Rezultati - Joseph M. Replogle
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Mapping Transcriptomic Vector Fields of Single Cells od Xiaojie Qiu, Yan Zhang, Shayan Hosseinzadeh, Dian Yang, Angela N. Pogson, Li Wang, Matt Shurtleff, Ruoshi Yuan, Xu Song, Yi-An Ma, Joseph M. Replogle, Spyros Darmanis, İvet Bahar, Jianhua Xing, Jonathan S. Weissman
Izdano 2019Pré-impressão -
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GIGYF2 and 4EHP Inhibit Translation Initiation of Defective Messenger RNAs to Assist Ribosome-Associated Quality Control od Kelsey Hickey, Kimberley Dickson, J. Zachery Cogan, Joseph M. Replogle, Michael Schoof, Karole N. D’Orazio, Niladri K. Sinha, Jeffrey A. Hussmann, Marco Jost, Adam Frost, Rachel Green, Jonathan S. Weissman, Kamena K. Kostova
Izdano 2020Artigo -
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Interindividual variation in human T regulatory cells od Alessandra M. Ferraro, Anna Morena D’Alise, Towfique Raj, Natasha Asinovski, Roxanne Phillips, Ayla Ergün, Joseph M. Replogle, Angelina Bernier, Lori M. Laffel, Barbara E. Stranger, Philip L. De Jager, Diane Mathis, Christophe Benoist
Izdano 2014Artigo -
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A <scp><i>TREM</i></scp><i>1</i> variant alters the accumulation of Alzheimer‐related amyloid pathology od Joseph M. Replogle, Gail Chan, Charles C. White, Towfique Raj, Phoebe A. Winn, Denis A. Evans, Reisa A. Sperling, Lori B. Chibnik, Elizabeth M. Bradshaw, Julie A. Schneider, David A. Bennett, Philip L. De Jager
Izdano 2014Artigo -
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CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility od Towfique Raj, Kenneth J. Ryan, Joseph M. Replogle, Lori B. Chibnik, Laura Rosenkrantz, Acacia Tsz So Tang, Katherine Rothamel, Barbara E. Stranger, David A. Bennett, Denis A. Evans, Philip L. De Jager, Elizabeth M. Bradshaw
Izdano 2013Revisão -
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MTCH2 is a mitochondrial outer membrane protein insertase od Alina Guna, Taylor A. Stevens, Alison J. Inglis, Joseph M. Replogle, Theodore K. Esantsi, Gayathri Muthukumar, Kelly Shaffer, Maxine L. Wang, Angela N. Pogson, Jeff Jones, Brett Lomenick, Tsui‐Fen Chou, Jonathan S. Weissman, R.M. Voorhees
Izdano 2022Artigo -
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Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning od Luke W. Koblan, Mandana Arbab, Max W. Shen, Jeffrey A. Hussmann, Andrew V. Anzalone, Jordan L. Doman, Gregory A. Newby, Dian Yang, Beverly Mok, Joseph M. Replogle, Albert Xu, Tyler A. Sisley, Jonathan S. Weissman, Britt Adamson, David R. Liu
Izdano 2021Artigo -
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CD33 modulates TREM2: convergence of Alzheimer loci od Gail Chan, Charles C. White, Phoebe A. Winn, Maria Cimpean, Joseph M. Replogle, Laura Glick, Nicole Cuerdon, Katie J. Ryan, Keith A. Johnson, Julie A. Schneider, David A. Bennett, Lori B. Chibnik, Reisa A. Sperling, Elizabeth M. Bradshaw, Philip L. De Jager
Izdano 2015Artigo -
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Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing od Joseph M. Replogle, Thomas M. Norman, Albert Xu, Jeffrey A. Hussmann, Jin Chen, J. Zachery Cogan, Elliott J. Meer, Jessica M. Terry, Daniel P. Riordan, Niranjan Srinivas, Ian T. Fiddes, Joseph G. Arthur, Luigi J. Alvarado, Katherine A. Pfeiffer, Tarjei S. Mikkelsen, Jonathan S. Weissman, Britt Adamson
Izdano 2020Artigo -
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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq od Joseph M. Replogle, Reuben A. Saunders, Angela N. Pogson, Jeffrey A. Hussmann, Alexander LeNail, Alina Guna, Lauren G. Mascibroda, Eric J. Wagner, Karen Adelman, Gila Lithwick‐Yanai, Nika Iremadze, Florian C. Oberstrass, Doron Lipson, Jessica L. Bonnar, Marco Jost, Thomas M. Norman, Jonathan S. Weissman
Izdano 2022Artigo -
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Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus od James Bentham, David Morris, Deborah S. Cunninghame Graham, Christopher L. Pinder, Philip Tombleson, Timothy W. Behrens, Javier Martı́n, Benjamin P. Fairfax, Julian C. Knight, Lingyan Chen, Joseph M. Replogle, Ann-Christine Syvänen, Lars Rönnblom, Robert Graham, Joan Wither, John D. Rioux, Marta E. Alarcón‐Riquelme, Timothy J. Vyse
Izdano 2015Artigo -
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Systematic functional interrogation of SARS-CoV-2 host factors using Perturb-seq od Sara Sunshine, Andreas S. Puschnik, Joseph M. Replogle, Matthew T. Laurie, Jamin Liu, Beth Shoshana Zha, James K. Nuñez, Janie R. Byrum, Aidan H. McMorrow, Matthew B. Frieman, Juliane Winkler, Xiaojie Qiu, Oren S. Rosenberg, Manuel D. Leonetti, Chun Ye, Jonathan S. Weissman, Joseph L. DeRisi, Marco Y. Hein
Izdano 2023Artigo -
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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors od Joseph M. Replogle, Jessica L. Bonnar, Angela N. Pogson, Christina R. Liem, Nolan K Maier, Yufang Ding, Baylee J. Russell, Wang Xing-ren, Kun Leng, Alina Guna, Thomas M. Norman, Ryan A. Pak, Daniel M. Ramos, Michael E. Ward, Luke A. Gilbert, Martin Kampmann, Jonathan S. Weissman, Marco Jost
Izdano 2022Artigo -
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A pharmacogenetic study implicates <scp><i>SLC9a9</i></scp> in multiple sclerosis disease activity od Federica Esposito, Melissa Sorosina, Linda Ottoboni, Elaine T. Lim, Joseph M. Replogle, Towfique Raj, Paola Brambilla, Giuseppe Liberatore, Clara Guaschino, Marzia Romeo, Thomas Pertel, James Stankiewicz, Vittorio Martinelli, Mariaemma Rodegher, Howard L. Weiner, David Brassat, Christophe Benoist, Nikolaos A. Patsopoulos, Gıancarlo Comı, Wassim Elyaman, Filippo Martinelli Boneschi, Philip L. De Jager
Izdano 2015Artigo -
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A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants od Katie J. Ryan, Charles C. White, K R Patel, Jishu Xu, Marta Olah, Joseph M. Replogle, Michael Frangieh, Maria Cimpean, Phoebe A. Winn, Allison McHenry, Belinda J. Kaskow, Gail Chan, Nicole Cuerdon, David A. Bennett, Justin D. Boyd, Jaime Imitola, Wassim Elyaman, Philip L. De Jager, Elizabeth M. Bradshaw
Izdano 2017Artigo -
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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing od James K. Nuñez, Jin Chen, Greg C. Pommier, J. Zachery Cogan, Joseph M. Replogle, Carmen Adriaens, Gokul N. Ramadoss, Quanming Shi, King L. Hung, Avi J. Samelson, Angela N. Pogson, James Y.S. Kim, Amanda G. Chung, Manuel D. Leonetti, Howard Y. Chang, Martin Kampmann, B Bernstein, Volker Hovestadt, Luke A. Gilbert, Jonathan S. Weissman
Izdano 2021Artigo -
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Mapping transcriptomic vector fields of single cells od Xiaojie Qiu, Yan Zhang, Jorge D. Martin-Rufino, Chen Weng, Shayan Hosseinzadeh, Dian Yang, Angela N. Pogson, Marco Y. Hein, Kyung Hoi Min, Li Wang, Emanuelle I. Grody, Matthew J. Shurtleff, Ruoshi Yuan, Song Xu, Yi-An Ma, Joseph M. Replogle, Eric S. Lander, Spyros Darmanis, İvet Bahar, Vijay G. Sankaran, Jianhua Xing, Jonathan S. Weissman
Izdano 2022Artigo
Iskalna orodja:
Sorodne teme
Biology
Genetics
Gene
Computational biology
Disease
Medicine
Allele
Computer science
CRISPR
Cell
Cell biology
Genotype
Immunology
Pathology
Phenotype
Gene expression
Genome-wide association study
Inflammation
Locus (genetics)
Single-nucleotide polymorphism
Cas9
DNA
DNA methylation
Epigenetics
Evolutionary biology
Expression quantitative trait loci
Genome
Genome editing
Immune system
Internal medicine