Výsledky vyhledávání - Jousma, Edwin

An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system Autor Choi, Kwangmin, Komurov, Kakajan, Fletcher, Jonathan S., Jousma, Edwin, Cancelas, Jose A., Wu, Jianqiang, Ratner, Nancy

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STAT3 inhibition reduces macrophage number and tumor growth in neurofibroma Autor Fletcher, Jonathan S., Springer, Mitchell G., Choi, Kwangmin, Jousma, Edwin, Rizvi, Tilat A., Dombi, Eva, Kim, Mi-Ok, Wu, Jianqiang, Ratner, Nancy

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Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of neurofibromatosis type 1 Autor Jousma, Edwin, Rizvi, Tilat A., Wu, Jianqiang, Janhofer, David, Dombi, Eva, Dunn, Richard S., Kim, Mi-Ok, Masters, Andrea R., Jones, David R., Cripe, Timothy P., Ratner, Nancy

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Preclincial Testing of Sorafenib and RAD001 in the Nf (fl/fl);DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging Autor Wu, Jianqiang, Dombi, Eva, Jousma, Edwin, Dunn, R. Scott, Lindquist, Diana, Schnell, Beverly M., Kim, Mi-Ok, Kim, AeRang, Widemann, Brigitte C., Cripe, Timothy P., Ratner, Nancy

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EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors Autor Wu, Jianqiang, Patmore, Deanna M., Jousma, Edwin, Eaves, David W., Breving, Kimberly, Patel, Ami V., Schwartz, Eric B., Fuchs, James R., Cripe, Timothy P., Stemmer-Rachamimov, Anat O., Ratner, Nancy

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Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition Autor Prada, Carlos E., Jousma, Edwin, Rizvi, Tilat A., Wu, Jianqiang, Dunn, R. Scott, Mayes, Debra A., Cancelas, Jose A., Dombi, Eva, Kim, Mi-Ok, West, Brian L., Bollag, Gideon, Ratner, Nancy

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PM-18 EGFR-STAT3 ACTIVATES β-CATENIN SIGNALING TO DRIVE NEUROFIBROMA INITIATION IN NF1, AND PLAYS A ROLE IN TUMOR MAINTENANCE Autor Ratner, Nancy, Keng, Vincent, Patmore, Deanna M., Kendall, Jed K., Jousma, Edwin, Choi, Kwangmin, Fan, Danhua, Schwartz, Eric B., Fuchs, James R., Zou, Yuanshu, Kim, Mi-Ok, Dombi, Eva, Levy, David E., Cancelas, Jose A., Stemmer-Rachamimov, Anat, Spinner, Robert J., Largaespada, David A.

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MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors Autor Jessen, Walter J., Miller, Shyra J., Jousma, Edwin, Wu, Jianqiang, Rizvi, Tilat A., Brundage, Meghan E., Eaves, David, Widemann, Brigitte, Kim, Mi-Ok, Dombi, Eva, Sabo, Jessica, Hardiman Dudley, Atira, Niwa-Kawakita, Michiko, Page, Grier P., Giovannini, Marco, Aronow, Bruce J., Cripe, Timothy P., Ratner, Nancy

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Insertional mutagenesis identifies a STAT3/Arid1b/β-catenin pathway driving neurofibroma initiation Autor Wu, Jianqiang, Keng, Vincent, Patmore, Deanna M., Kendall, Jed K., Patel, Ami V., Jousma, Edwin, Jessen, Walter J., Choi, Kwangmin, Tschida, Barbara R., Silverstein, Kevin A. T., Fan, Danhua, Schwartz, Eric B., Fuchs, James R., Zou, Yuanshu, Kim, Mi-Ok, Dombi, Eva, Levy, David E., Huang, Gang, Cancelas, Jose A., Stemmer-Rachamimov, Anat O., Spinner, Robert J., Largaespada, David A., Ratner, Nancy

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