuhiro Irie, Kazuma Murakami, Yuichi Masuda, Hajime Ohigashi, Masaya Nagao, Hiroyuki Fukuda, Takahiko Shimizu, Takuji Shirasawa

    Published 2004
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  5. 5
    Site-specific Inhibitory Mechanism for Amyloid β42 Aggregation by Catechol-type Flavonoids Targeting the Lys Residues

    Site-specific Inhibitory Mechanism for Amyloid β42 Aggregation by Catechol-type Flavonoids Targeting the Lys Residues by Mizuho Sato, Kazuma Murakami, Mayumi Uno, Yu Nakagawa, Sumie Katayama, Ken‐ichi Akagi, Yuichi Masuda, K. Takegoshi, Kazuhiro Irie

    Published 2013
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  6. 6
    A New Lyngbyatoxin from the Hawaiian Cyanobacterium Moorea producens

    A New Lyngbyatoxin from the Hawaiian Cyanobacterium Moorea producens by Weina Jiang, Wei Zhou, Hajime Uchida, Masayuki Kikumori, Kazuhiro Irie, Ryuichi Watanabe, Toshiyuki Suzuki, Bryan Sakamoto, Michiya Kamio, Hiroshi Nagai

    Published 2014
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  7. 7
    Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model

    Insulin deficiency promotes formation of toxic amyloid-β42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model by Tomohiro Imamura, Yuki Yanagihara, Yasumasa Ohyagi, Norimichi Nakamura, Kyoko Iinuma, Ryo Yamasaki, Hirohide Asai, Masahiro Maeda, Kazuma Murakami, Kazuhiro Irie, Jun‐ichi Kira

    Published 2020
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  8. 8
    Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis)

    Isolation, identification, and biological evaluation of Nrf2-ARE activator from the leaves of green perilla (Perilla frutescens var. crispa f. viridis) by Yasuhiko Izumi, Atsuko Matsumura, Seiko Wakita, Ken‐ichi Akagi, Hiroyuki Fukuda, Toshiaki Kume, Kazuhiro Irie, Yuki Takada‐Takatori, Hachiro Sugimoto, Tadashi Hashimoto, Akinori Akaike

    Published 2012
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  9. 9
    SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease

    SOD1 (Copper/Zinc Superoxide Dismutase) Deficiency Drives Amyloid β Protein Oligomerization and Memory Loss in Mouse Model of Alzheimer Disease by Kazuma Murakami, Nakaba Murata, Yoshihiro Noda, Shoichi Tahara, Takao Kaneko, Noriaki Kinoshita, Hiroyuki Hatsuta, Shigeo Murayama, Kevin J. Barnham, Kazuhiro Irie, Takuji Shirasawa, Takahiko Shimizu

    Published 2011
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  10. 10
    Stomatal Density is Controlled by a Mesophyll-Derived Signaling Molecule

    Stomatal Density is Controlled by a Mesophyll-Derived Signaling Molecule by Tatsuhiko Kondo, Ryoko Kajita, Aya Miyazaki, Mayumi Hokoyama, Touko Nakamura-Miura, Satoko Mizuno, Yuichi Masuda, Kazuhiro Irie, Yuki Tanaka, Shinobu Takada, Tatsuo Kakimoto, Youji Sakagami

    Published 2009
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  11. 11
    Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer’s disease diagnosis

    Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer’s disease diagnosis by Kazuma Murakami, Maki Tokuda, Takashi Suzuki, Yumi Irie, Mizuho Hanaki, Naotaka Izuo, Yoko Monobe, Ken‐ichi Akagi, Ryotaro Ishii, Harutsugu Tatebe, Takahiko Tokuda, Masahiro Maeda, Toshiaki Kume, Takahiko Shimizu, Kazuhiro Irie

    Published 2016
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  12. 12
    Intracellular Accumulation of Toxic Turn Amyloid-β is Associated with Endoplasmic Reticulum Stress in Alzheimer's Disease

    Intracellular Accumulation of Toxic Turn Amyloid-β is Associated with Endoplasmic Reticulum Stress in Alzheimer's Disease by Naoko Soejima, Yasumasa Ohyagi, Norimichi Nakamura, Eri Himeno, Kyoko Iinuma, Nobutaka Sakae, Ryo Yamasaki, Takeshi Tabira, Kazuma Murakami, Kazuhiro Irie, Noriaki Kinoshita, Frank M. LaFerla, Yutaka Kiyohara, Toru Iwaki, Jun‐ichi Kira

    Published 2013
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  13. 13
    Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

    Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones by Kento Tsukada, Shono Shinki, Akiho Kaneko, Kazuma Murakami, Kazuhiro Irie, Masatoshi Murai, Hideto Miyoshi, Shingo Dan, Kumi Kawaji, Hironori Hayashi, Eiichi Kodama, Aki Hori, Emil Salim, Takayuki Kuraishi, Naoya Hirata, Yasunari Kanda, Teigo Asai

    Published 2020
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  14. 14
    Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation

    Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation by Luka Kulic, Jordan McAfoose, Tobias Welt, Christian Tackenberg, Claudia Späni, Fabian Wirth, Verena H. Finder, Uwe Konietzko, M. Hunter Giese, Anne Eckert, K Noriaki, Takahiko Shimizu, Kazuma Murakami, Kazuhiro Irie, Suhail Rasool, Charles Glabe, C. Hock, Roger M. Nitsch

    Published 2012
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  15. 15
    Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

    Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness by Takayuki Kondo, Masashi Asai, Kayoko Tsukita, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Keiko Imamura, Naohiro Egawa, Naoki Yahata, Keisuke Okita, Kazutoshi Takahashi, Isao Asaka, Takashi Aoi, Akira Watanabe, Kaori Watanabe, Chie Kadoya, Rie Nakano, Dai Watanabe, Kei Maruyama, Osamu Hori, Satoshi Hibino, Tominari Choshi, Tatsutoshi Nakahata, Hiroyuki Hioki, Takeshi Kaneko, Motoko Naitoh, Katsuhiro Yoshikawa, Satoko Yamawaki, Shigehiko Suzuki, Ryuji Hata, Shu-ichi Ueno, Tsuneyoshi Seki, Kazuhiro Kobayashi, Tatsushi Toda, Kazuma Murakami, Kazuhiro Irie, William L. Klein, Hiroshi Mori, Takashi Asada, Ryōsuke Takahashi, Nobuhisa Iwata, Shinya Yamanaka, Haruhisa Inoue

    Published 2013
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