Search Results - José M.P. Freije

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  1. 1
    The hallmarks of aging as a conceptual framework for health and longevity research

    The hallmarks of aging as a conceptual framework for health and longevity research by Antonio G. Tartiere, José M.P. Freije, Carlos López-Otı́n

    Published 2024
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  2. 2
    Metabolic Control of Longevity

    Metabolic Control of Longevity by Carlos López‐Otín, Lorenzo Galluzzi, José M.P. Freije, Frank Madeo, Guido Kroemer

    Published 2016
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  3. 3
    Apolipoprotein D is the major protein component in cyst fluid from women with human breast gross cystic disease

    Apolipoprotein D is the major protein component in cyst fluid from women with human breast gross cystic disease by Milagros Balbı́n, José M.P. Freije, Antonio Fueyo, Luis Sánchez‐Pulido, Carlos López-Otı́n

    Published 1990
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  4. 4
    Differential Effects of Transforming Growth Factor-β on the Expression of Collagenase-1 and Collagenase-3 in Human Fibroblasts

    Differential Effects of Transforming Growth Factor-β on the Expression of Collagenase-1 and Collagenase-3 in Human Fibroblasts by José A. Urı́a, María Jiménez, Milagros Balbı́n, José M.P. Freije, Carlos López-Otı́n

    Published 1998
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  5. 5
    Deubiquitinases in cancer: new functions and therapeutic options

    Deubiquitinases in cancer: new functions and therapeutic options by Julia M. Fraile, Vı́ctor Quesada, David Rodrı́guez, José M.P. Freije, Carlos López‐Otín

    Published 2011
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  6. 6
    ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism

    ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism by Santiago Cal, José M.P. Freije, José M. López, Yoshikazu Takada, Carlos López-Otı́n

    Published 2000
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  7. 7
    The deubiquitinase <i>USP54</i> is overexpressed in colorectal cancer stem cells and promotes intestinal tumorigenesis

    The deubiquitinase <i>USP54</i> is overexpressed in colorectal cancer stem cells and promotes intestinal tumorigenesis by Julia M. Fraile, Diana Campos-Iglesias, Francisco Rodríguez, Yaiza Español, José M.P. Freije

    Published 2016
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  8. 8
    Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor.

    Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor. by José M.P. Freije, Magnus Abrahamson, Ísleifur Ólafsson, Gloria Velasco, Anders Grubb, Carlos López-Otı́n

    Published 1991
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  9. 9
    Site-directed Mutation of Nm23-H1

    Site-directed Mutation of Nm23-H1 by José M.P. Freije, Pilar Blay, Nicholas J. MacDonald, Richard E. Manrow, Patricia S. Steeg

    Published 1997
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  10. 10
    Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions

    Human progeroid syndromes, aging and cancer: new genetic and epigenetic insights into old questions by César Luis Janeiro Ramírez, Juan Cadiñanos, Ignacio Varela, José M.P. Freije, Carlos López-Otı́n

    Published 2006
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  11. 11
    Site-directed Mutagenesis of nm23-H1

    Site-directed Mutagenesis of nm23-H1 by Nicholas J. MacDonald, José M.P. Freije, Mary L. Stracke, Richard E. Manrow, Patricia S. Steeg

    Published 1996
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  12. 12
    Loss of GLUT4 Induces Metabolic Reprogramming and Impairs Viability of Breast Cancer Cells

    Loss of GLUT4 Induces Metabolic Reprogramming and Impairs Viability of Breast Cancer Cells by Pablo Garrido, Fernando G. Osorio, Javier Morán, Estefanía Cabello, Ana Alonso, José M.P. Freije, C. González

    Published 2014
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  13. 13
    Human cystatin D. cDNA cloning, characterization of the Escherichia coli expressed inhibitor, and identification of the native protein in saliva

    Human cystatin D. cDNA cloning, characterization of the Escherichia coli expressed inhibitor, and identification of the native protein in saliva by José M.P. Freije, Milagros Balbı́n, Magnus Abrahamson, Gloria Velasco, Henrik Dalbøge, Anders Grubb, Carlos López-Otı́n

    Published 1993
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  14. 14
    A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential.

    A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential. by Nicholas J. MacDonald, Abel De La Rosa, Mary Benedict, José M.P. Freije, H Krutsch, Patricia S. Steeg

    Published 1993
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  15. 15
    Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas

    Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas by José M.P. Freije, Irene Díez-Itza, Milagros Balbı́n, Luis Sánchez‐Pulido, Rafael Blasco, Jorge Tolivia, Carlos López‐Otín

    Published 1994
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  16. 16
    Membrane Type 4 Matrix Metalloproteinase (MMP17) Has Tumor Necrosis Factor-α Convertase Activity but Does Not Activate Pro-MMP2

    Membrane Type 4 Matrix Metalloproteinase (MMP17) Has Tumor Necrosis Factor-α Convertase Activity but Does Not Activate Pro-MMP2 by William English, Xosé S. Puente, José M.P. Freije, Vera Knäuper, Augustin Amour, Ann Merryweather, Carlos López-Otı́n, Gillian Murphy

    Published 2000
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  17. 17
    Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function

    Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function by Guillermo Mariño, Alejandro P. Ugalde, Álvaro F. Fernández, Fernando G. Osorio, Antonio Fueyo, José M.P. Freije, Carlos López-Otı́n

    Published 2010
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  18. 18
    Nuclear envelope alterations generate an aging‐like epigenetic pattern in mice deficient in Zmpste24 metalloprotease

    Nuclear envelope alterations generate an aging‐like epigenetic pattern in mice deficient in Zmpste24 metalloprotease by Fernando G. Osorio, Ignacio Varela, Ester Lara, Xosé S. Puente, Jesús Espada, Raffaella Santoro, José M.P. Freije, Mario F. Fraga, Carlos López-Otı́n

    Published 2010
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  19. 19
    Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias (Northern Spain)

    Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias (Northern Spain) by Pilar Blay, Iñigo Santamarı́a, Ana S. Pitiot, M. Luque, Marta G. Alvarado, Ana Lastra, Yolanda Fernández, Ángeles Paredes, José M.P. Freije, Milagros Balbı́n

    Published 2013
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  20. 20
    Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53

    Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53 by Alejandro P. Ugalde, Andrew Ramsay, Jorge de la Rosa, Ignacio Varela, Guillermo Mariño, Juan Cadiñanos, Jun Lü, José M.P. Freije, Carlos López‐Otín

    Published 2011
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