檢索結果 - Joris Pothof

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  1. 1
    Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options

    Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options 由 Wilbert P. Vermeij, Jan H.J. Hoeijmakers, Joris Pothof

    出版 2015
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  2. 2
    The central role of DNA damage in the ageing process

    The central role of DNA damage in the ageing process 由 Björn Schumacher, Joris Pothof, Jan Vijg, Jan H.J. Hoeijmakers

    出版 2021
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  3. 3
    MicroRNAs, the DNA damage response and cancer

    MicroRNAs, the DNA damage response and cancer 由 Maikel D. Wouters, Dik C. van Gent, Jan H.J. Hoeijmakers, Joris Pothof

    出版 2011
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  4. 4
    Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation

    Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation 由 Jeroen Bakkers, Carina Kramer, Joris Pothof, Nicolette E. M. Quaedvlieg, Herman P. Spaink, Matthias Hammerschmidt

    出版 2004
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  5. 5
    Identification of genes that protect the<i>C. elegans</i>genome against mutations by genome-wide RNAi

    Identification of genes that protect the<i>C. elegans</i>genome against mutations by genome-wide RNAi 由 Joris Pothof, Gijs van Haaften, Karen L. Thijssen, Ravi S. Kamath, Andrew Fraser, Julie Ahringer, Ronald H.A. Plasterk, Marcel Tijsterman

    出版 2003
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  6. 6
    Identification of Conserved Pathways of DNA-Damage Response and Radiation Protection by Genome-Wide RNAi

    Identification of Conserved Pathways of DNA-Damage Response and Radiation Protection by Genome-Wide RNAi 由 Gijs van Haaften, Ron Romeijn, Joris Pothof, Wouter Koole, Leon H.F. Mullenders, Albert Pastink, Ronald H.A. Plasterk, Marcel Tijsterman

    出版 2006
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  7. 7
    Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing

    Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing 由 Saurabh Gombar, Hwa Jin Jung, Dong Feng, Brent Calder, Gil Atzmon, Nir Barzilai, Xiao‐Li Tian, Joris Pothof, Jan H.J. Hoeijmakers, Judith Campisi, Jan Vijg, Yousin Suh

    出版 2012
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  8. 8
    Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis

    Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis 由 Kyra N. Smit, Jiang Chang, Kasper Derks, Jolanda Vaarwater, Tom Brands, Robert M. Verdijk, Erik A.C. Wiemer, Hanneke W. Mensink, Joris Pothof, Annelies de Klein, Emine Kılıç

    出版 2019
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  9. 9
    Organoids Derived from Neoadjuvant FOLFIRINOX Patients Recapitulate Therapy Resistance in Pancreatic Ductal Adenocarcinoma

    Organoids Derived from Neoadjuvant FOLFIRINOX Patients Recapitulate Therapy Resistance in Pancreatic Ductal Adenocarcinoma 由 Elham Aïda Farshadi, Jiang Chang, Bharath Sampadi, Michail Doukas, Freek Van ‘t Land, Fleur van der Sijde, Eveline E. Vietsch, Joris Pothof, Bas Groot Koerkamp, Casper H.J. van Eijck

    出版 2021
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  10. 10
    Genome-wide RNA polymerase stalling shapes the transcriptome during aging

    Genome-wide RNA polymerase stalling shapes the transcriptome during aging 由 Àkos Gyenis, Jiang Chang, Joris J. P. G. Demmers, Serena T. Bruens, Sander Barnhoorn, Renata M. C. Brandt, Marjolein P. Baar, Marko Rašeta, Kasper Derks, Jan H.J. Hoeijmakers, Joris Pothof

    出版 2023
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  11. 11
    Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II

    Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II 由 Barbara Steurer, Roel C. Janssens, Bart Geverts, Marit E. Geijer, Franziska Wienholz, Arjan F. Theil, Jiang Chang, Shannon Dealy, Joris Pothof, Wiggert A. van Cappellen, Adriaan B. Houtsmuller, Jurgen A. Marteijn

    出版 2018
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  12. 12
    Developmental and Activity-Dependent miRNA Expression Profiling in Primary Hippocampal Neuron Cultures

    Developmental and Activity-Dependent miRNA Expression Profiling in Primary Hippocampal Neuron Cultures 由 Myrrhe van Spronsen, Eljo Y. van Battum, Marijn Kuijpers, Vamshidhar R. Vangoor, M. Liset Rietman, Joris Pothof, Laura F. Gumy, Wilfred F. J. van IJcken, Anna Akhmanova, R. Jeroen Pasterkamp, Casper C. Hoogenraad

    出版 2013
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  13. 13
    Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer

    Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer 由 Myrthe Jager, Francis Blokzijl, Ewart Kuijk, Johanna Bertl, Maria Vougioukalaki, Roel Janssen, Nicolle Besselink, Sander Boymans, Joep de Ligt, Jakob Skou Pedersen, Jan H.J. Hoeijmakers, Joris Pothof, Ruben van Boxtel, Edwin Cuppen

    出版 2019
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  14. 14
    MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

    MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response 由 Joris Pothof, Nicole S. Verkaik, Wilfred F. J. van IJcken, Erik A.C. Wiemer, Van Thanh Ta, Gijsbertus T. J. van der Horst, Nicolaas G.J. Jaspers, Dik C. van Gent, Jan H.J. Hoeijmakers, Stephan P. Persengiev

    出版 2009
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  15. 15
    miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway

    miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway 由 Marijn T. M. van Jaarsveld, Patricia F. van Kuijk, Antonius W.M. Boersma, Jozien Helleman, Wilfred F. J. van IJcken, Ron H.J. Mathijssen, Joris Pothof, Els M.J.J. Berns, Jaap Verweij, Erik A.C. Wiemer

    出版 2015
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  16. 16
    miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells

    miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells 由 Marijn T. M. van Jaarsveld, Jozien Helleman, Antonius W.M. Boersma, Patricia F. van Kuijk, Wilfred F. J. van IJcken, Evelyn Despierre, Ignace Vergote, Ron H.J. Mathijssen, E. Berns, Jaap Verweij, Joris Pothof, Erik A.C. Wiemer

    出版 2012
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  17. 17
    DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity

    DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity 由 Marijn T. M. van Jaarsveld, Maikel D. Wouters, Antonius W.M. Boersma, Marcel Smid, Wilfred F. J. van IJcken, Ron H.J. Mathijssen, Jan H.J. Hoeijmakers, John W.M. Martens, Steven Van Laere, Erik A.C. Wiemer, Joris Pothof

    出版 2013
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  18. 18
    Different responses to DNA damage determine ageing differences between organs

    Different responses to DNA damage determine ageing differences between organs 由 Maria Vougioukalaki, Joris J. P. G. Demmers, Wilbert P. Vermeij, Marjolein P. Baar, Serena T. Bruens, Aristea Magaraki, Ewart Kuijk, Myrthe Jager, Sarra Merzouk, Renata M. C. Brandt, Janneke Kouwenberg, Ruben van Boxtel, Edwin Cuppen, Joris Pothof, Jan H.J. Hoeijmakers

    出版 2022
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  19. 19
    Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

    Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 由 Marjolein P. Baar, Renata M. C. Brandt, Diana A. Putavet, Julian D.D. Klein, Kasper Derks, Benjamin Bourgeois, Sarah Stryeck, Yvonne Rijksen, Hester van Willigenburg, Danny Feijtel, Ingrid van der Pluijm, Jeroen Essers, Wiggert A. van Cappellen, Wilfred F. J. van IJcken, Adriaan B. Houtsmuller, Joris Pothof, Ron W.F. de Bruin, Tobias Madl, Jan H.J. Hoeijmakers, Judith Campisi, Peter L.J. de Keizer

    出版 2017
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  20. 20
    Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice

    Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice 由 Wilbert P. Vermeij, Martijn E.T. Dollé, Erwin Reiling, Dick Jaarsma, César Payán‐Gómez, Cíntia R. Bombardieri, Haiyan Wu, Anton J.M. Roks, Sander M. Botter, Bram C. J. van der Eerden, Sameh A. Youssef, Raoul Kuiper, Bhawani Nagarajah, Conny T. van Oostrom, Renata M. C. Brandt, Sander Barnhoorn, Sandra Imholz, Jeroen L.A. Pennings, Alain de Bruin, Àkos Gyenis, Joris Pothof, Jan Vijg, Harry van Steeg, Jan H.J. Hoeijmakers

    出版 2016
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