Torthaí cuardaigh - Joseph R. Mazzulli
- 1 - 20 toradh as 32 á dtaispeáint
- Téigh chuig an gcéad leathanach eile
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1
Is Parkinson’s disease a lysosomal disorder? de réir Andrés D. Klein, Joseph R. Mazzulli
Foilsithe / Cruthaithe 2018Artigo -
2
Molecular mechanisms of α-synuclein and GBA1 in Parkinson’s disease de réir Iva Stojkovska, Dimitri Krainc, Joseph R. Mazzulli
Foilsithe / Cruthaithe 2017Revisão -
3
Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease de réir Caleb Pitcairn, Willayat Yousuf Wani, Joseph R. Mazzulli
Foilsithe / Cruthaithe 2018Revisão -
4
Characterization of Hydrophobic Residue Requirements for α-Synuclein Fibrillization de réir Elisa A. Waxman, Joseph R. Mazzulli, Benoit I. Giasson
Foilsithe / Cruthaithe 2009Artigo -
5
Cellular Oligomerization of α-Synuclein Is Determined by the Interaction of Oxidized Catechols with a C-terminal Sequence de réir Joseph R. Mazzulli, Maria Armakola, Michelle Dumoulin, Ioannis Parastatidis, Harry Ischiropoulos
Foilsithe / Cruthaithe 2007Artigo -
6
α-Synuclein–induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models de réir Joseph R. Mazzulli, Friederike Zunke, Ole Isacson, Lorenz Studer, Dimitri Krainc
Foilsithe / Cruthaithe 2016Artigo -
7
Deficiency of ATP13A2 Leads to Lysosomal Dysfunction, α-Synuclein Accumulation, and Neurotoxicity de réir Marija Usenovic, Emilie Tresse, Joseph R. Mazzulli, J. Paul Taylor, Dimitri Krainc
Foilsithe / Cruthaithe 2012Artigo -
8
AAV9/MFSD8 gene therapy is effective in preclinical models of neuronal ceroid lipofuscinosis type 7 disease de réir Xin Chen, Thomas Dong, Yuhui Hu, Frances C. Shaffo, Nandkishore R. Belur, Joseph R. Mazzulli, Steven J. Gray
Foilsithe / Cruthaithe 2022Artigo -
9
Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking de réir Iva Stojkovska, Willayat Yousuf Wani, Friederike Zunke, Nandkishore R. Belur, Egor Pavlenko, Nkatha Mwenda, Karan Sharma, Laetitia Francelle, Joseph R. Mazzulli
Foilsithe / Cruthaithe 2021Artigo -
10
Cytosolic Catechols Inhibit α-Synuclein Aggregation and Facilitate the Formation of Intracellular Soluble Oligomeric Intermediates de réir Joseph R. Mazzulli, Amanda J. Mishizen, Benoit I. Giasson, David R. Lynch, Steven Thomas, Akira Nakashima, Toshiharu Nagatsu, Akira Ota, Harry Ischiropoulos
Foilsithe / Cruthaithe 2006Artigo -
11
Distinct Region-Specific α-Synuclein Oligomers in A53T Transgenic Mice: Implications for Neurodegeneration de réir Elpida Tsika, Maria Moysidou, Jing Guo, Mimi Cushman, Patrick J. Gannon, Raphael Sandaltzopoulos, Benoit I. Giasson, Dimitri Krainc, Harry Ischiropoulos, Joseph R. Mazzulli
Foilsithe / Cruthaithe 2010Artigo -
12
Characterization of the complex formed by β-glucocerebrosidase and the lysosomal integral membrane protein type-2 de réir Friederike Zunke, Lisa Andresen, Sophia Wesseler, Johann Groth, Philipp Arnold, Michelle Rothaug, Joseph R. Mazzulli, Dimitri Krainc, Judith Blanz, Paul Säftig, Michael Schwake
Foilsithe / Cruthaithe 2016Artigo -
13
Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide de réir Friederike Zunke, Alexandra C. Moise, Nandkishore R. Belur, Eilrayna Gelyana, Iva Stojkovska, Haris Dzaferbegovic, Nicholas Toker, Sohee Jeon, Kristina Fredriksen, Joseph R. Mazzulli
Foilsithe / Cruthaithe 2017Artigo -
14
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway de réir Hyunkyung Jeong, Dena E. Cohen, Libin Cui, Andrea Supinski, Jeffrey N. Savas, Joseph R. Mazzulli, John R. Yates, Laura Bordone, Leonard Guarente, Dimitri Krainc
Foilsithe / Cruthaithe 2011Artigo -
15
Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies de réir Joseph R. Mazzulli, You-Hai Xu, Ying Sun, Adam L. Knight, Pamela J. McLean, Guy A. Caldwell, Ellen Sidransky, Gregory A. Grabowski, Dimitri Krainc
Foilsithe / Cruthaithe 2011Artigo -
16
Activation of -Glucocerebrosidase Reduces Pathological -Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons de réir Joseph R. Mazzulli, Friederike Zunke, Taiji Tsunemi, Nicholas Toker, Sohee Jeon, Lena F. Burbulla, Samarjit Patnaik, Ellen Sidransky, Juan Marugán, Carolyn M. Sue, Dimitri Krainc
Foilsithe / Cruthaithe 2016Artigo -
17
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation de réir Hyunkyung Jeong, Florian Then, Thomas J. Melia, Joseph R. Mazzulli, Libin Cui, Jeffrey N. Savas, Cindy Voisine, Paolo Paganetti, Naoko Tanese, Anne C. Hart, Ai Yamamoto, Dimitri Krainc
Foilsithe / Cruthaithe 2009Artigo -
18
Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models de réir Alice Drobny, Fanni Annamária Boros, Denise Balta, Susy Prieto Huarcaya, Deniz Caylioglu, Niyeti Qazi, Julia Vandrey, Yanni Schneider, Jan Philipp Dobert, Caleb Pitcairn, Joseph R. Mazzulli, Friederike Zunke
Foilsithe / Cruthaithe 2023Artigo -
19
Increased Lysosomal Exocytosis Induced by Lysosomal Ca<sup>2+</sup> Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity de réir Taiji Tsunemi, Tamara Perez‐Rosello, Yuta Ishiguro, Asako Yoroisaka, Sohee Jeon, Kana Hamada, Malini Rammonhan, Yvette C. Wong, Zhong Xie, Wado Akamatsu, Joseph R. Mazzulli, D. James Surmeier, Nobutaka Hattori, Dimitri Krainc
Foilsithe / Cruthaithe 2019Artigo -
20
Parkin and PINK1 Patient iPSC-Derived Midbrain Dopamine Neurons Exhibit Mitochondrial Dysfunction and α-Synuclein Accumulation de réir Sun Young Chung, Sarah Kishinevsky, Joseph R. Mazzulli, John J. Graziotto, Ana Mrejeru, Eugene V. Mosharov, Lesly Puspita, Parvin Valiulahi, David Sulzer, Teresa A. Milner, Tony Taldone, Dimitri Krainc, Lorenz Studer, Jae-won Shim
Foilsithe / Cruthaithe 2016Artigo
Uirlisí cuardaigh:
Ábhair a bhaineann le hábhar
Biology
Medicine
Disease
Cell biology
Parkinson's disease
Biochemistry
Gene
Neuroscience
Alpha-synuclein
Internal medicine
Pathology
Chemistry
Neurodegeneration
Genetics
Apoptosis
Dopamine
Enzyme
Autophagy
Protein aggregation
Dopaminergic
Synucleinopathies
Embryonic stem cell
Induced pluripotent stem cell
Bioinformatics
Fibril
Glucocerebrosidase
Intracellular
Mutant
Biophysics
Central nervous system