Search Results - Katrin Sproesser

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  1. 1
    The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression When Combined with Docetaxel

    The Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase Inhibitor AZD6244 (ARRY-142886) Induces Growth Arrest in Melanoma Cells and Tumor Regression When Combine... by Nikolas K. Haass, Katrin Sproesser, Thiennga K. Nguyen, Rooha Contractor, Calvo Medina, Katherine L. Nathanson, Meenhard Herlyn, Keiran S.M. Smalley

    Published 2008
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  2. 2
    PLX4032, a potent inhibitor of the B‐Raf V600E oncogene, selectively inhibits V600E‐positive melanomas

    PLX4032, a potent inhibitor of the B‐Raf V600E oncogene, selectively inhibits V600E‐positive melanomas by John Tayu Lee, Ling Li, Patricia Brafford, Marcia van den Eijnden, Molly B. Halloran, Katrin Sproesser, Nikolas K. Haass, Keiran S.M. Smalley, James Tsai, Gideon Bollag, Meenhard Herlyn

    Published 2010
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  3. 3
    Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance

    Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance by Sydney M. Shaffer, Margaret C. Dunagin, Stefan Torborg, Eduardo A. Torre, Benjamin Emert, Clemens Krepler, Marilda Beqiri, Katrin Sproesser, Patricia Brafford, Min Xiao, Elliott Eggan, Ioannis N. Anastopoulos, Cesar A. Vargas-García, Abhyudai Singh, Katherine L. Nathanson, Meenhard Herlyn, Arjun Raj

    Published 2017
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  4. 4
    A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia

    A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia by Priyanka Nair-Gupta, Michael Diem, Dara Reeves, Weirong Wang, Robert Schulingkamp, Katrin Sproesser, Bethany Mattson, Bradley Heidrich, Mark Mendonça, Jocelin Joseph, Jocelyn Sendecki, Brad Foulk, Gerald Chu, Damien Fink, Qun Jiao, Sheng‐Jiun Wu, Kathryn Packman, Yusri Elsayed, Ricardo M. Attar, François Gaudet

    Published 2020
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  5. 5
    Oncogenic BRAF-Mediated Melanoma Cell Invasion

    Oncogenic BRAF-Mediated Melanoma Cell Invasion by Hezhe Lu, Shujing Liu, Gao Zhang, Lawrence N. Kwong, Yueyao Zhu, John P. Miller, Yi Hu, Wenqun Zhong, Jingwen Zeng, Lawrence W. Wu, Clemens Krepler, Katrin Sproesser, Min Xiao, Wei Xu, Giorgos C. Karakousis, Lynn M. Schuchter, Jeffery Field, Paul J. Zhang, Meenhard Herlyn, Xiaowei Xu, Wei Guo

    Published 2016
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  6. 6
    Personalized Preclinical Trials in BRAF Inhibitor–Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies

    Personalized Preclinical Trials in BRAF Inhibitor–Resistant Patient-Derived Xenograft Models Identify Second-Line Combination Therapies by Clemens Krepler, Min Xiao, Katrin Sproesser, Patricia Brafford, Batool Shannan, Marilda Beqiri, Qin Liu, Wei Xu, Bradley Garman, Katherine L. Nathanson, Xiaowei Xu, Giorgos C. Karakousis, Gordon B. Mills, Yiling Lu, Tamer A. Ahmed, Poulikos I. Poulikakos, Giordano Caponigro, Markus Boehm, Malte Peters, Lynn M. Schuchter, Ashani T. Weeraratna, Meenhard Herlyn

    Published 2015
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  7. 7
    Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence

    Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence by Katherine R. Singleton, Lorin Crawford, Elizabeth Tsui, Haley E. Manchester, Ophélia Maertens, Xiaojing Liu, Maria V. Liberti, Anniefer N. Magpusao, Elizabeth M. Stein, Jennifer P. Tingley, Dennie T. Frederick, Genevieve M. Boland, Keith T. Flaherty, Shannon J. McCall, Clemens Krepler, Katrin Sproesser, Meenhard Herlyn, Drew Adams, Jason W. Locasale, Karen Cichowski, Sayan Mukherjee, Kris C. Wood

    Published 2017
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  8. 8
    Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma

    Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma by Jessie Villanueva, Jeffrey R. Infante, Clemens Krepler, Patricia Reyes-Uribe, Minu Samanta, Hsin‐Yi Chen, Bin Li, Rolf Swoboda, Melissa Wilson, Adina Vultur, Mizuho Fukunaba-Kalabis, Bradley Wubbenhorst, Thomas Y. Chen, Qin Liu, Katrin Sproesser, Douglas J. DeMarini, Tona M. Gilmer, Anne‐Marie Martin, Ronen Marmorstein, D. Schultz, David W. Speicher, Giorgos C. Karakousis, Wei Xu, Ravi K. Amaravadi, Xiaowei Xu, Lynn M. Schuchter, Meenhard Herlyn, Katherine L. Nathanson

    Published 2013
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  9. 9
    Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines

    Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines by Bradley Garman, Ioannis N. Anastopoulos, Clemens Krepler, Patricia Brafford, Katrin Sproesser, Yuchao Jiang, Bradley Wubbenhorst, Ravi K. Amaravadi, Joseph Bennett, Marilda Beqiri, David E. Elder, Keith T. Flaherty, Dennie T. Frederick, Tara C. Gangadhar, Michael J. Guarino, Dave S.�B. Hoon, Giorgos C. Karakousis, Qin Liu, Nandita Mitra, Nicholas J. Petrelli, Lynn M. Schuchter, Batool Shannan, Carol L. Shields, Jennifer A. Wargo, Brandon M. Wenz, Melissa Wilson, Min Xiao, Wei Xu, Xaiowei Xu, Xiangfan Yin, Nancy Zhang, Michael A. Davies, Meenhard Herlyn, Katherine L. Nathanson

    Published 2017
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  10. 10
    Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

    Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity by James Tsai, John Tayu Lee, Weiru Wang, Jiazhong Zhang, Hanna Cho, Shumeye Mamo, Ryan Bremer, S. Gillette, Jun Kong, Nikolas K. Haass, Katrin Sproesser, Ling Li, Keiran S.M. Smalley, Daniel W. Fong, Yongliang Zhu, Adhirai Marimuthu, Hoa Nguyen, Billy Lam, Jennifer Liu, Ivana Cheung, Julie Rice, Yoshihisa Suzuki, Catherine A. Luu, Calvin Settachatgul, Rafe Shellooe, John Cantwell, Sung‐Hou Kim, Joseph Schlessinger, Kam Y. J. Zhang, Brian L. West, Ben Powell, Gaston Habets, Chao Zhang, Prabha N. Ibrahim, Peter Hirth, Dean R. Artis, Meenhard Herlyn, Gideon Bollag

    Published 2008
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  11. 11
    Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

    Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors by Gao Zhang, Dennie T. Frederick, Lawrence W. Wu, Zhi Wei, Clemens Krepler, Satish Srinivasan, Young Chan Chae, Xiaowei Xu, Harry Choi, Elaida Dimwamwa, Omotayo Ope, Batool Shannan, Devraj Basu, Dongmei Zhang, Manti Guha, Min Xiao, Sergio Randell, Katrin Sproesser, Wei Xu, Jephrey Liu, Giorgos C. Karakousis, Lynn M. Schuchter, Tara C. Gangadhar, Ravi K. Amaravadi, Mengnan Gu, Caiyue Xu, Abheek Ghosh, Weiting Xu, Tian Tian, Jie Zhang, Shijie Zha, Qin Liu, Patricia Brafford, Ashani T. Weeraratna, Michael A. Davies, Jennifer A. Wargo, Narayan G. Avadhani, Yiling Lu, Gordon B. Mills, Dario C. Altieri, Keith T. Flaherty, Meenhard Herlyn

    Published 2016
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  12. 12
    PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

    PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas by Hezhe Lu, Shujing Liu, Gao Zhang, Bin Wu, Yueyao Zhu, Dennie T. Frederick, Yi Hu, Wenqun Zhong, Sergio Randell, Norah Sadek, Wei Zhang, Gang Chen, Chaoran Cheng, Jingwen Zeng, Lawrence W. Wu, Jie Zhang, Xiaoming Liu, Wei Xu, Clemens Krepler, Katrin Sproesser, Min Xiao, Benchun Miao, Jianglan Liu, Claire Song, Jephrey Y. Liu, Giorgos C. Karakousis, Lynn M. Schuchter, Yiling Lu, Gordon B. Mills, Yu‐Sheng Cong, Jonathan Chernoff, Jun Guo, Genevieve M. Boland, Ryan J. Sullivan, Zhi Wei, Jeffrey Field, Ravi K. Amaravadi, Keith T. Flaherty, Meenhard Herlyn, Xiaowei Xu, Wei Guo

    Published 2017
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  13. 13
    Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma

    Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma by Gao Zhang, Lawrence W. Wu, Ilgen Mender, Michal Barzily-Rokni, Marc R. Hammond, Omotayo Ope, Chaoran Cheng, Themistoklis Vasilopoulos, Sergio Randell, Norah Sadek, Aurelie Beroard, Min Xiao, Tian Tian, Jiufeng Tan, Umar Saeed, Eric Sugarman, Clemens Krepler, Patricia Brafford, Katrin Sproesser, Sengottuvelan Murugan, Rajasekharan Somasundaram, Bradley Garman, Bradley Wubbenhorst, Jonathan Woo, Xiangfan Yin, Qin Liu, Dennie T. Frederick, Benchun Miao, Wei Xu, Giorgos C. Karakousis, Xiaowei Xu, Lynn M. Schuchter, Tara C. Mitchell, Lawrence N. Kwong, Ravi K. Amaravadi, Yiling Lu, Genevieve M. Boland, Zhi Wei, Katherine L. Nathanson, Utz Herbig, Gordon B. Mills, Keith T. Flaherty, Meenhard Herlyn, Jerry W. Shay

    Published 2018
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  14. 14
    A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

    A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma by Clemens Krepler, Katrin Sproesser, Patricia Brafford, Marilda Beqiri, Bradley Garman, Min Xiao, Batool Shannan, Andrea Watters, Michela Perego, Gao Zhang, Adina Vultur, Xiangfan Yin, Qin Liu, Ioannis N. Anastopoulos, Bradley Wubbenhorst, Melissa Wilson, Wei Xu, Giorgos C. Karakousis, Michael D. Feldman, Xiaowei Xu, Ravi K. Amaravadi, Tara C. Gangadhar, David E. Elder, Lauren E. Haydu, Jennifer A. Wargo, Michael A. Davies, Yiling Lu, Gordon B. Mills, Dennie T. Frederick, Michal Barzily-Rokni, Keith T. Flaherty, Dave S.�B. Hoon, Michael J. Guarino, Joseph Bennett, R Ryan, Nicholas J. Petrelli, Carol L. Shields, Mizue Terai, Takami Sato, Andrew E. Aplin, Alexander Roesch, David B. Darr, Steven P. Angus, Rakesh Kumar, Ensar Halilovic, Giordano Caponigro, Sébastien Jeay, Jens Wuerthner, Annette O. Walter, Matthias Ocker, Matthew B. Boxer, Lynn M. Schuchter, Katherine L. Nathanson, Meenhard Herlyn

    Published 2017
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