Ngā hua rapu - Jonchere, Barbara

STAT3 as a new autophagy regulator mā Jonchère, Barbara, Bélanger, Audrey, Guette, Catherine, Barré, Benjamin, Coqueret, Olivier

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PDTM-02. TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA mā Jonchere, Barbara, Stripay, Jennifer, Pribnow, Allison, Zindy, Frederique, Min, Jaeki, Freeman, Burgess, Shelat, Anang, Rankovic, Zoran, Roussel, Martine

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Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis mā Vétillard, Alexandra, Jonchère, Barbara, Moreau, Marie, Toutain, Bertrand, Henry, Cécile, Fontanel, Simon, Bernard, Anne-Charlotte, Campone, Mario, Guette, Catherine, Coqueret, Olivier

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Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy mā Le Duff, Mélanie, Gouju, Julien, Jonchère, Barbara, Guillon, Jordan, Toutain, Bertrand, Boissard, Alice, Henry, Cécile, Guette, Catherine, Lelièvre, Eric, Coqueret, Olivier

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INSP-09. Using genetically engineered mouse models and patient-derived orthotopic xenografts to develop new therapies for pediatric brain tumors. mā Jonchere, Barbara, Pribnow, Allison, Morfouace, Marie, Shelat, Anang, Yu, Jiyang, Rankovic, Zoran, Gajjar, Amar, Northcott, Paul A, Robinson, Giles W, Roussel, Martine F

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Distinct Merkel Cell Polyomavirus Molecular Features in Tumour and Non Tumour Specimens from Patients with Merkel Cell Carcinoma mā Laude, Hélène C., Jonchère, Barbara, Maubec, Eve, Carlotti, Agnès, Marinho, Eduardo, Couturaud, Benoit, Peter, Martine, Sastre-Garau, Xavier, Avril, Marie-Françoise, Dupin, Nicolas, Rozenberg, Flore

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Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1 mā Jonchère, Barbara, Vétillard, Alexandra, Toutain, Bertrand, Lam, David, Bernard, Anne Charlotte, Henry, Cécile, Trécesson, Sophie De Carné, Gamelin, Erick, Juin, Philippe, Guette, Catherine, Coqueret, Olivier

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MEDB-42. GermlineElp1 deficiency promotes genomic instability and survival of granule neuron progenitors primed for SHH medulloblastoma pathogenesis mā Garcia-Lopez *, Jesus, Ahmad *, Shiekh Tanveer, Li *, Yiran, Gudenas, Brian, Kojic, Marija, Manz, Friedrik, Jonchere, Barbara, Mayasundari, Anand, Pitre, Aaron, Hadley, Jennifer, Paul, Leena, Batts, Melissa, Bianski, Brandon, Tinkle, Christopher, Orr, Brent, Rankovic, Zoran, Robinson, Giles, Roussel, Martine, Wainwright, Brandon, Kutscher, Lena, Lin #, Hong, Northcott #, Paul

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Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators mā Nishiguchi, Gisele, Keramatnia, Fatemeh, Min, Jaeki, Chang, Yunchao, Jonchere, Barbara, Das, Sourav, Actis, Marisa, Price, Jeanine, Chepyala, Divyabharathi, Young, Brandon, McGowan, Kevin, Slavish, P. Jake, Mayasundari, Anand, Jarusiewicz, Jamie A., Yang, Lei, Li, Yong, Fu, Xiang, Garrett, Shalandus H., Papizan, James B., Kodali, Kiran, Peng, Junmin, Pruett Miller, Shondra M., Roussel, Martine F., Mullighan, Charles, Fischer, Marcus, Rankovic, Zoran

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Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs mā Min, Jaeki, Mayasundari, Anand, Keramatnia, Fatemeh, Jonchere, Barbara, Yang, Seung Wook, Jarusiewicz, Jamie, Actis, Marisa, Das, Sourav, Young, Brandon, Slavish, Jake, Yang, Lei, Li, Yong, Fu, Xiang, Garrett, Shalandus H., Yun, Mi-Kyung, Li, Zhenmei, Nithianantham, Stanley, Chai, Sergio, Chen, Taosheng, Shelat, Anang, Lee, Richard E., Nishiguchi, Gisele, White, Stephen W., Roussel, Martine F., Potts, Patrick Ryan, Fischer, Marcus, Rankovic, Zoran

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Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer mā Slavish, P. Jake, Chi, Liying, Yun, Mi-Kyung, Tsurkan, Lyudmila, Martinez, Nancy E., Jonchere, Barbara, Chai, Sergio C., Connelly, Michele, Waddell, M. Brett, Das, Sourav, Neale, Geoffrey, Li, Zhenmei, Shadrick, William R., Olsen, Rachelle R., Freeman, Kevin W., Low, Jonathan A., Price, Jeanine E., Young, Brandon M., Bharatham, Nagakumar, Boyd, Vincent A., Yang, Jun, Lee, Richard E., Morfouace, Marie, Roussel, Martine F., Chen, Taosheng, Savic, Daniel, Guy, R. Kiplin, White, Stephen W., Shelat, Anang A., Potter, Philip M.

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Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma mā He, Chen, Xu, Ke, Zhu, Xiaoyan, Dunphy, Paige S., Gudenas, Brian, Lin, Wenwei, Twarog, Nathaniel, Hover, Laura D., Kwon, Chang-Hyuk, Kasper, Lawryn H., Zhang, Junyuan, Li, Xiaoyu, Dalton, James, Jonchere, Barbara, Mercer, Kimberly S., Currier, Duane G., Caufield, William, Wang, Yingzhe, Xie, Jia, Broniscer, Alberto, Wetmore, Cynthia, Upadhyaya, Santhosh A., Qaddoumi, Ibrahim, Klimo, Paul, Boop, Frederick, Gajjar, Amar, Zhang, Jinghui, Orr, Brent A., Robinson, Giles W., Monje, Michelle, Freeman III, Burgess B., Roussel, Martine F., Northcott, Paul A., Chen, Taosheng, Rankovic, Zoran, Wu, Gang, Chiang, Jason, Tinkle, Christopher L., Shelat, Anang A., Baker, Suzanne J.

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