Výsledky vyhledávání - Kashyap, Trinayan

The Calcium/Calcineurin Pathway Promotes Hemidesmosome Stability through Inhibition of β4 Integrin Phosphorylation Autor Kashyap, Trinayan, Rabinovitz, Isaac

Získat plný text Získat plný text Získat plný text

Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration Autor Kashyap, Trinayan, Germain, Emily, Roche, Michael, Lyle, Stephen, Rabinovitz, Isaac

Získat plný text Získat plný text Získat plný text

A Case Report of a 58-Year-Old Woman with a Diagnosis of High-Risk Myeloma Refractory to Multiple Line of Therapy and Treated with Selinexor, Bortezomib, and Dexamethasone Prior to... Autor Cass, Michael, McDonald, Andrew B., Ben-Shahar, Osnat, Landesman, Yosef, Kashyap, Trinayan

Získat plný text Získat plný text Získat plný text

Selective Inhibitors of Nuclear Export (SINE) compounds block proliferation and migration of triple negative breast cancer cells by restoring expression of ARRDC3 Autor Soung, Young Hwa, Kashyap, Trinayan, Nguyen, Thalia, Yadav, Garima, Chang, Hua, Landesman, Yosef, Chung, Jun

Získat plný text Získat plný text Získat plný text

HG-122 EFFECTS OF THE XPO1 INHIBITOR SELINEXOR ON THE NF-κB PATHWAY IN HIGH-GRADE GLIOMA AND DIFFUSE INTRINSIC PONTINE GLIOMA Autor DeSisto, John, Flannery, Patrick, Kashyap, Trinayan, Kung, Andrew, Venkataraman, Sujatha, Vibhakar, Rajeev, Landesman, Yosef, Green, Adam

Získat plný text Získat plný text

Clinical dosing regimen of selinexor maintains normal immune homeostasis and T cell effector function in mice: implications for combination with immunotherapy Autor Tyler, Paul M., Servos, Mariah M., de Vries, Romy C., Klebanov, Boris, Kashyap, Trinayan, Sacham, Sharon, Landesman, Yosef, Dougan, Michael, Dougan, Stephanie K.

Získat plný text Získat plný text Získat plný text

Selinexor synergizes with dexamethasone to repress mTORC1 signaling and induce multiple myeloma cell death Autor Argueta, Christian, Kashyap, Trinayan, Klebanov, Boris, Unger, Thaddeus J., Guo, Cathy, Harrington, Susie, Baloglu, Erkan, Lee, Margaret, Senapedis, William, Shacham, Sharon, Landesman, Yosef

Získat plný text Získat plný text Získat plný text

Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents Autor Kashyap, Trinayan, Argueta, Christian, Unger, Thaddeus, Klebanov, Boris, Debler, Sophia, Senapedis, William, Crochiere, Marsha L., Lee, Margaret S., Kauffman, Michael, Shacham, Sharon, Landesman, Yosef

Získat plný text Získat plný text Získat plný text

Selinexor, a novel selective inhibitor of nuclear export, reduces SARS-CoV-2 infection and protects the respiratory system in vivo Autor Kashyap, Trinayan, Murray, Jackelyn, Walker, Christopher J., Chang, Hua, Tamir, Sharon, Hou, Bing, Shacham, Sharon, Kauffman, Michael G., Tripp, Ralph A., Landesman, Yosef

Získat plný text Získat plný text Získat plný text

Biologic activity of the novel orally bioavailable selective inhibitor of nuclear export (SINE) KPT-335 against canine melanoma cell lines Autor Breit, Megan N, Kisseberth, William C, Bear, Misty D, Landesman, Yosef, Kashyap, Trinayan, McCauley, Dilara, Kauffman, Michael G, Shacham, Sharon, London, Cheryl A

Získat plný text Získat plný text Získat plný text

Selective nuclear export inhibitor KPT-330 enhances the antitumor activity of gemcitabine in human pancreatic cancer Autor Kazim, Sabiha, Malafa, Mokenge P., Coppola, Domenico, Husain, Kazim, Zibadi, Sherma, Kashyap, Trinayan, Crochiere, Marsha, Landesman, Yosef, Rashal, Tami, Sullivan, Daniel M., Mahipal, Amit

Získat plný text Získat plný text Získat plný text

Nuclear Export Inhibitor KPT-8602 Synergizes with PARP Inhibitors in Escalating Apoptosis in Castration Resistant Cancer Cells Autor Uddin, Md. Hafiz, Li, Yiwei, Khan, Husain Yar, Muqbil, Irfana, Aboukameel, Amro, Sexton, Rachel E., Reddy, Shriya, Landesman, Yosef, Kashyap, Trinayan, Azmi, Asfar S., Heath, Elisabeth I.

Získat plný text Získat plný text Získat plný text

XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myel... Autor Turner, Joel G., Kashyap, Trinayan, Dawson, Jana L., Gomez, Juan, Bauer, Alexis A., Grant, Steven, Dai, Yun, Shain, Kenneth H., Meads, Mark, Landesman, Yosef, Sullivan, Daniel M.

Získat plný text Získat plný text Získat plný text

Novel Small Molecule XPO1/CRM1 Inhibitors Induce Nuclear Accumulation of TP53, Phosphorylated MAPK and Apoptosis in Human Melanoma Cells Autor Yang, Jennifer, Bill, Matthew A., Young, Gregory S., La Perle, Krista, Landesman, Yosef, Shacham, Sharon, Kauffman, Michael, Senapedis, William, Kashyap, Trinayan, Saint-Martin, Jean-Richard, Kendra, Kari, Lesinski, Gregory B.

Získat plný text Získat plný text Získat plný text

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell dea... Autor Kashyap, Trinayan, Argueta, Christian, Aboukameel, Amro, Unger, Thaddeus John, Klebanov, Boris, Mohammad, Ramzi M., Muqbil, Irfana, Azmi, Asfar S., Drolen, Claire, Senapedis, William, Lee, Margaret, Kauffman, Michael, Shacham, Sharon, Landesman, Yosef

Získat plný text Získat plný text Získat plný text

The exportin-1 inhibitor selinexor exerts superior anti-tumor activity when combined with T cell checkpoint inhibitors Autor Farren, Matthew R., Hennessey, Rebecca C., Shakya, Reena, Elnaggar, Omar, Young, Gregory, Kendra, Kari, Landesman, Yosef, Elloul, Sivan, Crochiere, Marsha, Klebanov, Boris, Kashyap, Trinayan, Burd, Christin E., Lesinski, Gregory B.

Získat plný text Získat plný text Získat plný text

Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression Autor Aboukameel, Amro, Muqbil, Irfana, Baloglu, Erkan, Senapedis, William, Landesman, Yosef, Argueta, Christian, Kauffman, Michael, Chang, Hua, Kashyap, Trinayan, Shacham, Sharon, Neggers, Jasper E., Daelemans, Dirk, Heath, Elisabeth I., Azmi, Asfar S.

Získat plný text Získat plný text Získat plný text

XPO1 Inhibition Using Selinexor Synergizes With Chemotherapy in Acute Myeloid Leukemia (AML) by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus Autor Ranganathan, Parvathi, Kashyap, Trinayan, Yu, Xueyan, Meng, Xiaomei, Lai, Tzung-Huei, McNeil, Betina, Bhatnagar, Bhavana, Shacham, Sharon, Kauffman, Michael, Dorrance, Adrienne M., Blum, William, Sampath, Deepa, Landesman, Yosef, Garzon, Ramiro

Získat plný text Získat plný text Získat plný text

Selinexor-induced thrombocytopenia results from inhibition of thrombopoietin signaling in early megakaryopoiesis Autor Machlus, Kellie R., Wu, Stephen K., Vijey, Prakrith, Soussou, Thomas S., Liu, Zhi-Jian, Shacham, Eran, Unger, T. J., Kashyap, Trinayan, Klebanov, Boris, Sola-Visner, Martha, Crochiere, Marsha, Italiano, Joseph E., Landesman, Yosef

Získat plný text Získat plný text Získat plný text

Small molecule inhibitors of nuclear export ameliorate lupus by modulating plasma cell generation and survival Autor Rangel-Moreno, Javier, de la Luz Garcia-Hernandez, Maria, Owen, Teresa, Barnard, Jennifer, Becerril-Villanueva, Enrique, Kashyap, Trinayan, Argueta, Christian, Gamboa-Dominguez, Armando, Tamir, Sharon, Landesman, Yosef, Goldman, Bruce I., Ritchlin, Christopher T., Anolik, Jennifer H.

Získat plný text Získat plný text Získat plný text