检索结果 - Kaether, Christoph

A lipid boundary separates APP and secretases and limits amyloid β-peptide generation 由 Kaether, Christoph, Haass, Christian

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Polar Transmembrane-based Amino Acids in Presenilin 1 Are Involved in Endoplasmic Reticulum Localization, Pen2 Protein Binding, and γ-Secretase Complex Stabilization 由 Fassler, Matthias, Li, Xiaolin, Kaether, Christoph

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A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways 由 Behrendt, Laura, Kurth, Ingo, Kaether, Christoph

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Axonal Membrane Proteins Are Transported in Distinct Carriers: A Two-Color Video Microscopy Study in Cultured Hippocampal Neurons 由 Kaether, Christoph, Skehel, Paul, Dotti, Carlos G.

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Trafficking and Proteolytic Processing of APP 由 Haass, Christian, Kaether, Christoph, Thinakaran, Gopal, Sisodia, Sangram

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Disrupted-in-Schizophrenia 1 (DISC1) Is Necessary for the Correct Migration of Cortical Interneurons 由 Steinecke, André, Gampe, Christin, Valkova, Christina, Kaether, Christoph, Bolz, Jürgen

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The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels 由 Valkova, Christina, Liebmann, Lutz, Krämer, Andreas, Hübner, Christian A., Kaether, Christoph

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Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle 由 Ahrens, Hellen E., Huettemeister, Judith, Schmidt, Manuel, Kaether, Christoph, von Maltzahn, Julia

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Modulation of Mutant Huntingtin N-Terminal Cleavage and Its Effect on Aggregation and Cell Death 由 Juenemann, Katrin, Weisse, Christina, Reichmann, Denise, Kaether, Christoph, Calkhoven, Cornelis F., Schilling, Gabriele

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The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity 由 Kaether, Christoph, Capell, Anja, Edbauer, Dieter, Winkler, Edith, Novak, Bozidar, Steiner, Harald, Haass, Christian

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Microtubule-dependent Recruitment of Staufen-Green Fluorescent Protein into Large RNA-containing Granules and Subsequent Dendritic Transport in Living Hippocampal Neurons 由 Köhrmann, Martin, Luo, Ming, Kaether, Christoph, DesGroseillers, Luc, Dotti, Carlos G., Kiebler, Michael A.

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Klotho is a substrate for α-, β- and γ-secretase 由 Bloch, Laura, Sineshchekova, Olga, Reichenbach, Daniela, Reiss, Karina, Saftig, Paul, Kuro-o, Makoto, Kaether, Christoph

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Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled α-subunits 由 Valkova, Christina, Albrizio, Marina, Röder, Ira V., Schwake, Michael, Betto, Romeo, Rudolf, Rüdiger, Kaether, Christoph

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Presenilin-1 affects trafficking and processing of βAPP and is targeted in a complex with nicastrin to the plasma membrane 由 Kaether, Christoph, Lammich, Sven, Edbauer, Dieter, Ertl, Michaela, Rietdorf, Jens, Capell, Anja, Steiner, Harald, Haass, Christian

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NOD2-C2 - a novel NOD2 isoform activating NF-κB in a muramyl dipeptide-independent manner 由 Kramer, Marcel, Boeck, Janne, Reichenbach, Daniela, Kaether, Christoph, Schreiber, Stefan, Platzer, Matthias, Rosenstiel, Philip, Huse, Klaus

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The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)(+) RNA Export 由 Port, Sarah A., Mendes, Adélia, Valkova, Christina, Spillner, Christiane, Fahrenkrog, Birthe, Kaether, Christoph, Kehlenbach, Ralph H.

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The GxGD Motif of Presenilin Contributes to Catalytic Function and Substrate Identification of γ-Secretase 由 Yamasaki, Aya, Eimer, Stefan, Okochi, Masayasu, Smialowska, Agata, Kaether, Christoph, Baumeister, Ralf, Haass, Christian, Steiner, Harald

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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity 由 Friedrich, Ralf P., Tepper, Katharina, Rönicke, Raik, Soom, Malle, Westermann, Martin, Reymann, Klaus, Kaether, Christoph, Fändrich, Marcus

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Notch1 signaling is mediated by importins alpha 3, 4, and 7 由 Huenniger, Kerstin, Krämer, Andreas, Soom, Malle, Chang, Iree, Köhler, Matthias, Depping, Reinhard, Kehlenbach, Ralph H., Kaether, Christoph

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Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence 由 Marthandan, Shiva, Menzel, Uwe, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Kaether, Christoph, Diekmann, Stephan

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