Søgeresultater - Juan Castillo‐Fernandez

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  1. 1
    Epigenetics of discordant monozygotic twins: implications for disease

    Epigenetics of discordant monozygotic twins: implications for disease af Juan Castillo‐Fernandez, Tim D. Spector, Jordana T. Bell

    Udgivet 2014
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  2. 2
    Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes

    Transcriptome and DNA methylation profiling during the NSN to SN transition in mouse oocytes af Hannah Demond, Soumen Khan, Juan Castillo‐Fernandez, Courtney W. Hanna, Gavin Kelsey

    Udgivet 2025
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  3. 3
    Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis

    Increased transcriptome variation and localised DNA methylation changes in oocytes from aged mice revealed by parallel single‐cell analysis af Juan Castillo‐Fernandez, E. Herrera-Puerta, Hannah Demond, Stephen J. Clark, Courtney W. Hanna, Myriam Hemberger, Gavin Kelsey

    Udgivet 2020
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  4. 4
    Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation

    Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation af Caroline Le Roy, Ruth C. E. Bowyer, Juan Castillo‐Fernandez, Tess Pallister, Cristina Menni, Claire J. Steves, Sarah Berry, Tim D. Spector, Jordana T. Bell

    Udgivet 2019
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  5. 5
    DNA methylation age and physical and cognitive ageing

    DNA methylation age and physical and cognitive ageing af Jane Maddock, Juan Castillo‐Fernandez, Andrew Wong, Rachel Cooper, Marcus Richards, Ken K. Ong, George B. Ploubidis, Alissa Goodman, Diana Kuh, Jordana T. Bell, Rebecca Hardy

    Udgivet 2019
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  6. 6
    Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis

    Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis af Hannah Demond, Courtney W. Hanna, Juan Castillo‐Fernandez, Fátima Santos, Evangelia K. Papachristou, Anne Segonds-Pichon, Kamal Kishore, Simon Andrews, Clive S. D’Santos, Gavin Kelsey

    Udgivet 2023
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  7. 7
    DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

    DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation af Juan Castillo‐Fernandez, Yuk Jing Loke, Sebastian Bass-Stringer, Fei Gao, Yudong Xia, Honglong Wu, Hanlin Lu, Yuan Liu, Jun Wang, Tim D. Spector, Richard Saffery, Jeffrey M. Craig, Jordana T. Bell

    Udgivet 2017
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  8. 8
    Epigenetic findings in periodontitis in UK twins: a cross-sectional study

    Epigenetic findings in periodontitis in UK twins: a cross-sectional study af Yuko Kurushima, Pei-Chien Tsai, Juan Castillo‐Fernandez, Alexessander Couto Alves, Julia S. El-Sayed Moustafa, Caroline Le Roy, Tim D. Spector, Mark Ide, Francis J. Hughes, Kerrin S. Small, Claire J. Steves, Jordana T. Bell

    Udgivet 2019
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  9. 9
    Identification of a unique epigenetic profile in women with diminished ovarian reserve

    Identification of a unique epigenetic profile in women with diminished ovarian reserve af Kristina Wendelboe Olsen, Juan Castillo‐Fernandez, Andrew Cho Chan, Nina la Cour Freiesleben, Anne Zedeler, Mona Bungum, Alexia Cardona, John R. B. Perry, Sven O. Skouby, Eva R. Hoffmann, Gavin Kelsey, Marie Louise Grøndahl

    Udgivet 2020
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  10. 10
    A distinctive epigenetic ageing profile in human granulosa cells

    A distinctive epigenetic ageing profile in human granulosa cells af Kristina Wendelboe Olsen, Juan Castillo‐Fernandez, Anne Zedeler, Nina la Cour Freiesleben, M. Bungum, Andrew Cho Chan, Alexia Cardona, John R. B. Perry, Sven O. Skouby, Rehannah Borup, Eva R. Hoffmann, Gavin Kelsey, Marie Louise Grøndahl

    Udgivet 2020
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  11. 11
    Genetic impacts on DNA methylation help elucidate regulatory genomic processes

    Genetic impacts on DNA methylation help elucidate regulatory genomic processes af Sergio Villicaña, Juan Castillo‐Fernandez, Eilís Hannon, Colette Christiansen, Pei-Chien Tsai, Jane Maddock, Diana Kuh, Matthew Suderman, Christopher Power, Caroline L. Relton, George B. Ploubidis, Andrew Wong, Rebecca Hardy, Alissa Goodman, Ken K. Ong, Jordana T. Bell

    Udgivet 2023
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  12. 12
    Estrogen and COVID-19 symptoms: Associations in women from the COVID Symptom Study

    Estrogen and COVID-19 symptoms: Associations in women from the COVID Symptom Study af Ricardo Costeira, Karla A. Lee, Benjamin Murray, Colette Christiansen, Juan Castillo‐Fernandez, Mary Ní Lochlainn, Joan Capdevila Pujol, Heather Macfarlane, Louise C. Kenny, Iain Buchan, Jonathan Wolf, Janice Rymer, Sébastien Ourselin, Claire J. Steves, Timothy D. Spector, Louise Newson, Jordana T. Bell

    Udgivet 2021
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  13. 13
    Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density

    Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density af John Morris, Pei-Chien Tsai, Roby Joehanes, Jie Zheng, Katerina Trajanoska, Mette Soerensen, Vincenzo Forgetta, Juan Castillo‐Fernandez, Morten Frost, Tim D. Spector, Kaare Christensen, Lene Christiansen, Fernando Rivadeneira, Jonathan H. Tobias, David M. Evans, Douglas P. Kiel, Yi‐Hsiang Hsu, J. Brent Richards, Jordana T. Bell

    Udgivet 2017
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  14. 14
    Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

    Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health af Pei-Chien Tsai, Craig A. Glastonbury, Melissa Eliot, Sailalitha Bollepalli, İdil Yet, Juan Castillo‐Fernandez, Elena Carnero‐Montoro, Thomas Hardiman, Tiphaine Martin, Alice Vickers, Massimo Mangino, Kirsten Ward, Kirsi H. Pietiläinen, Panos Deloukas, Tim D. Spector, Ana Viñuela, Eric B. Loucks, Miina Ollikainen, Karl T. Kelsey, Kerrin S. Small, Jordana T. Bell

    Udgivet 2018
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  15. 15
    Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice

    Epigenetic changes induced by in utero dietary challenge result in phenotypic variability in successive generations of mice af Mathew Van de Pette, Andrew Dimond, António Galvão, Steven J. Millership, Wilson To, Chiara Prodani, Gráinne I. McNamara, Ludovica Bruno, Alessandro Sardini, Zoë Webster, James McGinty, Paul M. W. French, Anthony G. Uren, Juan Castillo‐Fernandez, William MD Watkinson, Anne C. Ferguson‐Smith, Matthias Merkenschlager, Rosalind M. John, Gavin Kelsey, Amanda G. Fisher

    Udgivet 2022
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  16. 16
    Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects

    Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects af Colette Christiansen, Juan Castillo‐Fernandez, Arce Domingo‐Relloso, Wei Zhao, Julia S. El-Sayed Moustafa, Pei-Chien Tsai, Jane Maddock, Karin Haack, Shelley A. Cole, Sharon L. R. Kardia, Mariam Molokhia, Matthew Suderman, Chris Power, Caroline L. Relton, Andrew Wong, Diana Kuh, A. Goodman, Kerrin S. Small, Jennifer A. Smith, María Téllez-Plaza, Ana Navas‐Acién, George B. Ploubidis, Rebecca Hardy, Jordana T. Bell

    Udgivet 2021
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  17. 17
    Identical twins carry a persistent epigenetic signature of early genome programming

    Identical twins carry a persistent epigenetic signature of early genome programming af Jenny van Dongen, Scott D. Gordon, Allan F. McRae, Veronika V. Odintsova, Hamdi Mbarek, Charles E. Breeze, Karen Sugden, Sara Lundgren, Juan Castillo‐Fernandez, Eilís Hannon, Terrie E. Moffitt, Fiona A. Hagenbeek, C.E.M. van Beijsterveldt, Jouke‐Jan Hottenga, Pei-Chien Tsai, Jenny van Dongen, Jouke‐Jan Hottenga, Allan F. McRae, Karen Sugden, Juan Castillo‐Fernandez, Eilís Hannon, Terrie E. Moffitt, Jouke‐Jan Hottenga, Eco J. C. de Geus, Timothy D. Spector, Josine L. Min, Gibran Hemani, Erik A. Ehli, Franziska Paul, Claudio D. Stern, Bastiaan T. Heijmans, P. Eline Slagboom, Lucia Daxinger, Silvère M. van der Maarel, Eco J. C. de Geus, Gonneke Willemsen, Grant W. Montgomery, Bruno Reversade, Miina Ollikainen, Jaakko Kaprio, Tim D. Spector, Jordana T. Bell, Jonathan Mill, Avshalom Caspi, Nicholas G. Martin, Dorret I. Boomsma

    Udgivet 2021
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  18. 18
    Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes

    Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes af Liam McAllan, Damir Baranašić, Sergio Villicaña, Scarlett Brown, Weihua Zhang, Benjamin Lehne, Marco Adamo, Andrew Jenkinson, Mohamed Elkalaawy, Borzoueh Mohammadi, Majid Hashemi, Nadia Fernandes, Nathalie Lambie, Richard T. Williams, Colette Christiansen, Youwen Yang, Liudmila Zudina, Vasiliki Lagou, Sili Tan, Juan Castillo‐Fernandez, James W. D. King, Richie Soong, Paul Elliott, Berthold Lausen, Inga Prokopenko, Inês Cebola, Marie Loh, Boris Lenhard, Rachel L. Batterham, Jordana T. Bell, John C. Chambers, Jaspal S. Kooner, William R. Scott

    Udgivet 2023
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  19. 19
    Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

    Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption af Irma Karabegović, Eliana Portilla-Fernández, Yang Li, Jiantao Ma, Silvana C. E. Maas, Daokun Sun, Emily Hu, Brigitte Kühnel, Yan Zhang, Srikant Ambatipudi, Giovanni Fiorito, Jian Huang, Juan Castillo‐Fernandez, Kerri L. Wiggins, Niek de Klein, Sara Grioni, Brenton R. Swenson, Silvia Polidoro, Jorien L. Treur, Cyrille Cuenin, Pei-Chien Tsai, Ricardo Costeira, Véronique Chajès, Kim V.E. Braun, Niek Verweij, Anja Kretschmer, Lude Franke, Joyce B. J. van Meurs, André G. Uitterlinden, Robert J. de Knegt, M. Arfan Ikram, Abbas Dehghan, Annette Peters, Ben Schöttker, Sina A. Gharib, Nona Sotoodehnia, Jordana T. Bell, Paul Elliott, Paolo Vineis, Caroline L. Relton, Zdenko Herceg, Hermann Brenner, Mélanie Waldenberger, Casey M. Rebholz, Trudy Voortman, Qiuwei Pan, Myriam Fornage, Daniel Levy, Manfred Kayser, Mohsen Ghanbari

    Udgivet 2021
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  20. 20
    Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

    Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals af Pooja R. Mandaviya, Roby Joehanes, Jennifer A. Brody, Juan Castillo‐Fernandez, Koen F. Dekkers, Anh N., Mariaelisa Graff, Ismo Hänninen, Toshiko Tanaka, Ester AL de Jonge, Jessica C. Kiefte‐de Jong, Devin Absher, Stella Aslibekyan, Yolanda B. de Rijke, Myriam Fornage, Dena Hernández, Mikko Hurme, M. Arfan Ikram, Paul F. Jacques, Anne E. Justice, Douglas P. Kiel, Rozenn N. Lemaître, Michael Mendelson, Vera Mikkilä, Ann Zenobia Moore, Tess Pallister, Olli Raitakari, Casper G. Schalkwijk, Jin Sha, Eline P. E. Slagboom, Caren E. Smith, Coen D.A. Stehouwer, Pei-Chien Tsai, André G. Uitterlinden, Carla Kallen, Alan B. Zonderman, Donna K. Arnett, Stefania Bandinelli, Jordana T. Bell, Bastiaan T. Heijmans, Terho Lehtimäki, Daniel Levy, Kari E. North, Nona Sotoodehnia, Marleen M. J. van Greevenbroek, Joyce B. J. van Meurs, Sandra G. Heil

    Udgivet 2019
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