Search Results - Joshua J. Oaks

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  1. 1
    Regulation of PP2A by Sphingolipid Metabolism and Signaling

    Regulation of PP2A by Sphingolipid Metabolism and Signaling by Joshua J. Oaks, Besim Öğretmen

    Published 2015
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  2. 2
    The concerted roles of FANCM and Rad52 in the protection of common fragile sites

    The concerted roles of FANCM and Rad52 in the protection of common fragile sites by Hailong Wang, Shibo Li, Joshua J. Oaks, Jianping Ren, Lei Li, Xiaohua Wu

    Published 2018
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  3. 3
    The NMR‐based characterization of the FTY720‐SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET‐PP2A interaction

    The NMR‐based characterization of the FTY720‐SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET‐PP2A interaction by Ryan De Palma, Stuart Parnham, Yitong Li, Joshua J. Oaks, Yuri K. Peterson, Zdzisław M. Szulc, Braden M. Roth, Yongna Xing, Besim Öğretmen

    Published 2019
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  4. 4
    Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation

    Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation by Shanmugam Panneer Selvam, Ryan De Palma, Joshua J. Oaks, Natalia Oleinik, Yuri K. Peterson, Robert V. Stahelin, Emmanuel Skordalakes, Suriyan Ponnusamy, Elizabeth Garrett‐Mayer, Charles D. Smith, Besim Öğretmen

    Published 2015
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  5. 5
    Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

    Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia by Houda Alachkar, Ramasamy Santhanam, Jason G. Harb, David Lucas, Joshua J. Oaks, Christopher Hickey, Pan Li, A. Douglas Kinghorn, Michael A. Caligiuri, Danilo Perrotti, John C. Byrd, Ramiro Garzon, Michael R. Grever, Guido Marcucci

    Published 2013
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  6. 6
    Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis

    Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis by Sahar A. Saddoughi, Salih Gencer, Yuri K. Peterson, Katherine E. Ward, Archana Mukhopadhyay, Joshua J. Oaks, Jacek Bielawski, Zdzisław M. Szulc, Raquela J. Thomas, Shanmugam Panneer Selvam, Can E. Senkal, Elizabeth Garrett‐Mayer, Ryan De Palma, Dzmitry Fedarovich, Angen Liu, Amyn A. Habib, Robert V. Stahelin, Danilo Perrotti, Besim Öğretmen

    Published 2012
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  7. 7
    FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia

    FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia by Paolo Neviani, Ramasamy Santhanam, Joshua J. Oaks, Anna M. Eiring, Mario Notari, Bradley W. Blaser, Shujun Liu, Rossana Trotta, Natarajan Muthusamy, Carlo Gambacorti‐Passerini, Brian J. Druker, Jorge E. Cortés, Guido Marcucci, Ching-Shih Chen, Nicole M. Verrills, Denis‐Claude Roy, Michael A. Caligiuri, Clara D. Bloomfield, John C. Byrd, Danilo Perrotti

    Published 2007
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  8. 8
    Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A

    Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A by Arelis Salas, Suriyan Ponnusamy, Can E. Senkal, Marisa Meyers‐Needham, Shanmugam Panneer Selvam, Sahar A. Saddoughi, Elif Apohan, R. David Sentelle, Charles D. Smith, Christopher Gault, Lina M. Obeid, Hesham M. El‐Shewy, Joshua J. Oaks, Ramasamy Santhanam, Guido Marcucci, Yusuf Baran, Sandeep Mahajan, Daniel Fernandes, Robert K. Stuart, Danilo Perrotti, Besim Öğretmen

    Published 2011
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  9. 9
    Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias

    Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias by Christopher J. Walker, Joshua J. Oaks, Ramasamy Santhanam, Paolo Neviani, Jason G. Harb, Gregory Ferenchak, Justin J. Ellis, Yosef Landesman, Ann‐Kathrin Eisfeld, N. Gabrail, C. Smith, Michael A. Caligiuri, Peter Hokland, Denis‐Claude Roy, Alistair Reid, Dragana Milojković, John M. Goldman, Jane F. Apperley, Ramiro Garzon, Guido Marcucci, Sharon Shacham, Michael Kauffman, Danilo Perrotti

    Published 2013
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  10. 10
    miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts

    miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts by Anna M. Eiring, Jason G. Harb, Paolo Neviani, Christopher Garton, Joshua J. Oaks, Riccardo Spizzo, Shujun Liu, Sebastian Schwind, Ramasamy Santhanam, Christopher Hickey, Heiko Becker, Jason C. Chandler, Raul Andino, Jorge E. Cortés, Peter Hokland, Claudia S. Huettner, Ravi Bhatia, Denis Roy, Stephen A. Liebhaber, Michael A. Caligiuri, Guido Marcucci, Ramiro Garzon, Carlo M. Croce, George A. Calin, Danilo Perrotti

    Published 2010
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  11. 11
    Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies

    Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignancies by Joshua J. Oaks, Ramasamy Santhanam, Christopher J. Walker, Steve Roof, Jason G. Harb, Greg Ferenchak, Ann-Kathrin Eisfeld, James R. Van Brocklyn, Roger Briesewitz, Sahar A. Saddoughi, Kyosuke Nagata, Robert Bittman, Michael A. Caligiuri, Omar Abdel‐Wahab, Ross L. Levine, Ralph B. Arlinghaus, Alfonso Quintás‐Cardama, John M. Goldman, Jane F. Apperley, Alistair Reid, Dragana Milojković, Mark T. Ziolo, Guido Marcucci, Besim Öğretmen, Paolo Neviani, Danilo Perrotti

    Published 2013
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  12. 12
    PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells

    PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells by Paolo Neviani, Jason G. Harb, Joshua J. Oaks, Ramasamy Santhanam, Christopher J. Walker, Justin J. Ellis, Gregory Ferenchak, Adrienne M. Dorrance, Carolyn Paisie, Anna M. Eiring, Yihui Ma, Hsiaoyin Mao, Bin Zhang, Mark Wunderlich, Philippa C. May, Chaode Sun, Sahar A. Saddoughi, Jacek Bielawski, William Blum, Rebecca B. Klisovic, Janelle A. Solt, John C. Byrd, Stefano Volinia, Jorge E. Cortés, Claudia S. Huettner, Steffen Koschmieder, Tessa L. Holyoake, Steven M. Devine, Michael A. Caligiuri, Carlo M. Croce, Ramiro Garzon, Besim Öğretmen, Ralph B. Arlinghaus, Ching-Shih Chen, Robert Bittman, Peter Hokland, Denis-Claude Roy, Dragana Milojković, Jane F. Apperley, John M. Goldman, Alistair Reid, James C. Mulloy, Ravi Bhatia, Guido Marcucci, Danilo Perrotti

    Published 2013
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