Výsledky vyhledávání - Joshi, Sachindra

MicroRNAs-control of essential genes: Implications for pulmonary vascular disease Autor Joshi, Sachindra R., McLendon, Jared M., Comer, Brian S., Gerthoffer, William T.

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MicroRNA Regulation of Smooth Muscle Phenotype Autor Joshi, Sachindra R., Comer, Brian S., McLendon, Jared M., Gerthoffer, William T.

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Nucleosome dynamics: HMGB1 relaxes canonical nucleosome structure to facilitate estrogen receptor binding Autor Joshi, Sachindra R., Sarpong, Yaw C., Peterson, Ronald C., Scovell, William M.

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Therapeutic Approaches for Treating Pulmonary Arterial Hypertension by Correcting Imbalanced TGF-β Superfamily Signaling Autor Andre, Patrick, Joshi, Sachindra R., Briscoe, Steven D., Alexander, Mark J., Li, Gang, Kumar, Ravindra

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MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension. Autor Joshi, Sachindra Raj, Dhagia, Vidhi, Gairhe, Salina, Edwards, John G., McMurtry, Ivan F., Gupte, Sachin A.

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Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133(+) progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypert... Autor Chettimada, Sukrutha, Joshi, Sachindra Raj, Alzoubi, Abdallah, Gebb, Sarah A., McMurtry, Ivan F., Gupte, Rakhee, Gupte, Sachin A.

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Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition... Autor Chettimada, Sukrutha, Joshi, Sachindra Raj, Dhagia, Vidhi, Aiezza, Alessandro, Lincoln, Thomas M., Gupte, Rakhee, Miano, Joseph M., Gupte, Sachin A.

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Cyp2c44 gene disruption is associated with increased hematopoietic stem cells: implication in chronic hypoxia-induced pulmonary hypertension Autor Hashimoto, Ryota, Joshi, Sachindra Raj, Jiang, Houli, Capdevila, Jorge H., McMurtry, Ivan F., Laniado Schwartzman, Michal, Gupte, Sachin A.

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20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition Autor Lakhkar, Anand, Dhagia, Vidhi, Joshi, Sachindra Raj, Gotlinger, Katherine, Patel, Dhara, Sun, Dong, Wolin, Michael S., Schwartzman, Michal L., Gupte, Sachin A.

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Sphingosine-1-phosphate is involved in the occlusive arteriopathy of pulmonary arterial hypertension Autor Gairhe, Salina, Joshi, Sachindra R., Bastola, Mrigendra M., McLendon, Jared M., Oka, Masahiko, Fagan, Karen A., McMurtry, Ivan F.

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Aneurysm-type plexiform lesions form in supernumerary arteries in pulmonary arterial hypertension: potential therapeutic implications Autor Oshima, Kaori, Crockett, Edward S., Joshi, Sachindra R., McLendon, Jared M., Matsumoto, Yuri, McMurtry, Ivan F., Abe, Kohtaro, Oka, Masahiko

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Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity Autor Mitry, Maria A., Laurent, Dimitri, Keith, Britny L., Sira, Elizabeth, Eisenberg, Carol A., Eisenberg, Leonard M., Joshi, Sachindra, Gupte, Sachin, Edwards, John G.

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Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension Autor McLendon, Jared M., Joshi, Sachindra R., Sparks, Jeff, Matar, Majed, Fewell, Jason G., Abe, Kohtaro, Oka, Masahiko, McMurtry, Ivan F., Gerthoffer, William T.

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Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension Autor Hashimoto, Ryota, Lanier, Gregg M., Dhagia, Vidhi, Joshi, Sachindra R., Jordan, Allan, Waddell, Ian, Tuder, Rubin, Stenmark, Kurt R., Wolin, Michael S., McMurtry, Ivan F., Gupte, Sachin A.

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Involvement of gap junctions between smooth muscle cells in sustained hypoxic pulmonary vasoconstriction development: a potential role for 15-HETE and 20-HETE Autor Kizub, Igor V., Lakhkar, Anand, Dhagia, Vidhi, Joshi, Sachindra R., Jiang, Houli, Wolin, Michael S., Falck, John R., Koduru, Sreenivasulu Reddy, Errabelli, Ramu, Jacobs, Elizabeth R., Schwartzman, Michal L., Gupte, Sachin A.

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Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice Autor Joshi, Sachindra Raj, Lakhkar, Anand, Dhagia, Vidhi, Zias, Ariadne L., Soldatos, Vasiliki, Oshima, Kaori, Jiang, Houli, Gotlinger, Katherine, Capdevila, Jorge H., Schwartzman, Michal L., McMurtry, Ivan F., Gupte, Sachin A.

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Elevated 20-HETE in Metabolic Syndrome Regulates Arterial Stiffness and Systolic Hypertension via MMP12 Activation Autor Soler, Amanda, Hunter, Ian, Joseph, Gregory, Hutcheson, Rebecca, Hutcheson, Brenda, Yang, Jenny, Zhang, Frank Fan, Joshi, Sachindra Raj, Bradford, Chastity, Gotlinger, Katherine H., Maniyar, Rachana, Falck, John R., Proctor, Spencer, Schwartzman, Michal Laniado, Gupte, Sachin A., Rocic, Petra

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Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methyl... Autor Joshi, Sachindra Raj, Kitagawa, Atsushi, Jacob, Christina, Hashimoto, Ryota, Dhagia, Vidhi, Ramesh, Amrit, Zheng, Connie, Zhang, Hui, Jordan, Allan, Waddell, Ian, Leopold, Jane, Hu, Cheng-Jun, McMurtry, Ivan F., D’Alessandro, Angelo, Stenmark, Kurt R., Gupte, Sachin A.

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ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension Autor Yung, Lai-Ming, Yang, Peiran, Joshi, Sachindra, Augur, Zachary M., Kim, Stephanie S. J., Bocobo, Geoffrey A., Dinter, Teresa, Troncone, Luca, Chen, Po-Sheng, McNeil, Megan E., Southwood, Mark, de Frias, Sergio Poli, Knopf, John, Rosas, Ivan O., Sako, Dianne, Pearsall, R. Scott, Quisel, John D., Li, Gang, Kumar, Ravindra, Yu, Paul B.

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Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension Autor Joshi, Sachindra R., Liu, Jun, Bloom, Troy, Karaca Atabay, Elif, Kuo, Tzu-Hsing, Lee, Michael, Belcheva, Elitza, Spaits, Matthew, Grenha, Rosa, Maguire, Michelle C., Frost, Jeffrey L., Wang, Kathryn, Briscoe, Steven D., Alexander, Mark J., Herrin, Brantley R., Castonguay, Roselyne, Pearsall, R. Scott, Andre, Patrick, Yu, Paul B., Kumar, Ravindra, Li, Gang

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