Výsledky vyhledávání - Josep V. Forment

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  1. 1
    A flow cytometry–based method to simplify the analysis and quantification of protein association to chromatin in mammalian cells

    A flow cytometry–based method to simplify the analysis and quantification of protein association to chromatin in mammalian cells Autor Josep V. Forment, Stephen P. Jackson

    Vydáno 2015
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  2. 2
    A high‐throughput, flow cytometry‐based method to quantify DNA‐end resection in mammalian cells

    A high‐throughput, flow cytometry‐based method to quantify DNA‐end resection in mammalian cells Autor Josep V. Forment, Rachael Walker, Stephen P. Jackson

    Vydáno 2012
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  3. 3
    Structure-Specific DNA Endonuclease Mus81/Eme1 Generates DNA Damage Caused by Chk1 Inactivation

    Structure-Specific DNA Endonuclease Mus81/Eme1 Generates DNA Damage Caused by Chk1 Inactivation Autor Josep V. Forment, Melanie Blasius, Ilaria Guerini, Stephen P. Jackson

    Vydáno 2011
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  4. 4
    A meta-analysis of reversion mutations in BRCA genes identifies signatures of DNA end-joining repair mechanisms driving therapy resistance

    A meta-analysis of reversion mutations in BRCA genes identifies signatures of DNA end-joining repair mechanisms driving therapy resistance Autor Luis Tobalina, Joshua Armenia, Elsa Irving, Mark J. O’Connor, Josep V. Forment

    Vydáno 2020
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  5. 5
    A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1

    A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1 Autor Melanie Blasius, Josep V. Forment, Neha Thakkar, Sebastian Wagner, Chunaram Choudhary, Stephen P. Jackson

    Vydáno 2011
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  6. 6
    CDK targeting of NBS1 promotes DNA‐end resection, replication restart and homologous recombination

    CDK targeting of NBS1 promotes DNA‐end resection, replication restart and homologous recombination Autor Jacob Falck, Josep V. Forment, Julia Coates, Martin Mistrík, Jiří Lukáš, Jiří Bártek, Stephen P. Jackson

    Vydáno 2012
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  7. 7
    Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells

    Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells Autor Josep V. Forment, Mareike Herzog, Julia Coates, Tomasz Konopka, Bianca V. Gapp, Sebastian Nijman, David J. Adams, Thomas Keane, Stephen P. Jackson

    Vydáno 2016
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  8. 8
    Understanding tumour growth variability in patient-derived breast cancer xenograft models identifies early responders and biomarkers of resistance to PARP inhibition

    Understanding tumour growth variability in patient-derived breast cancer xenograft models identifies early responders and biomarkers of resistance to PARP inhibition Autor Mark J. O’Connor, Dimitrios Voulgarelis, Josep V. Forment, Andrea Herencia-Ropero, Dimitris Polychronopoulos, Andreas Bender, Violeta Serra, James Yates, Krishna C. Bulusu

    Vydáno 2024
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  9. 9
    Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

    Small-molecule–induced DNA damage identifies alternative DNA structures in human genes Autor Raphaël Rodriguez, Kyle M. Miller, Josep V. Forment, Charles R. Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalçe, Shankar Balasubramanian, Stephen P. Jackson

    Vydáno 2012
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  10. 10
    Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

    Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity Autor Ryotaro Nishi, Paul W.G. Wijnhoven, Carlos le Sage, Jorrit Tjeertes, Yaron Galanty, Josep V. Forment, Michael J. Clague, Sylvie Urbé, Stephen P. Jackson

    Vydáno 2014
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  11. 11
    CtIP tetramer assembly is required for DNA-end resection and repair

    CtIP tetramer assembly is required for DNA-end resection and repair Autor Owen R. Davies, Josep V. Forment, Meidai Sun, Rimma Belotserkovskaya, Julia Coates, Yaron Galanty, Mehmet Demir, Christopher Morton, Neil J. Rzechorzek, Stephen P. Jackson, Luca Pellegrini

    Vydáno 2015
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  12. 12
    Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress

    Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress Autor Rebecca L. Lloyd, Václav Urban, Francisco Muñoz‐Martínez, Iñigo Ayestaran, John C. Thomas, Christelle de Renty, Mark J. O’Connor, Josep V. Forment, Yaron Galanty, Stephen P. Jackson

    Vydáno 2021
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  13. 13
    Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions

    Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions Autor Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M. Foster, Francisco Martı́n, Kira Brüninghoff, Kathleen Cain, Wolfgang Dörner, María J. Cabello-Lobato, Josep V. Forment, Matthew J. Cliff, Igor Larrosa, Perdita E. Barran, Duncan L. Smith, Henning D. Mootz, Christine K. Schmidt

    Vydáno 2025
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  14. 14
    XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

    XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data Autor Roelof J.C. Kluin, Kristel Kemper, Thomas Kuilman, Julian R. de Ruiter, Vivek Iyer, Josep V. Forment, Paulien Cornelissen‐Steijger, Iris de Rink, Petra ter Brugge, Ji‐Ying Song, Sjoerd Klarenbeek, Ultan McDermott, Jos Jonkers, Arno Velds, David J. Adams, Daniel S. Peeper, Oscar Krijgsman

    Vydáno 2018
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  15. 15
    ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

    ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks Autor Gabriel Balmus, Domenic Pilger, Julia Coates, Mehmet Demir, Matylda Sczaniecka-Clift, Ana C. Barros, Michael Woods, Beiyuan Fu, Fengtang Yang, Elisabeth Chen, Matthias Ostermaier, Tatjana Stanković, Hannes Ponstingl, Mareike Herzog, Kosuke Yusa, Francisco Muñoz‐Martínez, Stephen T. Durant, Yaron Galanty, Petra Beli, David J. Adams, Allan Bradley, Emmanouil Metzakopian, Josep V. Forment, Stephen P. Jackson

    Vydáno 2019
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  16. 16
    Base editing screens define the genetic landscape of cancer drug resistance mechanisms

    Base editing screens define the genetic landscape of cancer drug resistance mechanisms Autor Matthew A. Coelho, Magdalena E. Strauß, Alex Watterson, Sarah Cooper, Shriram G. Bhosle, Giuditta Illuzzi, Emre Karakoç, Cansu Dinçer, Sara F. Vieira, Mamta Sharma, Marie Moullet, Daniela Conticelli, Jonas Koeppel, Katrina McCarten, Chiara M. Cattaneo, Vivien Veninga, Gabriele Picco, Leopold Parts, Josep V. Forment, Emile E. Voest, John C. Marioni, Andrew Bassett, Mathew J. Garnett

    Vydáno 2024
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  17. 17
    Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing

    Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing Autor Sandra Wimberger, Nina Akrap, Mike Firth, Johan Brengdahl, Susanna Engberg, Marie K. Schwinn, Michael R. Slater, Anders Lundin, Pei-Pei Hsieh, Songyuan Li, Silvia Cerboni, Jonathan Sumner, Burcu Bestas, Bastian Schiffthaler, Björn Magnusson, Silvio Di Castro, Preeti Iyer, Mohammad Bohlooly‐Y, Thomas Machleidt, Steve Rees, Ola Engkvist, Tyrell Norris, Elaine Cadogan, Josep V. Forment, Saša Šviković, Pınar Akçakaya, Amir Taheri‐Ghahfarokhi, Marcello Maresca

    Vydáno 2023
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  18. 18
    Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome

    Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome Autor Rebecca E. McIntyre, Pavithra L. Chavali, Ozama Ismail, Damian M. Carragher, Gabriela Sánchez-Andrade, Josep V. Forment, Beiyuan Fu, Martin Del Castillo Velasco‐Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang, Ramiro Ramírez‐Solis, Jeanne Estabel, Ferdia A. Gallagher, Darren W. Logan, Mark J. Arends, Stephen H. Tsang, Vinit B. Mahajan, Cheryl L. Scudamore, Jacqueline K. White, Stephen P. Jackson, Fanni Gergely, David J. Adams

    Vydáno 2012
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  19. 19
    H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours

    H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours Autor Diego Dibitetto, Martin Liptay, Francesca Vivalda, Hülya Doğan, Ewa Gogola, Martín González Fernández, Alexandra A. Duarte, Jonas Schmid, Morgane Decollogny, Paola Francica, Sara Przetocka, Stephen T. Durant, Josep V. Forment, Ismar Klebic, Myriam Siffert, Roebi de Bruijn, Arne Nedergaard Kousholt, Nicole A. Marti, Martina Dettwiler, Claus Storgaard Sørensen, Jean‐Christophe Tille, Manuela Undurraga, Sana Intidhar Labidi‐Galy, Massimo Lopes, Alessandro A. Sartori, Jos Jonkers, Sven Rottenberg

    Vydáno 2024
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  20. 20
    Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

    Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer Autor Mohammad Asim, Firas Tarish, Heather Zecchini, Kumar Sanjiv, Eleni Gelali, Charles Massie, Ajoeb Baridi, Anne Y. Warren, Wanfeng Zhao, Christoph Ogris, Leigh‐Anne McDuffus, Patrice Mascalchi, Greg Shaw, Harveer Dev, Karan Wadhwa, Paul W.G. Wijnhoven, Josep V. Forment, Scott K. Lyons, Andy G. Lynch, Cormac O’Neill, Vincent Zecchini, Paul S. Rennie, Aria Baniahmad, Simon Tavaré, Ian G. Mills, Yaron Galanty, Nicola Crosetto, Niklas Schultz, David E. Neal, Thomas Helleday

    Vydáno 2017
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