Resultados de procura - Karl‐Heinz Altmann

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  1. 1
    Drugs from the Oceans: Marine Natural Products as Leads for Drug Discovery

    Drugs from the Oceans: Marine Natural Products as Leads for Drug Discovery por Karl‐Heinz Altmann

    Publicado 2017
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  2. 2
    Resorcylic acid lactones as new lead structures for kinase inhibition

    Resorcylic acid lactones as new lead structures for kinase inhibition por Tatjana Hofmann, Karl‐Heinz Altmann

    Publicado 2008
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  3. 3
    Recent developments in natural product-based drug discovery for tuberculosis

    Recent developments in natural product-based drug discovery for tuberculosis por Maryline Dong, Bernhard Pfeiffer, Karl‐Heinz Altmann

    Publicado 2016
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  4. 4
    Structure-Activity Relationship Studies on the Macrolide Exotoxin Mycolactone of Mycobacterium ulcerans

    Structure-Activity Relationship Studies on the Macrolide Exotoxin Mycolactone of Mycobacterium ulcerans por Nicole Scherr, Philipp Gersbach, Jean‐Pierre Dangy, Claudio Bomio, Jun Li, Karl‐Heinz Altmann, Gerd Pluschke

    Publicado 2013
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  5. 5
    GABAA receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts

    GABAA receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts por Dietmar Benke, Andrea Barberis, Sascha Kopp, Karl‐Heinz Altmann, Monika Schubiger, Kaspar E. Vogt, Uwe Rudolph, Hanns Möhler

    Publicado 2008
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  6. 6
    The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model

    The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model por Pascal Häfliger, Julien Graff, Matthias Rubin, Amandine Stooss, Matthias S. Dettmer, Karl‐Heinz Altmann, Jürg Gertsch, Roch‐Philippe Charles

    Publicado 2018
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  7. 7
    Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents

    Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents por A.E. Prota, Katja Bargsten, Didier Zurwerra, Jessica J. Field, J. Fernando Dı́az, Karl‐Heinz Altmann, Michel O. Steinmetz

    Publicado 2013
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  8. 8
    Alkylamides from Echinacea Are a New Class of Cannabinomimetics

    Alkylamides from Echinacea Are a New Class of Cannabinomimetics por Stefan Raduner, Adriana Majewska, Jian‐Zhong Chen, Xiang‐Qun Xie, Jacques Hamon, Bernard Faller, Karl‐Heinz Altmann, Jürg Gertsch

    Publicado 2006
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  9. 9
    Beta-caryophyllene is a dietary cannabinoid

    Beta-caryophyllene is a dietary cannabinoid por Jürg Gertsch, Marco Leonti, Stefan Raduner, Ildikó Rácz, Jian‐Zhong Chen, Xiang‐Qun Xie, Karl‐Heinz Altmann, Meliha Karsak, Andreas Zimmer

    Publicado 2008
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  10. 10
    Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter

    Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter por Renhong Yan, Yaning Li, Jennifer Müller, Yuanyuan Zhang, Simon Singer, Lu Xia, Xinyue Zhong, Jürg Gertsch, Karl‐Heinz Altmann, Qiang Zhou

    Publicado 2021
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  11. 11
    Towards a new tuberculosis drug: pyridomycin – nature's isoniazid

    Towards a new tuberculosis drug: pyridomycin – nature's isoniazid por Ruben C. Hartkoorn, Claudia Sala, João Neres, Florence Pojer, Sophie Magnet, Raju Mukherjee, Swapna Uplekar, Stefanie Boy‐Röttger, Karl‐Heinz Altmann, Stewart T. Cole

    Publicado 2012
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  12. 12
    Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans

    Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans por Jean‐Pierre Dangy, Nicole Scherr, Philipp Gersbach, Melanie N. Hug, Raphael Bieri, Claudio Bomio, Jun Li, Sylwia Huber, Karl‐Heinz Altmann, Gerd Pluschke

    Publicado 2016
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  13. 13
    RNA polymerase motions during promoter melting

    RNA polymerase motions during promoter melting por Andrey Feklístov, Brian Bae, J. Hauver, Agnieszka Lass-Napiorkowska, Markus Kalesse, Florian Glaus, Karl‐Heinz Altmann, Tomasz Heyduk, Robert Landick, Seth A. Darst

    Publicado 2017
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  14. 14
    A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

    A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs por A.E. Prota, Katja Bargsten, J. Fernando Dı́az, M. Marsh, Carmen Cuevas, Marc Liniger, Christian Neuhaus, José M. Andreu, Karl‐Heinz Altmann, Michel O. Steinmetz

    Publicado 2014
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  15. 15
    Fragment‐Based De Novo Design Reveals a Small‐Molecule Inhibitor of <i>Helicobacter Pylori</i> HtrA

    Fragment‐Based De Novo Design Reveals a Small‐Molecule Inhibitor of <i>Helicobacter Pylori</i> HtrA por Anna Maria Perna, Tiago Rodrigues, Thomas P. Schmidt, Manja Böhm, Katharina Stutz, Daniel Reker, Bernhard Pfeiffer, Karl‐Heinz Altmann, Steffen Backert, Silja Weßler, Gisbert Schneider

    Publicado 2015
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  16. 16
    Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C- <i>raf</i> kinase supports an antisense mechanism of action <i>in vivo</i>

    Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C- <i>raf</i> kinase supports an antisense mechanism of action <i>in vivo</i> por Brett P. Monia, Henri Sasmor, Joseph F. Johnston, Susan M. Freier, Elena A. Lesnik, Marcel A. Müller, Thomas Geiger, Karl‐Heinz Altmann, Heinz E. Moser, Doriano Fabbro

    Publicado 1996
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  17. 17
    A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

    A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin por Grégory Menchon, A.E. Prota, Daniel Lucena‐Agell, Pascal Bucher, Rolf Jansen, Herbert Irschik, Rolf Müller, Ian Paterson, J. Fernando Dı́az, Karl‐Heinz Altmann, Michel O. Steinmetz

    Publicado 2018
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  18. 18
    Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis

    Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis por Caroline S. Foo, Andréanne Lupien, Maryline Kienle, Anthony Vocat, Andrej Benjak, Raphael Sommer, Dirk A. Lamprecht, Adrie J. C. Steyn, Kévin Pethe, Jérémie Piton, Karl‐Heinz Altmann, Stewart T. Cole

    Publicado 2018
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  19. 19
    Structural basis of small-molecule inhibition of human multidrug transporter ABCG2

    Structural basis of small-molecule inhibition of human multidrug transporter ABCG2 por Scott M. Jackson, Ioannis Manolaridis, Julia Kowal, Melanie Zechner, Nicholas M. I. Taylor, Manuel Bause, Stefanie Bauer, R. Bartholomaeus, G. Bernhardt, Burkhard Koenig, Armin Buschauer, Henning Stahlberg, Karl‐Heinz Altmann, Kaspar P. Locher

    Publicado 2018
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  20. 20
    Taxanes convert regions of perturbed microtubule growth into rescue sites

    Taxanes convert regions of perturbed microtubule growth into rescue sites por Ankit Rai, Tianyang Liu, Simon Glauser, Eugene A. Katrukha, Juan Estévez-Gallego, Ruddi Rodríguez-García, Wei‐Shuo Fang, J. Fernando Dı́az, Michel O. Steinmetz, Karl‐Heinz Altmann, Lukas C. Kapitein, Carolyn A. Moores, Anna Akhmanova

    Publicado 2019
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