Resultats de la cerca - Kavya Ramkumar

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  1. 1
    Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors

    Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors per Erik Serrao, Srinivas Odde, Kavya Ramkumar, Nouri Neamati

    Publicat 2009
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  2. 2
    The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress–Mediated Apoptosis in Pancreatic Cancer

    The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress–Mediated Apoptosis in Pancreatic Cancer per Soma Samanta, Suhui Yang, Bikash Debnath, Ding Xue, Yuting Kuang, Kavya Ramkumar, Amy S. Lee, Mats Ljungman, Nouri Neamati

    Publicat 2021
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  3. 3
    A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers

    A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers per Bingnan Zhang, Kavya Ramkumar, Robert J. Cardnell, Carl M. Gay, C. Allison Stewart, Wei‐Lien Wang, Junya Fujimoto, Ignacio I. Wistuba, Lauren A. Byers

    Publicat 2021
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  4. 4
    Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor

    Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor per Kavya Ramkumar, Soma Samanta, Anahita Kyani, Suhui Yang, Shuzo Tamura, Elizabeth K. Ziemke, Jeanne A. Stuckey, Si Li, Krishnapriya Chinnaswamy, Hiroyuki Otake, Bikash Debnath, V. N. Yarovenko, Judith S. Sebolt‐Leopold, Mats Ljungman, Nouri Neamati

    Publicat 2016
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  5. 5
    Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer

    Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer per Kasey R. Cargill, C. Allison Stewart, Elizabeth M. Park, Kavya Ramkumar, Carl M. Gay, Robert J. Cardnell, Qi Wang, Lixia Diao, Li Shen, You-Hong Fan, Wai Kin Chan, Philip L. Lorenzi, Trudy G. Oliver, Jing Wang, Lauren A. Byers

    Publicat 2021
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  6. 6
    Combination Treatment of the Oral CHK1 Inhibitor, SRA737, and Low-Dose Gemcitabine Enhances the Effect of Programmed Death Ligand 1 Blockade by Modulating the Immune Microenvironment in SCLC

    Combination Treatment of the Oral CHK1 Inhibitor, SRA737, and Low-Dose Gemcitabine Enhances the Effect of Programmed Death Ligand 1 Blockade by Modulating the Immune Microenvironme... per Triparna Sen, Carminia Maria Della Corte, Snezana Milutinovic, Robert J. Cardnell, Lixia Diao, Kavya Ramkumar, Carl M. Gay, C. Allison Stewart, You-Hong Fan, Li Shen, Ryan J. Hansen, Bryan Strouse, Michael P. Hedrick, Christian A. Hassig, John V. Heymach, Jing Wang, Lauren A. Byers

    Publicat 2019
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  7. 7
    AXL Inhibition Induces DNA Damage and Replication Stress in Non–Small Cell Lung Cancer Cells and Promotes Sensitivity to ATR Inhibitors

    AXL Inhibition Induces DNA Damage and Replication Stress in Non–Small Cell Lung Cancer Cells and Promotes Sensitivity to ATR Inhibitors per Kavya Ramkumar, C. Allison Stewart, Kasey R. Cargill, Carminia Maria Della Corte, Qi Wang, Li Shen, Lixia Diao, Robert J. Cardnell, David H. Peng, B. Leticia Rodriguez, You-Hong Fan, John V. Heymach, Jing Wang, Carl M. Gay, Don L. Gibbons, Lauren A. Byers

    Publicat 2020
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  8. 8
    DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer

    DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer per Benjamin B. Morris, Simon Heeke, Yuanxin Xi, Lixia Diao, Qi Wang, Pedro Rocha, Edurne Arriola, Myung Chang Lee, Darren R. Tyson, Kyle Concannon, Kavya Ramkumar, C. Allison Stewart, Robert J. Cardnell, Runsheng Wang, Vito Quaranta, Jing Wang, John V. Heymach, Barzin Y. Nabet, David S. Shames, Carl M. Gay, Lauren A. Byers

    Publicat 2025
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  9. 9
    STING Pathway Expression Identifies NSCLC With an Immune-Responsive Phenotype

    STING Pathway Expression Identifies NSCLC With an Immune-Responsive Phenotype per Carminia Maria Della Corte, Triparna Sen, Carl M. Gay, Kavya Ramkumar, Lixia Diao, Robert J. Cardnell, B. Leticia Rodriguez, C. Allison Stewart, Vassiliki A. Papadimitrakopoulou, Laura Gibson, Jared J. Fradette, Qi Wang, You-Hong Fan, David H. Peng, Marcelo V. Negrão, Ignacio I. Wistuba, Junya Fujimoto, Luisa M. Solis Soto, Carmen Behrens, Ferdinandos Skoulidis, John V. Heymach, Jing Wang, Don L. Gibbons, Lauren A. Byers

    Publicat 2020
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  10. 10
    Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2–Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology

    Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2–Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology per C. Allison Stewart, Carl M. Gay, Kavya Ramkumar, Kasey R. Cargill, Robert J. Cardnell, Monique B. Nilsson, Simon Heeke, Elizabeth M. Park, Samrat T. Kundu, Lixia Diao, Qi Wang, Li Shen, Yuanxin Xi, Bingnan Zhang, Carminia Maria Della Corte, You-Hong Fan, Kiran Kundu, Boning Gao, Kimberley Avila, Curtis R. Pickering, Faye M. Johnson, Jianjun Zhang, Humam Kadara, John D. Minna, Don L. Gibbons, Jing Wang, John V. Heymach, Lauren A. Byers

    Publicat 2021
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  11. 11
    Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities

    Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities per Carl M. Gay, C. Allison Stewart, Elizabeth M. Park, Lixia Diao, Sarah M. Groves, Simon Heeke, Barzin Y. Nabet, Junya Fujimoto, Luisa M. Solis, Wei Lü, Yuanxin Xi, Robert J. Cardnell, Qi Wang, Giulia Fabbri, Kasey R. Cargill, Natalie I. Vokes, Kavya Ramkumar, Bingnan Zhang, Carminia Maria Della Corte, Paul Robson, Stephen G. Swisher, Jack A. Roth, Bonnie S. Glisson, David S. Shames, Ignacio I. Wistuba, Jing Wang, Vito Quaranta, John D. Minna, John V. Heymach, Lauren A. Byers

    Publicat 2021
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