Risultati della ricerca - Kaether, Christoph

A lipid boundary separates APP and secretases and limits amyloid β-peptide generation di Kaether, Christoph, Haass, Christian

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Polar Transmembrane-based Amino Acids in Presenilin 1 Are Involved in Endoplasmic Reticulum Localization, Pen2 Protein Binding, and γ-Secretase Complex Stabilization di Fassler, Matthias, Li, Xiaolin, Kaether, Christoph

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A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways di Behrendt, Laura, Kurth, Ingo, Kaether, Christoph

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Axonal Membrane Proteins Are Transported in Distinct Carriers: A Two-Color Video Microscopy Study in Cultured Hippocampal Neurons di Kaether, Christoph, Skehel, Paul, Dotti, Carlos G.

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Trafficking and Proteolytic Processing of APP di Haass, Christian, Kaether, Christoph, Thinakaran, Gopal, Sisodia, Sangram

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Disrupted-in-Schizophrenia 1 (DISC1) Is Necessary for the Correct Migration of Cortical Interneurons di Steinecke, André, Gampe, Christin, Valkova, Christina, Kaether, Christoph, Bolz, Jürgen

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The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels di Valkova, Christina, Liebmann, Lutz, Krämer, Andreas, Hübner, Christian A., Kaether, Christoph

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Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle di Ahrens, Hellen E., Huettemeister, Judith, Schmidt, Manuel, Kaether, Christoph, von Maltzahn, Julia

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Modulation of Mutant Huntingtin N-Terminal Cleavage and Its Effect on Aggregation and Cell Death di Juenemann, Katrin, Weisse, Christina, Reichmann, Denise, Kaether, Christoph, Calkhoven, Cornelis F., Schilling, Gabriele

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The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity di Kaether, Christoph, Capell, Anja, Edbauer, Dieter, Winkler, Edith, Novak, Bozidar, Steiner, Harald, Haass, Christian

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Microtubule-dependent Recruitment of Staufen-Green Fluorescent Protein into Large RNA-containing Granules and Subsequent Dendritic Transport in Living Hippocampal Neurons di Köhrmann, Martin, Luo, Ming, Kaether, Christoph, DesGroseillers, Luc, Dotti, Carlos G., Kiebler, Michael A.

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Klotho is a substrate for α-, β- and γ-secretase di Bloch, Laura, Sineshchekova, Olga, Reichenbach, Daniela, Reiss, Karina, Saftig, Paul, Kuro-o, Makoto, Kaether, Christoph

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Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled α-subunits di Valkova, Christina, Albrizio, Marina, Röder, Ira V., Schwake, Michael, Betto, Romeo, Rudolf, Rüdiger, Kaether, Christoph

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Presenilin-1 affects trafficking and processing of βAPP and is targeted in a complex with nicastrin to the plasma membrane di Kaether, Christoph, Lammich, Sven, Edbauer, Dieter, Ertl, Michaela, Rietdorf, Jens, Capell, Anja, Steiner, Harald, Haass, Christian

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NOD2-C2 - a novel NOD2 isoform activating NF-κB in a muramyl dipeptide-independent manner di Kramer, Marcel, Boeck, Janne, Reichenbach, Daniela, Kaether, Christoph, Schreiber, Stefan, Platzer, Matthias, Rosenstiel, Philip, Huse, Klaus

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The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)(+) RNA Export di Port, Sarah A., Mendes, Adélia, Valkova, Christina, Spillner, Christiane, Fahrenkrog, Birthe, Kaether, Christoph, Kehlenbach, Ralph H.

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The GxGD Motif of Presenilin Contributes to Catalytic Function and Substrate Identification of γ-Secretase di Yamasaki, Aya, Eimer, Stefan, Okochi, Masayasu, Smialowska, Agata, Kaether, Christoph, Baumeister, Ralf, Haass, Christian, Steiner, Harald

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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity di Friedrich, Ralf P., Tepper, Katharina, Rönicke, Raik, Soom, Malle, Westermann, Martin, Reymann, Klaus, Kaether, Christoph, Fändrich, Marcus

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Notch1 signaling is mediated by importins alpha 3, 4, and 7 di Huenniger, Kerstin, Krämer, Andreas, Soom, Malle, Chang, Iree, Köhler, Matthias, Depping, Reinhard, Kehlenbach, Ralph H., Kaether, Christoph

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Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence di Marthandan, Shiva, Menzel, Uwe, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Kaether, Christoph, Diekmann, Stephan

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