Canlyniadau Chwilio - Kaether, Christoph

A lipid boundary separates APP and secretases and limits amyloid β-peptide generation gan Kaether, Christoph, Haass, Christian

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Polar Transmembrane-based Amino Acids in Presenilin 1 Are Involved in Endoplasmic Reticulum Localization, Pen2 Protein Binding, and γ-Secretase Complex Stabilization gan Fassler, Matthias, Li, Xiaolin, Kaether, Christoph

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A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways gan Behrendt, Laura, Kurth, Ingo, Kaether, Christoph

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Axonal Membrane Proteins Are Transported in Distinct Carriers: A Two-Color Video Microscopy Study in Cultured Hippocampal Neurons gan Kaether, Christoph, Skehel, Paul, Dotti, Carlos G.

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Trafficking and Proteolytic Processing of APP gan Haass, Christian, Kaether, Christoph, Thinakaran, Gopal, Sisodia, Sangram

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Disrupted-in-Schizophrenia 1 (DISC1) Is Necessary for the Correct Migration of Cortical Interneurons gan Steinecke, André, Gampe, Christin, Valkova, Christina, Kaether, Christoph, Bolz, Jürgen

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The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels gan Valkova, Christina, Liebmann, Lutz, Krämer, Andreas, Hübner, Christian A., Kaether, Christoph

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Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle gan Ahrens, Hellen E., Huettemeister, Judith, Schmidt, Manuel, Kaether, Christoph, von Maltzahn, Julia

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Modulation of Mutant Huntingtin N-Terminal Cleavage and Its Effect on Aggregation and Cell Death gan Juenemann, Katrin, Weisse, Christina, Reichmann, Denise, Kaether, Christoph, Calkhoven, Cornelis F., Schilling, Gabriele

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The presenilin C-terminus is required for ER-retention, nicastrin-binding and γ-secretase activity gan Kaether, Christoph, Capell, Anja, Edbauer, Dieter, Winkler, Edith, Novak, Bozidar, Steiner, Harald, Haass, Christian

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Microtubule-dependent Recruitment of Staufen-Green Fluorescent Protein into Large RNA-containing Granules and Subsequent Dendritic Transport in Living Hippocampal Neurons gan Köhrmann, Martin, Luo, Ming, Kaether, Christoph, DesGroseillers, Luc, Dotti, Carlos G., Kiebler, Michael A.

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Klotho is a substrate for α-, β- and γ-secretase gan Bloch, Laura, Sineshchekova, Olga, Reichenbach, Daniela, Reiss, Karina, Saftig, Paul, Kuro-o, Makoto, Kaether, Christoph

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Sorting receptor Rer1 controls surface expression of muscle acetylcholine receptors by ER retention of unassembled α-subunits gan Valkova, Christina, Albrizio, Marina, Röder, Ira V., Schwake, Michael, Betto, Romeo, Rudolf, Rüdiger, Kaether, Christoph

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Presenilin-1 affects trafficking and processing of βAPP and is targeted in a complex with nicastrin to the plasma membrane gan Kaether, Christoph, Lammich, Sven, Edbauer, Dieter, Ertl, Michaela, Rietdorf, Jens, Capell, Anja, Steiner, Harald, Haass, Christian

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NOD2-C2 - a novel NOD2 isoform activating NF-κB in a muramyl dipeptide-independent manner gan Kramer, Marcel, Boeck, Janne, Reichenbach, Daniela, Kaether, Christoph, Schreiber, Stefan, Platzer, Matthias, Rosenstiel, Philip, Huse, Klaus

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The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)(+) RNA Export gan Port, Sarah A., Mendes, Adélia, Valkova, Christina, Spillner, Christiane, Fahrenkrog, Birthe, Kaether, Christoph, Kehlenbach, Ralph H.

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The GxGD Motif of Presenilin Contributes to Catalytic Function and Substrate Identification of γ-Secretase gan Yamasaki, Aya, Eimer, Stefan, Okochi, Masayasu, Smialowska, Agata, Kaether, Christoph, Baumeister, Ralf, Haass, Christian, Steiner, Harald

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Mechanism of amyloid plaque formation suggests an intracellular basis of Aβ pathogenicity gan Friedrich, Ralf P., Tepper, Katharina, Rönicke, Raik, Soom, Malle, Westermann, Martin, Reymann, Klaus, Kaether, Christoph, Fändrich, Marcus

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Notch1 signaling is mediated by importins alpha 3, 4, and 7 gan Huenniger, Kerstin, Krämer, Andreas, Soom, Malle, Chang, Iree, Köhler, Matthias, Depping, Reinhard, Kehlenbach, Ralph H., Kaether, Christoph

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Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence gan Marthandan, Shiva, Menzel, Uwe, Priebe, Steffen, Groth, Marco, Guthke, Reinhard, Platzer, Matthias, Hemmerich, Peter, Kaether, Christoph, Diekmann, Stephan

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