Результаты поиска - Kazantsev, Aleksey

Drug Targeting of α-Synuclein Oligomerization in Synucleinopathies по Outeiro, Tiago Fleming, Kazantsev, Aleksey

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Drug Targeting of Dysregulated Transcription in Huntington’s Disease по Kazantsev, Aleksey G., Hersch, Steven M.

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Reply to Valenza and Cattaneo: SIRT2-mediated neuroprotection and cholesterol dyshomeostasis in Huntington’s disease по Luthi-Carter, Ruth, Kazantsev, Aleksey G.

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Editorial on Special Topic: Sirtuins in Metabolism, Aging, and Disease по Kazantsev, Aleksey G., Outeiro, Tiago F.

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The role of Nrf2 signaling in counteracting neurodegenerative diseases по Dinkova‐Kostova, Albena T., Kostov, Rumen V., Kazantsev, Aleksey G.

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3-(N-Arylsulfamoyl)benzamides, Inhibitors of Human Sirtuin Type 2 (SIRT2) по Choi, Soo Hyuk, Quinti, Luisa, Kazantsev, Aleksey G., Silverman, Richard B.

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RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells по Maxwell, Michele M., Pasinelli, Piera, Kazantsev, Aleksey G., Brown, Robert H.

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SIRT2 as a Therapeutic Target for Age-Related Disorders по de Oliveira, Rita Machado, Sarkander, Jana, Kazantsev, Aleksey G., Outeiro, Tiago Fleming

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Design and Evaluation of 3-(Benzylthio)benzamide Derivatives as Potent and Selective SIRT2 Inhibitors по Khanfar, Mohammad A., Quinti, Luisa, Wang, Hua, Nobles, Johnathan, Kazantsev, Aleksey G., Silverman, Richard B.

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Development and Characterization of 3-(Benzylsulfonamido)benzamides as Potent and Selective SIRT2 Inhibitors по Khanfar, Mohammad A., Quinti, Luisa, Wang, Hua, Choi, Soo Hyuk, Kazantsev, Aleksey G., Silverman, Richard B.

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Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia по Spires-Jones, Tara L., Fox, Leora M., Rozkalne, Anete, Pitstick, Rose, Carlson, George A., Kazantsev, Aleksey G.

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LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington’s Disease по Chopra, Vanita, Quinti, Luisa, Khanna, Prarthana, Paganetti, Paolo, Kuhn, Rainer, Young, Anne B., Kazantsev, Aleksey G., Hersch, Steven

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Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease по Lecerf, Jean-Michel, Shirley, Thomas L., Zhu, Quan, Kazantsev, Aleksey, Amersdorfer, Peter, Housman, David E., Messer, Anne, Huston, James S.

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Sirtuins in Alzheimer’s Disease: SIRT2-Related GenoPhenotypes and Implications for PharmacoEpiGenetics по Cacabelos, Ramón, Carril, Juan C., Cacabelos, Natalia, Kazantsev, Aleksey G., Vostrov, Alex V., Corzo, Lola, Cacabelos, Pablo, Goldgaber, Dmitry

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A small-molecule therapeutic lead for Huntington's disease: Preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse по Chopra, Vanita, Fox, Jonathan H., Lieberman, Greg, Dorsey, Kathryn, Matson, Wayne, Waldmeier, Peter, Housman, David E., Kazantsev, Aleksey, Young, Anne B., Hersch, Steven

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The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS по Maxwell, Michele M., Tomkinson, Elizabeth M., Nobles, Johnathan, Wizeman, John W., Amore, Allison M., Quinti, Luisa, Chopra, Vanita, Hersch, Steven M., Kazantsev, Aleksey G.

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription по Steffan, Joan S., Kazantsev, Aleksey, Spasic-Boskovic, Olivera, Greenwald, Marilee, Zhu, Ya-Zhen, Gohler, Heike, Wanker, Erich E., Bates, Gillian P., Housman, David E., Thompson, Leslie M.

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Pharmacological promotion of inclusion formation: A therapeutic approach for Huntington’s and Parkinson’s diseases по Bodner, Ruth A., Outeiro, Tiago Fleming, Altmann, Stephen, Maxwell, Michele M., Cho, Stephanie H., Hyman, Bradley T., McLean, Pamela J., Young, Anne B., Housman, David E., Kazantsev, Aleksey G.

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Evaluation of Histone Deacetylases as Drug Targets in Huntington’s Disease models: Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients... по Quinti, Luisa, Chopra, Vanita, Rotili, Dante, Valente, Sergio, Amore, Allison, Franci, Gianluigi, Meade, Sarah, Valenza, Marta, Altucci, Lucia, Maxwell, Michele M., Cattaneo, Elena, Hersch, Steven, Mai, Antonello, Kazantsev, Aleksey

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The Sirtuin 2 Inhibitor AK-7 is Neuroprotective in Huntington Disease Mouse Models по Chopra, Vanita, Quinti, Luisa, Kim, Jinho, Vollor, Lorraine, Kumaraswamy, Lakshminarayanan, Edgerly, Christina, Cipicchio, Patricia M., Lauver, Molly A., Choi, Soo Hyuk, Silverman, Richard B., Ferrante, Robert J., Hersch, Steven, Kazantsev, Aleksey G.

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