Ngā hua rapu - Joseph R. Mazzulli

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  1. 1
    Is Parkinson’s disease a lysosomal disorder?

    Is Parkinson’s disease a lysosomal disorder? mā Andrés D. Klein, Joseph R. Mazzulli

    I whakaputaina 2018
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  2. 2
    Molecular mechanisms of α-synuclein and GBA1 in Parkinson’s disease

    Molecular mechanisms of α-synuclein and GBA1 in Parkinson’s disease mā Iva Stojkovska, Dimitri Krainc, Joseph R. Mazzulli

    I whakaputaina 2017
    Whiwhi kuputuhi katoa
    Revisão
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  3. 3
    Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease

    Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease mā Caleb Pitcairn, Willayat Yousuf Wani, Joseph R. Mazzulli

    I whakaputaina 2018
    Whiwhi kuputuhi katoa
    Revisão
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  4. 4
    Characterization of Hydrophobic Residue Requirements for α-Synuclein Fibrillization

    Characterization of Hydrophobic Residue Requirements for α-Synuclein Fibrillization mā Elisa A. Waxman, Joseph R. Mazzulli, Benoit I. Giasson

    I whakaputaina 2009
    Whiwhi kuputuhi katoa
    Artigo
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  5. 5
    Cellular Oligomerization of α-Synuclein Is Determined by the Interaction of Oxidized Catechols with a C-terminal Sequence

    Cellular Oligomerization of α-Synuclein Is Determined by the Interaction of Oxidized Catechols with a C-terminal Sequence mā Joseph R. Mazzulli, Maria Armakola, Michelle Dumoulin, Ioannis Parastatidis, Harry Ischiropoulos

    I whakaputaina 2007
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  6. 6
    α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models

    α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models mā Joseph R. Mazzulli, Friederike Zunke, Ole Isacson, Lorenz Studer, Dimitri Krainc

    I whakaputaina 2016
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  7. 7
    Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity

    Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity mā Marija Usenovic, Emilie Tresse, Joseph R. Mazzulli, J. Paul Taylor, Dimitri Krainc

    I whakaputaina 2012
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  8. 8
    AAV9/MFSD8 gene therapy is effective in preclinical models of neuronal ceroid lipofuscinosis type 7 disease

    AAV9/MFSD8 gene therapy is effective in preclinical models of neuronal ceroid lipofuscinosis type 7 disease mā Xin Chen, Thomas Dong, Yuhui Hu, Frances C. Shaffo, Nandkishore R. Belur, Joseph R. Mazzulli, Steven J. Gray

    I whakaputaina 2022
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  9. 9
    Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking

    Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking mā Iva Stojkovska, Willayat Yousuf Wani, Friederike Zunke, Nandkishore R. Belur, Egor Pavlenko, Nkatha Mwenda, Karan Sharma, Laetitia Francelle, Joseph R. Mazzulli

    I whakaputaina 2021
    Whiwhi kuputuhi katoa
    Artigo
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  10. 10
    Cytosolic Catechols Inhibit α-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates

    Cytosolic Catechols Inhibit α-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates mā Joseph R. Mazzulli, Amanda J. Mishizen, Benoit I. Giasson, David R. Lynch, Steven Thomas, Akira Nakashima, Toshiharu Nagatsu, Akira Ota, Harry Ischiropoulos

    I whakaputaina 2006
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  11. 11
    Distinct Region-Specific α-Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration

    Distinct Region-Specific α-Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration mā Elpida Tsika, Maria Moysidou, Jing Guo, Mimi Cushman, Patrick J. Gannon, Raphael Sandaltzopoulos, Benoit I. Giasson, Dimitri Krainc, Harry Ischiropoulos, Joseph R. Mazzulli

    I whakaputaina 2010
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  12. 12
    Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2

    Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2 mā Friederike Zunke, Lisa Andresen, Sophia Wesseler, Johann Groth, Philipp Arnold, Michelle Rothaug, Joseph R. Mazzulli, Dimitri Krainc, Judith Blanz, Paul Säftig, Michael Schwake

    I whakaputaina 2016
    Whiwhi kuputuhi katoa
    Artigo
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  13. 13
    Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide

    Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide mā Friederike Zunke, Alexandra C. Moise, Nandkishore R. Belur, Eilrayna Gelyana, Iva Stojkovska, Haris Dzaferbegovic, Nicholas Toker, Sohee Jeon, Kristina Fredriksen, Joseph R. Mazzulli

    I whakaputaina 2017
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  14. 14
    Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

    Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway mā Hyunkyung Jeong, Dena E. Cohen, Libin Cui, Andrea Supinski, Jeffrey N. Savas, Joseph R. Mazzulli, John R. Yates, Laura Bordone, Leonard Guarente, Dimitri Krainc

    I whakaputaina 2011
    Whiwhi kuputuhi katoa
    Artigo
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  15. 15
    Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

    Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies mā Joseph R. Mazzulli, You-Hai Xu, Ying Sun, Adam L. Knight, Pamela J. McLean, Guy A. Caldwell, Ellen Sidransky, Gregory A. Grabowski, Dimitri Krainc

    I whakaputaina 2011
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  16. 16
    Activation of -Glucocerebrosidase Reduces Pathological -Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons

    Activation of -Glucocerebrosidase Reduces Pathological -Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons mā Joseph R. Mazzulli, Friederike Zunke, Taiji Tsunemi, Nicholas Toker, Sohee Jeon, Lena F. Burbulla, Samarjit Patnaik, Ellen Sidransky, Juan Marugán, Carolyn M. Sue, Dimitri Krainc

    I whakaputaina 2016
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  17. 17
    Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation

    Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation mā Hyunkyung Jeong, Florian Then, Thomas J. Melia, Joseph R. Mazzulli, Libin Cui, Jeffrey N. Savas, Cindy Voisine, Paolo Paganetti, Naoko Tanese, Anne C. Hart, Ai Yamamoto, Dimitri Krainc

    I whakaputaina 2009
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  18. 18
    Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models

    Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models mā Alice Drobny, Fanni Annamária Boros, Denise Balta, Susy Prieto Huarcaya, Deniz Caylioglu, Niyeti Qazi, Julia Vandrey, Yanni Schneider, Jan Philipp Dobert, Caleb Pitcairn, Joseph R. Mazzulli, Friederike Zunke

    I whakaputaina 2023
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  19. 19
    Increased Lysosomal Exocytosis Induced by Lysosomal Ca<sup>2+</sup> Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity

    Increased Lysosomal Exocytosis Induced by Lysosomal Ca<sup>2+</sup> Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity mā Taiji Tsunemi, Tamara Perez‐Rosello, Yuta Ishiguro, Asako Yoroisaka, Sohee Jeon, Kana Hamada, Malini Rammonhan, Yvette C. Wong, Zhong Xie, Wado Akamatsu, Joseph R. Mazzulli, D. James Surmeier, Nobutaka Hattori, Dimitri Krainc

    I whakaputaina 2019
    Whiwhi kuputuhi katoa
    Artigo
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  20. 20
    Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation

    Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation mā Sun Young Chung, Sarah Kishinevsky, Joseph R. Mazzulli, John J. Graziotto, Ana Mrejeru, Eugene V. Mosharov, Lesly Puspita, Parvin Valiulahi, David Sulzer, Teresa A. Milner, Tony Taldone, Dimitri Krainc, Lorenz Studer, Jae-won Shim

    I whakaputaina 2016
    Whiwhi kuputuhi katoa
    Artigo
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